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Test Bank for Anatomy and Physiology 4th Edition by Marieb

Test Bank for Anatomy and Physiology 4th Edition


by Marieb

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Chapter 6 Bones and Skeletal Tissue

6.1 Matching Questions

Figure 6.1

Using Figure 6.1, match the following bone types with the numbered structure:

1) Bone 1.
Answer: Flat
Diff: 1 Page Ref: 154; Fig. 6.2

2) Bone 2.
Answer: Long
Diff: 1 Page Ref: 154; Fig. 6.2

3) Bone 3.
Answer: Flat
Diff: 1 Page Ref: 154; Fig. 6.2

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4) Bone 4.
Answer: Irregular
Diff: 1 Page Ref: 154; Fig. 6.2

5) Bone 5.
Answer: Long
Diff: 1 Page Ref: 154; Fig. 6.2

6) Bone 6.
Answer: Sesamoid
Diff: 2 Page Ref: 154; Fig. 6.2

7) Bone 7.
Answer: Short
Diff: 1 Page Ref: 154; Fig. 6.2

Figure 6.2

Using Figure 6.2, match the following:

8) Compact bone.
Answer: C
Diff: 1 Page Ref: 157; Fig. 6.4

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9) Location of the epiphyseal line.
Answer: B
Diff: 1 Page Ref: 157; Fig. 6.4

10) Area where yellow marrow is found.


Answer: D
Diff: 1 Page Ref: 157; Fig. 6.4

11) Epiphysis of the bone.


Answer: A
Diff: 2 Page Ref: 157; Fig. 6.4

Match the following:

A) Osteoporosis
B) Paget's disease
C) Osteomalacia

12) Bones are porous and thin but bone composition is normal.
Diff: 2 Page Ref: 171

13) Bone formed is poorly mineralized and soft. Deforms on weight bearing.
Diff: 2 Page Ref: 171

14) Abnormal bone formation and reabsorption.


Diff: 2 Page Ref: 172

Answers: 12) A 13) C 14) B

Match the following:

A) Greenstick
B) Spiral
C) Comminuted

15) An incomplete fracture or cracking of the bone without actual separation of the parts.
Common in children.
Diff: 1 Page Ref: 170; Tbl. 6.2

16) Bone fragments into many pieces.


Diff: 1 Page Ref: 170; Tbl. 6.2

17) Common sports fracture resulting from a twisting force.


Diff: 1 Page Ref: 170; Tbl. 6.2

Answers: 15) A 16) C 17) B

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Match the following:

A) Canaliculi
B) Osteoblasts
C) Osteoclasts
D) Lamellae
E) Endosteum

18) The lining of the marrow cavity.


Diff: 1 Page Ref: 160

19) Cells that can dissolve the bony matrix.


Diff: 1 Page Ref: 159

20) Layers of bone matrix.


Diff: 1 Page Ref: 160

21) Small channels that radiate through the matrix of bone.


Diff: 1 Page Ref: 160

22) Cells that can build bony matrix.


Diff: 1 Page Ref: 158

Answers: 18) E 19) C 20) D 21) A 22) B

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Match the following:

A) Appositional growth
B) Epiphyseal plate
C) Epiphyseal line
D) Diaphysis
E) Chondrocytes

23) The cells responsible for the early stages of endochondral ossification.
Diff: 2 Page Ref: 152, 162

24) The growth pattern of bone in which matrix is laid down on the surface.
Diff: 2 Page Ref: 154

25) The area of long bones where cartilage cells are replaced by bone cells.
Diff: 2 Page Ref: 162-163

26) The appearance of this structure signals the end of bone growth.
Diff: 2 Page Ref: 163

27) Area where bone longitudinal growth takes place.


