BIOLOGICAL MOLECULE ( PROTEIN )

( SET 1 )
1. (2009 ) Lysine and glutamic acid can be distinguished by 6. (1996) Which of the following are the important of globular protein for
A. the position of their amino groups. organism.
B. the position of their carboxyl group I As carrier molecule
C. the composition of their side chain II As buffer
D. their ability to form peptide bonds. III For the formation of hair and nails of organism
IV For the formation of enzymes
2. The characteristic and of an amino acid are determined by the A. I, II and III D. II, III and IV
A. peptide bond B. side group B. I, II and IV E. I, II, III and IV
C. amino group D. carboxyl group C. I, III and IV

3. (2006 ) Which of the following contributes to the secondary structure of a 7. (1996) Which of the following statements are true about the structure of
protein? protein?
A. Peptide bond B. Hydrogen bond I The total amount of free amino and carboxyl group decreases when
C. Van der waal force D. Hydrophobic interaction protein are hydrolysed.
II The destruction of tertiary structure of protein decreases its solubility
4. (2007) Which molecular group and characteristic correspond? III Myoglobin cannot form the quaternary structure
IV All fibrous protein are not elastic
Group Characteristic V Collagen molecules form insoluble fibrous protein
A Methyl Polar, involved in hydrophilic reaction
A. I, II, III and IV D. I, III, IV and V
B Carboxyl Basic, involved in the formation of B. I, II, III, IV and V E. II, III, IV and V
peptide bond. C. I, II, III and V
C Amino Acidic, involved in the formation of
peptide bond 8. (1997) The differentiates among protein molecules is determined by
D hydroxyl A. alkyl group of certain amino acids
Polar, involved in condensation and
B. R group of certain amino acids
hydrolytic reaction
C. the amino acid sequence of protein molecules
D. peptide bond(s) between amino acids
5. (1996) Which of the following combination is true about fibrous protein?
E. carboxyl group of certain amino acids.
Molecular Solubility in Buffer Examples
9. (1998) The basic structure of amino acid is as shown below
structure water effect
A Primary Yes Yes immunoglobulin
B Secondary Yes No Tendon
C Secondary No Yes Haemoglobin
D Tertiary No Yes Amylase
E Secondary No No Keratin
 This amino acid is
I hydrophilic III negatively charged
II acidic IV insoluble in water

A. I only C. I, II and III

B. I and II only D. II, III and IV
Among the side chains of the amino acid, which one produces buffer
property for protein? 12. (2008) Which of the following contributes to the secondary structure of a
A. R and H D. H and NH2 protein?
B. R and COOH E. NH2 and COOH A. Peptide bond C. Hydrogen bond
C. R and HN2 B. Van der waal force D. Hydrophobic interaction.

10. (1999) Which of the following statements concerning proteins and amino 13. (2009 ) Lysine and glutamic acid can be distinguished by
acids are true? A. the position of their amino groups.
I Most enzymes are globular protein B. the position of their carboxyl group
II The formation of the peptide linkage occurs through a condensation C. the composition of their side chain
process. D. their ability to form peptide bonds.
III All amino acids which are needed can be synthesised by the human
body 14. (2010) The characteristic and of an amino acid are determined by the
IV Non-protein components attached to protein belong to the prosthetic A. peptide bond C. Amino group
group. B. side group D. Carboxyl group
V The various amino acids found in protein have different R group.
15. ( 2011) Which proteins conformation corresponds to its correct description?
A. I, II and IV D. II, III and IV
B. I, II and V E. II, III and V Proteins’s Description
C. I, IV and V conformation
A Primary A repeated regular structure of a
11. (2004) The following is the formula for an amino acid. polypeptide chain.
B Secondary The coiling and folding of a
polypeptide chain involve
hydrogen bonds only
C Tertiary The aggregation of two or more
proteins subunits.
D Quartenary The complex three dimensional
structure of polypeptide chains.
 BIOLOGICAL MOLECULE ( PROTEIN )
( SET 2 ) 5. Four types of protein and their example are shown in table below

