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group IB

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coinage metals copper, silver, gold
• only reddish colored metal
• third most malleable metal
copper • excellent conductor of heat (surpassed only by silver and gold),
electricity (surpassed by silver)
• present on hemocyanin and cytochrome oxidase
cuprous ion and cupric ion copper forms two series of salts, what are those?
• Cu+
• readily undergo disproportionation
cuprous ion
• water insoluble
• all are white except Cu2S and CuO
Cu2S; copper (I) sulfide Black
Cu2O, Copper oxide brickred
• Cu2+
cupric ion • maximum oxidation state

Bronze and Brass important alloys


bronze Cu + Sn
Brass Cu+ Zn
protein precipitant, and enhances utilization of atom Pharmacologic action
Toxicity excessive amount of one compound
Wilson's disease toxicity of copper
Penicillamine (cuprimine ) Antidote for Wilson's disease
Menkes disease Deficiency of Copper
• C4H6As6Cu4O16
copper aceto-arsenite • Paris green
• use: insecticide
• CuSO4• 5H2O
• blue vitriol, blue stone, roman vitriol, saltburg
• antidote for phosphorus poisoning (PP)
• stimulates vomiting reflex (emetic) and hands utilization of iron
cupric sulfate
• algaecide and fungicide in swimming pools
• component of benedict's solution, , Fehling Solution ( Fehling's
A), Barfoed's Solution
• Bordeaux (fungicide) mixture -> cupric sulfate+ lime CaO
• very soft, ductile, and malleable metal
• fine silver 99.9% pure too soft
silver • usually alloyed to give strength while preserving ductility and
beauty of metal
• sterling silver-> 92.5% Ag7.5% Cu
Protein precipitant pharmacological action of Ag
Oligodynamic Action of Ag ability to inhibit bacterial growth in small concentration
Argyria (Silver poisoning) toxicity of silver
NaCl, NSS Antidote for Angyria
• AgNO3
• lunar caustic lapisinfernlularis (caustic pencil)
• component of inedible ink
silver nitrate • use for treatment of warts
• 1% of thalamic solution-> prophylaxis for gonorrhea of opthalmia
neonatorum
- Replaced by Erythromycin as current therapy

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group IB
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• silver nitrate pencil, moulded silver nitrate, fused silver nitrate,
lunar caustic
toughened silver nitrate
• use: removal of warts for canker sores in the mouth
• "toughened'-> 5% AgCl
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silver proteinate .
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• Au
• king of all metals
• most malleable metal
• best conductor of electricity
• precious metal; expensive
Gold • !can be dissolved by:
- Agua Regia -> 3parts HCl : 1part of HNO3
Gold------------> Chloroauric acid
- Selenic Acid-> only single acid that can dissolve Au
Gold------------> Auric selenate
- Purple of Cassius: colloidal gold + stannous hydroxide
• Sn (OH)2
• use for treatment of rheumatical arthritis (DMARDs- Dis-
ease-Modifying-Antirheumatic- Disease)
- Aurothioglucose. AuSC6H11O5
Gold Compounds
- 1M; 50Au
- Gold Sodium Thiomalate. (Myochysine / Aurothiomalate)
- 1M; 50 Au
- Auranofin (Rioara )

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