Professional Documents
Culture Documents
SENIOR
HIGH
SCHOOL
GENERAL BIOLOGY 1
1st Quarter-Module 1:
Life in a Cell
General Biology 1
Alternative Delivery Mode
Quarter 1 – Module 1: Life in a Cell
Republic Act 8293, section 176 states that: No copyright shall subsist in any
work of the Government of the Philippines. However, prior approval of the
government agency or office wherein the work is created shall be necessary for
exploitation of such work for profit. Such agency or office may, among other things,
impose as a condition the payment of royalties.
ii
Introduction
To assure that learning remains unhampered as the country battles against
In line with the aforementioned facts, this module is shaped primarily to aid
and assessments were generally compiled to solve the problem on lack of access to
CHAPTER
Learning Competency:
STEM_BIO11/12-la-c-1
Explain the postulates of the Cell theory.
Learning Objectives:
o Recognize the different scientists who contributed to the discovery
of the cell.
o Outline the history of the development of cell theory from its origin
to the present through completing a graphic organizer.
o Acknowledge scientists work and contribution through composing
a letter of appreciation.
PRETEST
Instruction: Write the letter that corresponds to the correct answer.
10. The date the first postulate of cell theory was published.
a. 1875 c. 1855
b. 1838 d. 1795
11. Which of the following describes the proper microscope care and technique.
a. Carry the microscope upright, with one hand on the arm and the
other under the base.
b. Always begin focusing with the greatest power lens available.
c. You can view the specimen without cover slips as it magnifies a
clearer view.
d. All of the above
12. ___________ are made up of at least one cell. Which word best fits in the
blank?
a. all living things c. animals
b. plants d. atoms
13. The increase in magnification causes _________.
a. decrease in the field of view c. decrease in number of specimen
b. decrease in working distance d. all of the above
14. What does the word cyto means?
a. dark c. cell
b. jelly d. small
15. Tiny structures that carry out cell functions are collectively called ________.
a. organelles c. animalcules
b. tissues d. ribosome
EXPLORE IT!
Instruction: Write mark if the picture below shows a living
thing and a mark if it displays a non-living thing. Please
indicate response in the box provided.
YEAST CORONA VIRUS
SEAWEED MUSHROOM
CORALS BACTERIA
Photo credits: yeast- exploreyeast.com, virus-webmed.com, seaweeds-alibaba.com, mushroom-kidsdiscover.com,
corals-scienmag.com, bacteria-sustainablity-times.com.
Now that you have
learned that cells can
only be present in a
living thing,
let us
navigate in detail how
first glimpse of cells
were revealed and
developed to a theory.
DISCOVERIES OF THE CELL THEORY
ROBERT HOOKE
o Used the compound microscope to observe
cork.
o Hooke observed that cork is composed
of small, hollow compartments.
o The parts prompted Hooke to think of
small rooms (cells) in a monastery, so
he gave them the same name: CELLS.
o Investigated cork through
experimenting with the compound
microscope and came up with the name
cells!
1665 o Hooke discovered the cell in 1665,
which started formulating the cell
theory!
ANTON VAN LEEUWENHOEK
o Study new approaches for creating
lenses to observe cloth.
o Leeuwenhoek’s microscope was more
powerful than Hooke’s compound
microscope.
o From investigating and experimenting
with his microscope, Leeuwenhoek
became one of the first scientists to refer
to living cells when he observed an
abundant number of single-celled
1670 organisms, which he called animalcules
(plant & animal), swimming in a drop of
Photo credits: Cartoon art- pinterest.com, Hooke- britannica.com, Leeuwenhoek-commons.wikipedia.org
MATTHIAS SCHLEIDEN
o Fascinated with plant cells, Schleiden used
the compound microscope and studied
plant cells.
o From investigating and experimenting with
plants, projected plant parts are made of
cells!
o Discussed what he observed with his dear
friend, German scientist Theodor
Schwann.
