Professional Documents
Culture Documents
Advantages Applications
Challenges
Water
Li-water Tech.
pollution
intensive cost (407.4)
Fe
Mining Fe
Manufacturing
China (314th)
Heral Se
Usage
Range
Transportation
storage
Fire
Triangle
Fire
Fuel
↳
Oxygen
Page 2 of 12
causes
eg. NOKIA
I
Production flaws, Impurities
↑
Gue
-
Design Fun
+- Many
acturin
g Thermal
Thermal -> Heat ->
Paro-
Disposal 2 -
Solutions
GST/DBT/IR
lectric Vehicles
=
Advantages
Healthy environment (cleand
efficient energy/ Benefits
No pollutants No tailpipe
Maintence
emissions
Decarbonize energy ·
1SOX, NOx
(CO2, HG)
eg. WHO INDC security ·
running cost
eg. electric ·
Noise
2801. oil
engines aimports)
(v TT1.)
cg.
Page 3 of 12
Challenges
0
Govt.
Manufacturing
-
-
A -
-
↓ supply sides
↓
sick)
I
↳Demand
↓ A
I cost -
Policy
·
R
Technolog charging
.
&
C
. 8·
anga
·
&
8
- ⑧
⑤
&
cost
·
Five
·
Semi-conductors,
e.
controllers
↑
Solution
Policy 2020
-
A:Autonomous. As
· content
Uscus create
I
Dale, owned
by Tech.
I
·
Trust less
- Decentralize
~
Democratize
R2
S WPI
WDL 43
#
s
WP3
B
WPY
1
A
56
Page 4 of 12
****- Digital Decentralized Ledger
Blockchain
eb -
Decentralized
I- Immutable
Advantages
->
-> I
-
Encrypted
->
I-
Traceable, Transparent
Health
gov Smart
EE X
social
Governance con tracts
Fur
Economy cryptocurrency
mainder
try
eg. subl
Inclus
San
Banking
management
-
Agriculture
eg. Land
records
Challenges solutions
Privacy
Institutions COE
Infra
power, Memory, Initiatives
Indiachain
Technology Finance
others..... HRM
↑
Page 5 of 12
M Malaficl ->
Scars/Frands
I
A Anonymous E and -
Cryptocurrency B Blockchain. ssues Energy
C.
border flow
C
cross
R
Regulations gal
I
Jurisdiction
Features B Decentralized P
I
I
E
Encrylated
F Fast
stangiblePrietalan
NFT
Applications Working
Blockchain
-
Digital
art
Music Industry
NFT
Gaming ·
Digital
wallet
Market place
Challenges Int
Ownership Economic orgy. Env
security
crime
↑
↑
V I f I
W
Energy
2 2
status Terror
No
legal Finance,
IP
Tracing,
Speculative frouds
cost
Monay
tracking laundering
Page 6 of 12
Medicine
DRONE
·
from
~
spray,
*
Health
Agriculture seeding
&
National
Gun
Security
Applications Law & Order
·
crowd, traffic
Disaster
Management Urban-Rural
Environment Development
Surveillance,
·
Search,
Monitoring SVAMITUA
& ·
·
Rescue Check
poaching
*
A
-
free
Challenges
Accessibility. security
I
Anonymity -
Privacy
Drone corridors
Drone
-
classification
Air zone
Mini yellow
Page 7 of 12
Nuclear
Energy
3 e
I tag programme
/Nuclear Stage I stage 2
Natural ->PHWR
electricity X in
Energy
-
zit uranium Pu
Large hydro v] -> FBR
->
electricity
Basket Depleted
-> PV, U233
5391
--wind
coal
I
35.4.1. -
Solar
(T., US
R. E AHWR
Biomass
small
hydro Stage 3
electricity
Nuclear Fission
· Ex. NO CO2, Sox,NOx
-
Advantages e
:
↳ ·
Strategic oil
↑ z...$
Energy Security
Thorium
Radio isotolos -
Health
cycl I -
Defence reactors
per 1
unit
3
compact
decentralize
-
↳
submarine etc. ·
! generation.
Space ->
RTG
↑
- IT T
Land 1000 MW wind 360 times less
·
usage ->
Initial cost $
· Meltdown
control
regime Tech. i
Kaste Mgmt.- radio active
Iimports Fuel
. 3
/
u
Proliferation
> WMD
-
↑
decontamination
-
Water
- land acquisition
Nuclear Fusion
XS. Fission
Energy density
Raw Material easy -
availability
Waste - less radio-active
BIO-TECHNOLOGY branding,
T F:Biofertilizer
7 P:BioPesticicle - ItTacin, Microbial pesticides
↓Animal:Fertilization, Growth
hormone
-
Marine:Fish, seaweed farming
biofuels. bio-remediation Environment
·
~
de-extinction BD Others
·
<
chemicals, enzymes
Industry
·
<
bio
degradable plastics proan oftherapeutic drugs;
TR.DNA:Biomanufacturing
Mass
-
e.g. Insulin
·
Taste, texture,
nutrition, Food Stem cell Therapy: regenerative medicine
e.g.
fermentation
<Gene Therapy:Personalized medicine, genetic defects, CRISPR-CAS9
Health
>Molecular
clicy:understanding pathophysiology - PCR, ELISA;medical imaging
Privacy
-
Socio-economic, affordability
~
Ethical >
Designer baby, ecological harm
VACCINES At
GOVERNANCE
Drugs and cosmetics
trial
Act
1940.
