Professional Documents
Culture Documents
com
51. The most common complication of a urethral stricture is:- urinary tract infection
52. Mild phimosis with minimal scarring, treatment:- preputioplasty
53. The Plastibel device can be used in infants for circumcision. The ring separates
between 5 and 8 days postoperatively
54. Frenulum Breve:- the frenulum is short, such that it causes pain when the foreskin is
retracted. Often confused with phimosis. Treatment is by frenuloplasty, which utilises
the Heineke Mikulicz principle to ‘lengthen’ the frenulum.
55. Most common cause of genital ulcer:- herpes
56. ‘Vanishing’ testis describes a condition in which a testis develops but disappears
before birth. The most likely cause for this is prenatal torsion. True agenesis of the
testis is very rare. Laparoscopy is useful in distinguishing these causes of clinically
absent testis from intra-abdominal maldescent.
57. Most common testicular appendage to undergo torsion is:- Appendix of the testis
(pedunculated hydatid of Morgagni)
58. The usual cause of varicocele is absence or incompetence of valves in proximal
testicular vein
59. Chylocele usually occurs due to- repeated filarial epididymo-orchitis. Primary
treatment is by aspiration. Long standing thick sacs have to be excised
60. The most common cause of a haematocele is vessel damage during needle drainage of
a hydrocele
61. Epididymal cysts:- single large cysts can be excised separately, recurrent or
multilocular cysts usually require partial or total epididymectomy. Excision should be
expected to interfere with the transportation of sperm from the testis on that side
62. Spermatocele is a unilocular retention cyst derived from some portion of the sperm-
conducting mechanism of the epididymis. A spermatocele typically lies in the
epididymal head above and behind the upper pole of the testis. Small spermatoceles
can be ignored. Larger ones need to be excised
63. Most common organism causing epididymo-orchitis:- in young men (Chlamydia
trachomatis) and in elderly (E.Coli). Treatment by Doxycycline or fluroquinolones
64. Main complication of mumps orchitis is:- testicular atrophy
65. Non-filarial elephantiasis can result from fibrosis of the lymphatics caused by
lymphogranuloma venereumor by persistent contact with irritant soils
UROLOGY PIN-POINTS: vivekurologist@yahoo.com
66. Carcinoma of scrotum in Chimney sweepers was the first reported occupational
cancer (described by Percival Pott in 1775).
67. Approximately 20 per cent of cases of infertility are caused entirely by the male
factor.
68. Semen analysis must be performed within 2 hours of the semen being produced
69. Sperm counts of less than 15 million sperm per mL are defined as oligozoospermia.
70. After Vasectomy, normal contraceptive precautions should continue until the success
of the operation is confirmed by semen analysis performed 12–16 weeks after
surgery. Spontaneous recanalisation, which may restore fertility unexpectedly and
chronic testicular pain may occur in up to 5 per cent of men.
71. First successful kidney transplant:- 1954, Joe Murray
72. University of Wisconsin solution discovered:- by Belzer and colleagues
73. Role of HLA antigens was first demonstrated by:- Dausset in 1958. Loci for HLA
antigens are located on short arm of chromosome 6
74. The single most important risk factor for chronic rejection after kidney transplantation
is acute rejection (with vascular inflammation) and recurrent episodes of acute
rejection
75. GVHD (graft versus host disease) most commonly involves:- skin
76. Mechanism of action:-
Calcineurin inhibitors (cyclosporine/tacrolimus) – blocks IL-2 gene transcription
mTOR inhibitors (sirolimus/everolimus) – blocks IL-2 receptor signal transduction
77. Acute rejection occurs in up to around 30 per cent of transplant recipients but usually
responds to a short course of high dose steroid therapy.
78. If the response to steroids is inadequate or if acute rejection recurs, acute rejection can
often be treated successfully by recourse to antilymphocyte globulin (ALG) therapy
79. Most common viral infection after transplant:- CMV. Treated with oral valganciclovir
or i.v. ganciclovir
80. BK virus is emerging as an important cause of graft dysfunction after renal
transplantation. The only effective treatment is to reduce the level of
immunosuppression to allow natural immune mechanism to regain control of the
virus.
81. Most common fungal infection after transplant:- pneumocystis jiroveci. Treatment by
chemoprophylaxis with cotrimoxazole
UROLOGY PIN-POINTS: vivekurologist@yahoo.com
82. Most common malignancy after transplant- skin cancer (MC squamous cell Ca)
83. Transplant patients have a 300-fold increased risk of developing Kaposi’s sarcoma
84. DCD (deceased after cardiac death) donors can be grouped according to the
Maastricht classification as follows:
• category 1: dead on arrival at hospital;
• category 2: resuscitation attempted without success;
• category 3: ‘awaiting cardiac arrest’ after withdrawal of support;
• category 4: cardiac arrest while brain dead;
• category 5: cardiac arrest and unsuccessful resuscitation in hospital.
Maastricht categories 1, 2 and 5 donors are sometimes referred to as
uncontrolledDCD donors
85. Creutzfeldt–Jakob disease, sepsis, HIV, HBV, malignancy in last 5 yrs (except
primary CNS tumours, non-melanotic skin tumours and carcinoma in situ of cervix)
are contraindications for organ donation
86. In DCD donors there is an inevitable period of warm ischaemia (up to 45 minutes is
acceptable) between the diagnosis of death (cardiorespiratory arrest) and cold
perfusion of the organs
87. Cold storage time for kidney:- optimum (<18hrs), maximum (upto 36 hrs)
88. Many of the glomerulonephritides (especially IgA, focal segmental
glomerulosclerosis, and mesangiocapillary glomerulonephritis types I and II) may
recur in a kidney transplant, and sometimes can lead to early graft failure (especially
focal segmental glomerulosclerosis).
89. In the case of primary oxalosis, combined kidney and hepatic transplantation is
usually undertaken to eliminate the metabolic defect and thereby prevent early graft
failure from the formation of further oxalate stones.
90. Acute tubular necrosis usually resolves within first 4 weeks of transplant
91. CBAVD (Cong. Bilateral Absence of Vas Deferens) is associated with mutation of –
CFTR gene
92. Normal serum testosterone = 400-700 ng/dl
93. PDE5 inhibitors like sildenafil (used for erectile dysfunction) are contra-indicated
with- Nitrates