1838
THEODOR SCHWANN
o Studied plant & animal cells, and was
intrigued by the similarities between the
two.
o From investigating and experimenting with
plant & animal cells, Schwann was able to
determine that all animals are made of
cells!
o Schwann published the 1st statement of
the cell theory: all living things are made of
cells and cell products!.
1839
RUDOLF VIRCHOW
o Based on his investigations and
experiments, he stated that all cells come
from preexisting cells, which is the 2nd part
of the cell theory: all existing cells are
produced by other living cells.
Key Note: Collectively, the concepts from Schleiden,
Schwann, and Virchow were summarized into what is
known as cell theory, which states the following:
1. All organisms are composed of one or more
cells.
2. Cells are the smallest and basic units of
1855 structure and function in organisms.
3. Cells arise from previously existing cells.
Photo credits: Schleiden- thedailygadener.com, Schwann- cmijournal.org, Virchow-wikipedia.org
ELABORATE IT!
Instruction: Complete the phrase below.
MAIN IDEAS
Your knowledge about cells came
from the discoveries of numerous
___________________.
Cell theory is an explanation of
______________.
EXTEND IT!
Instruction: Write a brief letter of appreciation to the proponents of cell theory as
a sign of recognizing their efforts and great work in Science. Sight implications
what could have happen if significant inventions/discoveries were not made
possible.
My Personal Letter of Appreciation
9
CHECKPOINT POST TEST
I. Instruction: Write the letter that corresponds to the correct
answer.
1. Rudolf Virchow observations helped to disprove the commonly held belief
of?
a. evolution c. spontaneous generation
b. existence of molecules d. atomic models
2. What invention led to the development of cell theory?
a. telescope c. microwave
b. computer d. microscope
3. Why do you think there were no significant development of the discovery
of cells on the 17th Century?
a. Scientists got lazy to work for additional contributions.
b. There were not enough funding to go on with the experiments.
c. World War ruined the timeline.
d. There were no microscopes available with higher magnification.
4. Matthias Schleiden _______________; Theodor Schwann______________
a. botanist; histologist c. inventor; taxonomist
b. botanist; physiologist d. zoologist; botanist
5. The first term used by scientists before the word “cell” was coined.
a. cyto c. cork
b. molecule d. animalcules
6. ___________ are made up of at least one cell. Which word best fits in the
blank?
a. all living things c. animals
b. plants d. atoms
7. Where do all cells come from?
a. cell division c. mutation
b. evolution d. pre-existing cells
10
8. Who was the first person who see cells under the microscope and give them a
name?
a. Leeuwenhoek c. Hooke
b. Schwann d. Schleiden
9. He discovered that all plants were made of cells, who contributed to the
development of cell theory.
a. Virchow c. Schleiden
b. Schwann d. Leeuwenhoek
10. He advanced the cell theory with his conclusion that cells could only come
from other cells.
a. Hooke c. Schleiden
b. Virchow d. Schwann
11. A single-celled organism that Leeuwenhoek referred as animalcules.
a. protozoa c. animals
b. plant d. bacteria
12. Which of the following scientists contributed to the cell theory?
a. Hooke, Schwann, Schleiden, Leeuwenhoek, Virchow
b. Leeuwenhoek, Schwann, Schleiden, Darwin, Hooke
c. Sheen, Shwann, Hooke, Leeuwenhoek, Virchow
d. Clooney, Hooke, Schleiden, Schwann, Darwin
13. Which of the following statement is NOT part of the cell theory?
a. Cell is the basic unit of structure and function in all living things.
b. Only animal cells are composed of cells
c. All cells are produced from other cells
d. All living things are composed of cells
14. The invention of microscope made it possible for people to discover and learn
about ______________.
a. plants c. skin
b. animals d. cells
15.Why microscopes are important in studying cells?
a. Most cells are very large c. Most cells are very small
b. Most cells move very quickly d. Most cells are dead
11
KEY TASK
12
Learning Competency:
STEM_BIO11/12-la-c-2
Describe the structure and function of major and subcellular
organelles.