:
Trial:
-
↳
oval:
·
DCG]
-
permission
·
ICMR -
registration Pd ( Ph2
0
Pb5
I
I Central
Clinical Drug Standard
Pharmacology Exploratory confirmatory
Control Org.
I I I
2 10-12 1000 -
2000
TYPES: ⑳
-
X - X X
Live
Inactivated subunit, Viral RNA
alternated vector
in
Conjugate
X Y
↓ - X
·
weakene ·
Killed virus ·
Specific piece, ·
target DNA ·
Antigen MRNA
virus
t
↑
Sequence
↓
S
harmless virus
vector
x
eg. Smallpox,
chickenpox,
cy. Polic x
↑ ↓
MMR Hepa titis A, Covishield 26.COVID (Mockuna,
eg. IS
·
3
Covaxcin
Pfizer)
sputnik,
1
Page 9 of 12
↑
Genome / Gene
Editing Tools
T
· Genetic
engineering gene+--
-
SgRNA
non-specific specific (guide RNA)
IBSC Insc. bio safety
3
-
SDN1
(CAS9I
Types
committee
&FN TAKEN CRISPR
SDN2
(molecular
scissor)
Keywords trait
stocking, germline
L mutation, precision medicine,
off-targetmutations,
drive
gene
Applications
↑
(Zika)
Diseases-modelling disease, CART-Kille
malignant cells, vector borne
Jiankui-R5
·
He
I
correct mutations (sparent baby)
-
Trait
stacking-selecting several traits
Functional
genes screening-Precision
-
medicine
Mutation
libraries-predicting diseases I cre
environment-De-extinction
Food
security-yield, disease resistance, taste, texture
Challenges n
↑
Off-targetmutations:
-
Germline
editing: permanentpopulation change
train
Ecological Impact:Gene
Unknown
drive:ve
throughout population
-> Sickejjects:Jesse Gelsimer (Death), Leukenria
q
unethical
Designer babies: He Jiankui
-
mRNAto
uses
antigen-encoding stimulate
adaptive immune response.
-
-- Advantages -
Naked viral
↑
Narro
MRNA Particle Vector
case
of design-Moderna mRNA-1273 (days)
injection vecher Faster
manufacturing -
22
days
Lower cost
of production
interaction with Genomic DNA:
No
cytoplasm
Higher efficacy. Pfizer-Bion Tech (90-95%)
Reactogenicity-autoimmune response
·
Manufacturing
·
Distribution
Hesilancy - new
technology Monopoly
·
Stem Cell
Therapy Classification
·
all specialized cells
Timeline
Potency
E A I Induced I
Embryonic Adult P
M
stem stem pluripotent Totipotent Pluripotent Multipotent
How it works? alls alls stem cells
stain
cells -> specialization -
Implantation
extraction
Advantages
-
↑
Regenerative medicine. Repair response of diseased, dysfunctional
or
injured tissues
Parkinsons, Diabetes
eg.
Organ repair/transplant:reduced I rejection risk
Revenue
T
- Food security
> SDG Goals
Advantages/Benefits Govt.
Income
>
Environment - Soil
society
Reduced tocicity
-
Nutrition prices
security
Foreign past
-super was
funded i
PSCC-
GEAL,
Monocropping
Regulation ->
Biodiversity ->
Govt BD TF
(2004)
Reduced
Income [
Farmet
Greenpeaut yield 2
Industry >Monopoly Price manip.
↑
->
-
Terminator seeds
↓
SOCIO
Govt. sector withdraw
economic
Manual <- HT
labour
To T Page 12 of 12
IPR Economic Growth
G Science
WTO
Rights FBI
Innovation.
Innovation (comp.
d
.
0 11 investment
Recover
A
-
*
·
RnD
·Products
2 ·
services/cost
·
Knowledge sharing
⑳
Governance
L
X - ↓
International Institutions
were e
Acts
e
Policy -
WTO-TRIPS
· The Patents Act, 1970
·
National
· IPR · Indian Patent office.
WIPO
·
policy, 1970
The
·
Geographical
Indication of Goods
Act, 1999
0
IPR Issues $ d
-
T
IPO
Evergreening
·
-
Institutional Pancency
-
IPAB
x
CL.
Lagal Adjudication
·
IPR Issues
-
· Data X
MNC 0 7. Awareness
Exclusivity I A x knowledge flow
·
Monopoly
International
1
special 301 Report
-
India-EU FTA