Cambridge International School – Kurdistan

Biology quiz
AS Level - 2

Student Name: ……………………………………………………………

Date: …………………………………………………………………………
Class: ………………………………………………………………………….
1 Which of these events are part of mitosis?
1 interphase
2 telophase
3 cytokinesis
A 1, 2 and 3 B 1 and 3 only C 1 only D 2 only

2 During which phase of the cell cycle does DNA replication take place?
A G1 B G2 CM DS

3 Which row is correct for guanine?

4 Meselsohn and Stahl investigated DNA in bacteria. They grew bacteria in a medium with only heavy
nitrogen, 15N, until all of the bacterial DNA was heavy.
These bacteria were moved from a heavy nitrogen medium and cultured in a medium with only light nitrogen,
14N.
A sample of bacteria was collected from the first generation in the medium containing light nitrogen and their
DNA was analysed.
Hybrid DNA contains both heavy and light DNA.
Which row shows the percentage of heavy DNA strands and the percentage of hybrid DNA molecules in the
first generation produced in the medium containing light nitrogen?
5 Which is the correct DNA triplet on the original DNA template that codes for the amino acid histidine (His)?

A CAU B CGT C GTA D GUA

6 One of the chromosomes in a nucleus has a telomere which contains many repeats of the base sequence
TTAGGG.
This chromosome was extracted from four different cells and the total number of bases in the telomere was
determined. Which total number of bases was found in the cell that had undergone the most mitotic
divisions?
A 5548 B 5580 C 5645 D 5700
7 The chromosome content of each daughter cell must be identical to that of the mother cell for successful
cell replacement when repairing tissues.
Which stages of mitosis make sure that each daughter cell receives one chromatid from each chromatid pair?
A prophase and metaphase
B metaphase and anaphase
C anaphase and telophase
D telophase and interphase

8 Which of these statements about cytokinesis is always true?

1 Cell structures replicate.
2 Cell structures are shared between two cells.
3 Nuclear envelope reforms.
A 1, 2 and 3 B 1 and 3 only C 2 only D 3 only

9 Which statement is correct about the number of telomeres present in prophase of a human body cell?
A 46 as there is one telomere at the end of 46 chromosomes
B 92 as there is one telomere at each end of 46 chromosomes
C 92 as there is one telomere at the end of 92 chromatids
D 184 as there is one telomere at each end of 92 chromatids
10 Which statement explains why DNA replication is described as semi-conservative?
A Half of each original strand is conserved in each new molecule of DNA.
B Half of the base sequence of each strand is conserved in each new molecule of DNA.
C Only one strand of DNA is used as a template during replication.
D The template for each new molecule of DNA is one strand of the original molecule.

11 A section of a DNA molecule has the coding sequence: AGGCAATGGC. Which statements are correct?
1 This coding sequence contains 3 pyrimidines.
2 The double-stranded DNA of this section contains 26 hydrogen bonds between complementary bases.
3 The double-stranded DNA of this section has 20 sugar-phosphate bonds.
A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

12 In 1953, James Watson and Francis Crick published details about the structure of DNA.
They used experimental results from other scientists to help them work out the structure and then built a
model of a section of a DNA molecule, using pieces of wire and metal, with clamp stands to hold the model in
place. This is shown in Fig. 2.1.

Fig. 2.1
 (a) Watson and Crick used results from work carried out by Erwin Chargaff. He found that the proportions
of the bases A, T, C and G were different in different species, but within each species: • the proportion
of A was equal to the proportion of T • the proportion of G was equal to the proportion of C.
(i) Name the bases A, T, G and C.
A ........................................................................................................................................................................
T .......................................................................................................................................................................
G ........................................................................................................................................................................
C ................................................................................................................................................................... [2]
(ii) Suggest and explain how Chargaff’s findings helped Watson and Crick work out the structure of DNA
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(b) Phoebus Levene isolated the nucleotides of DNA and identified the carbohydrate component of each
nucleotide. State the name of this carbohydrate component.

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(c) Before the discovery of the structure of DNA as the molecule of inheritance, scientists thought that
proteins were most likely to be the molecules that carried information.
Suggest how the structure of proteins made scientists think that these were the molecules that carried
information.
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[Total: 9]