Learning Objectives:
o Enumerate the parts and function of the various organelles in
the cell.
o Construct a 3D model of plant/animal cell using recyclable
materials.
o Uphold the value of collaboration as students compare cellular
organelles jobs similar to a function of a factory and its workers.
13
PRETEST
14
9.Which of these is a possible explanation for the presence of a rigid cell wall in
plants?
a. Plants remain exposed in temperature and thus require rigid cell walls to
protect themselves.
b. Plants are subjected to variations in osmotic pressure, and a cell wall
helps them against bursting or shrinking.
c. Plant cells have a rigid cell wall to protect themselves from grazing animals
d. Plant cells have a rigid cell wall to prevent the influx of waste material.
10. What happens to the proteins that are synthesized on free ribosomes in the
cytoplasm?
a. These proteins move through the Golgi apparatus and enter the in the
nucleus.
b. These proteins go through the Golgi apparatus and remain in the cytosol.
c. The proteins do not go through the Golgi apparatus and move into the
nucleus for processing.
d. The proteins stay in the cytosol, free roaming.
11. A centriole is an organelle that is:
a. present in the center of a cell’s cytoplasm
b. composed of microtubules and important for organizing the spindle fibers.
c. surrounded by a membrane
d. part of a chromosome
12. The rough endoplasmic reticulum is:
a. an intracellular double-membrane system to which ribosomes are
attached.
b. an intracellular membrane that is studded with microtubular structures
c. a membranous structure found within mitochondria
d. only found in prokaryotic cells
13. Lysosomes are formed by budding from which cellular organelle?
a. smooth endoplasmic reticulum c. rough endoplasmic reticulum
b. golgi apparatus d. nucleus
15
16
Instruction: Make a word search and complete the puzzle. See the
word bank for possible answers.
WORD BANK
o HOOKE
o REPRODUCE
o GROW
o SCHWANN
o CELL
o VIRCHOW
o SCHLEIDEN
o RESPOND
o LEUWENHOEK
o ONE
ACROSS:
1. German scientist that discovered that animals were made of cells.
5. Scientist who discovered single-celled organism.
7. The minimum number of cells needed to be considered living.
8. German scientist that discovered cells come from preexisting cells.
DOWN:
2. Scientist who discovers cells while looking at the piece of cork.
3. German scientist that discovered plants were made of cells.
4. When a living thing react to a certain change.
6. Living things experienced from infants to adults.
17
EXPLORE IT!
Instruction: Compare and contrast plant cell and animal cell. Put
a check mark if the organelle is present and a wrong mark if the
organelle is absent. Provide the function of the organelles to
complete the table.
18
In this lesson, you will explore the world of eukaryotic cells, what
how these structures work to
common structures they share, and
provide a function that is very essential to every forms of life.
Cytoplasm
Function:
§ Fills the space between the nucleus
and the cell membrane
§ Holds the organelles in place
Structure:
Cytoplasm
§ Composed of jelly-like material
called cytosol, consisting mainly of
water.
Function:
§ Storehouse of the genetic
information in the form of DNA
§ Control center of the cell
Chromatin
Structure:
§ Nuclear envelope- encloses the
Pore DNA
Nucleolus § Nuclear pores- allow large
molecules to pass between the
Nuclear
Envelope nucleus and cytoplasm.
§ Nucleolus-dense region where
small organelles essential for
making proteins assemble.
Photo credit: Cytoplasm-genome.gov, Nucleus- ck12.org
21
Function:
§ Build proteins polymers from
amino acid monomers
Structure:
§ Small beadlike structure
Endoplasmic reticulum
Function:
§ Facilitates the manufacture of protein
Structure:
§ Rough ER- studded with ribosomes
-makes proteins
§ Smooth ER- not studded with ribosoms
- makes lipids
Rough endoplasmic
reticulum
Smooth endoplasmic
reticulum
Photo credit: Ribosome-genome.gov, Endoplasmic reticulum-dynamicscience.com.au
22
Golgi Apparatus
Function:
§ Transports and modify products
from endoplasmic reticulum.
