CLINICALLY SIGNIFICANT ANTIBODIES IN TRANSFUSION

Antigen Antibody Speci city Clinically

System signi cant?

ABO Anti-A1 Rarely

Rh Anti-D, C, c, E, e Yes
Rh Anti-Cw Rarely
Kell Anti-K; Anti-k Yes
Kell Anti-Kpa Rarely
Kidd Anti-Jka, Jkb Yes
MNS Anti-M (reactive at 37°C) Occasionally
MNS Anti-M (not reactive at 37°C) Rarely
MNS Anti-N Rarely
MNS Anti-S, s, U Yes
Duffy Anti-Fya, Fyb Yes
P1 Anti-P1 Rarely
Lewis Anti-Lea, Leb ,Lea+b Rarely-No
Lu Anti-Lua Rarely
H Anti-HI (in A1 and A1B patients) No

Other Reactive by IAT at 37 °C Variable

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