1. Which amino acid is non-polar? (Stpm 2012) Type of protein Example

A. Serine C. Glycine I Signal protein P Actin
B. Lysine D. Aspartate II Storage protein Q Casein
III Structural protein R Insulin
2. Which protein is non-globular? (Stpm 2013) IV Contracrile protein S Collagen
A. Lipase C. Collagen
B. Cellulase D. Myoglobin Which types of protein correspond correctly to their respective
examples? (stpm 2012)
3. Keratin in human hair has a high percentage of the amino acid cysteine which I II III IV
is responsible for the formation of straight or curly hair. Which is involved in A P R S Q
the formation of this trait? (stpm2014) B R Q S P
A. Ionic bond C R S P Q
B. Hydrogen bond D s q R P
C. Disulphide bridge
D. Hydrophobic interaction 6. Which of the following structures would contain the molecules P, Q, R
and S?
4. The structure of a protein is shown in the diagram below (stpm 2015)

Which product will be produced after the protein is organised?

A. Keratin C. Protease
B. Fibroin D. Collagen
 P Q R S A. It is hydrophilic
A Testosterone DNA Albumin Glycogen B. It is acidic
B Oestrogen DNA Collagen Cellulose C. It is negatively charged
C Testosterone DNA Lecithin Cellulose D. It is insoluble in water
D Oestrogen RNA Keratin Starch
12. Protein can act as buffers because
7. What would happen to a protein during electrophoresis when the pH of A. They are non polar
the buffer solution used is below its isoelectric point? [stpm 2016] B. They are amphoteric
A. The protein does not move C. They are large, colloidal molecules
B. The protein moves towards the anode D. The amino acids are linked by dipeptide bonds
C. The protein moves towards the anode to the cathode
13. Keratin in human hair has a high percentage of the amino acid cysteine,
8. Which is true about peptide bond? [stpm 2016/2015u] which is responsible for the formation of straight or curly hair. Which is
A. The formation of a peptide bond releases one water molecule. involved in the formation of this trait?
B. The tertiary structure of a protein is determined by its peptide bond A. Ionic bond
C. The characteristic of a protein molecule is determined by its peptide B. Hydrogen bond
bond C. Disulphide bridge
D. The peptide bond is formed between two acids with the same D. Hydrophobic interaction
characteristics
14. A peptide bond is formed between
9. Hydrophobic interaction occur at these levels of protein structure which A. An aldehyde group and an amino group
are B. An aldehyde group with an ester group
A. Primary and secondary C. An aldehyde group with a carboxyl group
B. Primary, secondary and tertiary D. A carboxyl group with an amino group
C. Tertiary and quaternary
D. Quartenary only 15. Which of the following is principally responsible for maintaining the α-
helix shape of secondary protein structure?
10. The secondary structure of protein A. Disulphide bond
A. The sequence of amino acid in the polypeptide chain B. Peptide bond
B. The coiling of the polypeptide chain C. Hydrogen bond
C. The folding of the coiled polypeptide chain D. Glycosidic bond
D. The linking together of two or more globular proteins

11. All of the following statements describe the amino acid below except
 BIOLOGICAL MOLECULE
( PROTEIN )
SET 3

1. Protein can function as pH buffers in cells because

A. Protein are soluble
B. Protein contain linked amino acids
C. Protein contain both amino and carboxyl group
D. Protein contain peptide bonds

2. Which of the following are examples of fibrous proteins?

I Keratin III Fibroin
II Collagen IV Silk

A. I and II C. I, II and III

B. II and III D. I, II, III and IV

3. Which function of protein does not correctly correspond to its

example? (stpm2020)

Function of protein Example

A Contractile Action
B Protection Immunoglobulin
C Structural Keratin
D Storage Lipoprotein