Structure:
§ Made up of vesicles that act as
storage, transport, and
secretory.
Vacuole
Function:
§ Storage of materials which
includes water, food
molecules, organic ions, and
enzymes
§ Strengthens the cell and
supports entire plant by
making it erect
Structure:
§ Transparent sac
§ Larger in plants than in
animals
Photo credit: Ribosomes-vectorstock.com, Vacuole-
medium.com
23
Lysosome
Function:
§ Digest food within cells
§ Break down damaged and worn
out cell parts
Structure:
§ Round-shaped membrane-
bound structure containing
enzyme called lysozyme
Peroxisome
Function:
§ Break down complex
molecules into smaller
molecules
Structure:
§ Single membrane that
contains oxidative enzymes
such as catalase and urate
oxidase.
24
Energy-processing Organelles
Mitochondria
Function:
§ Cell’s energy factory
§ Makes ATP from cellular
respiration
Structure:
§ Bean shaped with two membranes
§ Inner membrane consists of folds
that increases surface area
Chloroplast
Function:
§ Convert solar energy to
chemical energy
§ Carry out photosynthesis
Structure:
§ Thylakoid- sacs in the
chloroplast membrane
§ Granum- stack of thylakoid
§ Stroma- liquid portion of the
chloroplast
25
Function:
§ Provides shape and structure of
the cell
§ Helps move organelles around
the cell
Structure:
§ Microtubule- thickest, serves as
anchorage for the membrane-
bound organelles
§ Intermediate- ropelike in
appearance, gives cell tensile
strength and the ability to
stretch without breaking apart
§ Microfilament- thinnest, provide
protective meshwork under the
plasma membrane
Centrioles
Function:
§ Help coordinate cell division
through forming spindle fibers
Structure:
§ Cylinder-shaped
§ Made up of nine triplets of
microtubule
26
Instruction: Read each riddle below and identify the organelle that is
“speaking”.
WHO AM I?
1. I am found only in 2. I store molecules 3. I am the cell’s 4. I act like a 5. I absorb light
plant cells, I am made or send them into the transport system digestive system in energy from the sun
of a specialized cytosol or out of the there are two of me an animal cell. I and use it convert
substance called cell. I process the the rough and the contain enzymes carbon dioxide and
cellulose. I provide proteins produced by smooth. The rough that breakdown water to sugar and
support and the endoplasmic type has ribosomes wastes and other oxygen. I am not
protection and give reticulum and attached. I am the. materials. I am the. found in animal cells,
plants their shape. I ribosomes. I am the. I am the.
am the. ______________________
_______________________ _______________ _______________________
________________________
6. I am the brain of 7. I am composed 8. I am the jelly-like 9. I am found only
the cell and I control of a network of fluid inside the cell. in an animal cell, I
all the activities of the protein filaments I provide an area of help organize cell
cell. I am located in that help maintain movement for all division. I look
the cytosol, but you cell shape and cell the dissolved good with the
would not find me in movement. I am molecules that triplets of
prokaryotic cells. I the. keep the cell microtubules that
am the. ______________________ working. I am the. composed me. I am
_ the.
_________________________ ______________________
______________________
10. I am very large 11. When a cell 12. We build proteins 13. I contain the 14. I am a thin
in plant cells, and I needs energy. I in the cells. We can be enzyme catalase. I protective layer
store water, food, take in nutrients, found in several breakdown hydrogen around the cell, but
and wastes. I help break them down, places in the cell, peroxide in the cell I am not one solid
support the plant. and supply energy including in the environment. I am piece. I have tiny
When I start to to the cell. I can cytosol and on the the. openings that allow
shrink due to lack also convert stored endoplasmic materials to pass in
of water, the plant energy in the cell to reticulum. We are. ________________________ and out of the cell. I
may wilt. I am the. food. I am a. am the.
