Histology PHL 101

Assessment 4 (Blood)

Question I. Read the following statements. If the statement is true, write (√).
If the statement is false, write (X).

1- The number of RBCs is about 200,000 – 400,000 / mL³

2- Eosinophils secrete histaminase enzyme.
3- Neutrophils are the first line of defense against micro-organisms.
4- Neutrophil has a central rounded nucleus.
5- Blood platelets have large segmented nuclei.
6- RBC’s are rounded discs with bi-convex surfaces.
7- Basophils have a function nearly similar to mast cells.
8- Monocytes are the largest leukocytes.
9- Eosinophils have a large kidney-shaped nucleus.
10- Lymphocytes are considered the first line of defense against the micro-organisms.
11- Basophils have S-shaped nucleus and coarse basophilic granules.
12- Blood film could be stained with Giemsa stain.

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Question II. Choose the correct answer that best completes the statement
or answers the question from the alternatives a, b, c or d.

1- Which of the following cells increase in number during acute inflammation?

a) Neutrophils.
b) Basophils.
c) Lymphocytes.
d) Eosinophils.
2- When B lymphocyte is activated, it differentiates into a ……....
a) pericyte.
b) plasma cell.
c) macrophage.
d) mast cell.
3- Which of the following cells are NOT seen in a blood film?
a) Monocytes.
b) Megakaryocytes.
c) Neutrophils.
d) Lymphocytes.
4- Megakaryocytes are present in the ……….
a) connective tissue.
b) blood plasma.
c) bone marrow.
d) Peritoneum.
5- What is the special stain for macrophages?
a) Iron hematoxylin.
b) Sudan black.
c) Toluidine blue.
d) Trypan blue.
6- The major signs and symptoms of allergic diseases are due to release of …..….
a) heparin.
b) antibodies.
c) histamine.
d) eosinophil chemotactic factor.

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7- In a case of acute tonsillitis, which type of the following cells will be increased?
a) Lymphocytes.
b) Plasma cells.
c) Basophils.
d) Neutrophils.

8- Thrombocytes are stained with ………… stain.

a) Silver.
b) Toluidine blue.
c) Leishmann.
d) Iron haematoxylin.

9- Which cell of the following doesn’t contain Azurophil granules?

a) neutrophil.
b) basophil.
c) monocyte.
d) mast cell.

10- Macrophages are derived from…….

a) lymphocytes.
b) monocytes.
c) bone marrow.
d) neutrophils.

11- Which of the following cells can form foreign body giant cell?
a) Eosinophils
b) Basophils
c) Monocytes
d) Lymphocytes

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Question III: The following figures represent blood and connective tissue
cells. Examine them carefully then answer the related questions

1- Discriminate the cells that play a role during acute infection (inflammation)?
Explain their role.
2- Clarify the functional relationship between the cells (B) & (E).
3- Compare between cells (A) & (D) regarding their structure.
4- Identify the cell that is considered as the second line of defence against
micro-organisms.