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  • Immuno and Sero Midterm Lab

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    Suk Yeong Song
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    The document discusses different types of agglutination tests used to detect typhoid and paratyphoid infections. It describes direct and indirect agglutination tests using different antigens like O, H, and K antigens. The interpretation of increased antibody titers against different antigens can indicate acute, past, or mixed infections with Salmonella typhi or Salmonella paratyphi. A titer of 1:80 or greater is considered significant for detection of infection.

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    The document discusses different types of agglutination tests used to detect typhoid and paratyphoid infections. It describes direct and indirect agglutination tests using different antigens like O, H, and K antigens. The interpretation of increased antibody titers against different antigens can indicate acute, past, or mixed infections with Salmonella typhi or Salmonella paratyphi. A titer of 1:80 or greater is considered significant for detection of infection.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    6 views1 page

    Immuno and Sero Midterm Lab

    Uploaded by

    Suk Yeong Song
    The document discusses different types of agglutination tests used to detect typhoid and paratyphoid infections. It describes direct and indirect agglutination tests using different antigens like O, H, and K antigens. The interpretation of increased antibody titers against different antigens can indicate acute, past, or mixed infections with Salmonella typhi or Salmonella paratyphi. A titer of 1:80 or greater is considered significant for detection of infection.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    of 1

    types of Agglutination :

    • reverse
    passive
    Types of dilution
    •
    passive . compound
    • direct . simple
    serial
    agglutination inhibition
    •
    .

    •
    inhibition
    Co -

    aggulation
    INTERPRETATION:
    • INCREASE titer on OD Ag:

    streptozyme test
    indicates acute/ recent typhoid fever O antigen/
    makikita sa D tube

    ttemmaglvtination
    principle passive
    : INCREASE titer on OA, OB and OC:
    indicates acute/ recent paratyphoid infection O
    antigen/makikita sa A,B,C tube

    As ◦ tube method INCREASE titer on HD Ag:


    indicates previous/ past infection with typhoid

    /
    fever
    principle i Neutralization enzyme H antigen/makikita sa D tube
    Convalescent period na yung infection
    inhibition Vaccination against typhoid fever (May immunization na
    since may past history na ng infection)

    test INCREASE titer on HA, HB, HC:


    indicates past infection on S.paratyphi H antigen/
    Aso slide makikita sa A, B, C Tube

    principle
    :
    passive / indirect Agglv INCREASE titer on O and H Ag:
    infection Cross-reaction
    indicates mixed

    Significant titer: 1:80 (80)


    • Less than < 80 = normal
    • Greater than > 80 = indicative of infection

    lNeiLFeli# indirect
    direct
    -
    antibody
    -

    antigen
    -

    proteus 0×2 -

    p
    .

    vulgaris
    -

    0×19
    P mirabilis
    =
    -

    OXK
    Kingsbury strain
    post zone
    antigen excess

    -
    -

    "

    pro zone _
    antibody
    INI dat test
    Types of antigen i

    0 Ag somatic

    ]
    -

    H Ag -
    Flagellar antigen
    K Ag - Xi

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