________________________
______________________ ______________________ ______________________
27
ELABORATE IT!
“Organelles do the work to keep the cell alive. To keep you alive!”
________________________________________________________________
Title
_________________________________________________________________
________________________________________________________________________
________________________________________________________________________
________________________________________________________________________
________________________________________________________________________
________________________________________________________________________
________________________________________________________________________
________________________________________________________________________
________________________________________________________________________
________________________________________________________________________
________________________________________________________________________
________________________________________________________________________
________________________________________________________________________
28
EXTEND IT!
Instruction: Compare the cell to a factory. State what organelle corresponds to the
function of a factory icon given below.
ASSEMBLY LINE PACKAGING DEPARTMENT DELIVERY TEAM
CLEANING CREW POWER PLANT
29
POST TEST
CHECKPOINT
30
31
KEY TASK
Instruction: Construct a 3D model of plant/animal cell using
indigenous/recyclable materials. Follow the scoring guide below.
Poor Fair Good Exceeds
(6 pt.) (8 pts.) (10 pts.) (15pts.)
Cell Model looks like Model cannot be Model clearly Model clearly
Structure generalized cell. No identified as plant or represents an represents an
distinguishing factors of animal cell, because it animal or plant animal or animal
/Cell Type
a plant or animal cell. has characteristics of cell, with 1 to 2 cell.
both a plant and cell part mistakes
animal cell.
Organelle 0-5 of cell organelle 6-9 of cell organelle 10-12 cell All cell organelle
function functions are described functions are organelle functions are
and defined clearly described and functions are described and
and/or poorly defined clearly. described and defined clearly.
described, there are defined clearly.
errors when being
defined.
Cell details The work is done with The work was done The work was The work done
poor effort. Cell parts with good effort. done with good exceeds all
and organelles are not Most of the cell parts effort. Most of the expectations. The
detailed, they look like and organelles are cell parts and cell parts and
unformed and/or distinguishable. Most organelles are organelles are
misshapen making them of the organelles and distinguishable. easily
indistinguishable. cell parts are detailed Most of the distinguishable.
accurately. organelles and cell All organelles and
parts are detailed cell parts and
accurately. accurately.
Labeled 0-5 of cell organelles 6-9 of cell organelles 10-12 cell All cell organelles
organelles labeled and/or errors of are labeled and organelles are are labeled and
labeling and placement placed correctly. labeled and placed placed correctly.
of the organelles. correctly.
Creativity Not very appealing. Contains students Eye catching.
Lacks original artwork. Limited use of own writing and Great use of
Not students own creative materials. drawing. Lots of colors, texture,
drawing/writing/crafts. Not a lot of colors, shapes, and shapes. Artwork is
Messy. Lacks color. color/shapes/design. appealing design. the students own
Shows the student & is neat. Writing
spent time is easy
creating an artistic
piece.
Appearance Not in required format Project is damaged, Project is correct Project is of
and/or submitted late. poorly presented. size, clean and exceptional
Pieces/items falling or Was possibly neatly displayed. quality and
hanging off. submitted later than No items falling presentation.
original due date. off. Submitted on Nothing hanging
Some items possibly due date. or falling off.
falling off. Submitted on time.
32
Answer Key (Lesson 1):
What I Know (Pretest) What’s New What I have
learned
1. A 6. A 11. A 1. Yeast / 1. scientist
2. A 7. C 12. A 2. Corona Virus X 2. life
3. B 8. B 13. A 3. Seaweed /
4. D 9. B 14. C 4. Mushroom /
5. D 10.B 15. A 5. Corals /
6. Bacteria /
Posttest
1. C 6. A 11. A
2. D 7. D 12. A
3. D 8. C 13. B
4. B 9. C 14. D
5. D 10.A 15. C
Posttest
1. B 6. C 11. B
2. C 7. B 12. C
3. C 8. D 13. A
4. B 9. B 14. D
5. D 10.D 15. B
33
References
34
35