Diff: 2 Page Ref: 164

Answers: 23) E 24) A 25) D 26) C 27) B

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Match the following:

A) Coxal bone
B) Vertebrae
C) Femur
D) Occipital bone

28) Ischial spine


Diff: 2 Page Ref: 159, Tbl. 6.1

29) Foramen
Diff: 2 Page Ref: 159, Tbl. 6.1

30) Facet
Diff: 2 Page Ref: 159, Tbl. 6.1

E) Mandible
31) Ramus
Diff: 2 Page Ref: 159, Tbl. 6.1

32) Trochanter
Diff: 2 Page Ref: 159, Rbl. 6.1

Answers: 28) A 29) D 30) B 31) E 32) C

6.2 True/False Questions

1) Hematopoiesis refers to the formation of blood cells within the red marrow cavities of certain
bones.
Answer: TRUE
Diff: 1 Page Ref: 155

2) Compact bone is replaced more often than spongy bone.


Answer: FALSE
Diff: 1 Page Ref: 166

3) Bones are classified by whether they are weight bearing or protective in function.
Answer: FALSE
Diff: 1 Page Ref: 154

4) The periosteum is a tissue that serves only to protect the bone because it is not supplied with
nerves or blood vessels.
Answer: FALSE
Diff: 1 Page Ref: 156-157

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5) Short, irregular, and flat bones have marrow cavities in order to keep the weight of the bones
light.
Answer: FALSE
Diff: 1 Page Ref: 156

6) The structural unit of compact bone (osteon) resembles the growth rings of a tree trunk.
Answer: TRUE
Diff: 1 Page Ref: 160

7) The term osteoid refers to the organic part of the matrix of compact bones.
Answer: TRUE
Diff: 1 Page Ref: 160-161

8) Sixty-five percent of the mass of bone is a compound called hydroxyapatite.


Answer: TRUE
Diff: 1 Page Ref: 162

9) All bones stop growing by the end of adolescence.


Answer: FALSE
Diff: 2 Page Ref: 164

10) An osteon contains osteocytes, lamellae, and a central canal, and is found in compact bone
only.
Answer: TRUE
Diff: 1 Page Ref: 160

11) The trabeculae of spongy bone are oriented toward lines of stress.
Answer: TRUE
Diff: 2 Page Ref: 160

12) The hormone that is primarily involved in the control of bone remodeling is the parathyroid
hormone.
Answer: FALSE
Diff: 2 Page Ref: 166

13) Each consecutive bone lamella has collagen fibers that wrap in alternating directions.
Answer: TRUE
Diff: 2 Page Ref: 160

14) Cartilage has a flexible matrix that can accommodate mitosis of chondrocytes.
Answer: TRUE
Diff: 1 Page Ref: 154

15) Closure of the epiphyseal plate stops all bone growth.


Answer: FALSE
Diff: 2 Page Ref: 163-164

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6.3 Multiple-Choice Questions

1) The structure of bone tissue suits the function. Which of the following bone tissues is adapted
to support weight and withstand tension stress?
A) spongy bone
B) irregular bone
C) compact bone
D) trabecular bone
Answer: C
Diff: 1 Page Ref: 156-158

2) Yellow bone marrow contains a large percentage of ________.


A) fat
B) blood-forming cells
C) elastic tissue
D) Sharpey's fibers
Answer: A
Diff: 1 Page Ref: 156

3) The cell responsible for secreting the matrix of bone is the ________.
A) osteocyte
B) osteoblast
C) osteoclast
D) chondrocyte
Answer: B
Diff: 1 Page Ref: 158; Fig. 6.5

4) What kind of tissue is the forerunner of long bones in the embryo?


A) elastic connective tissue
B) dense fibrous connective tissue
C) fibrocartilage
D) hyaline cartilage
Answer: D
Diff: 1 Page Ref: 162-163

5) What can a deficiency of growth hormone during bone formation cause?


A) inadequate calcification of bone
B) decreased osteoclast activity
C) decreased proliferation of the epiphyseal plate cartilage
D) increased osteoclast activity
Answer: C
Diff: 1 Page Ref: 165

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6) A fracture in the shaft of a bone would be a break in the ________.
A) epiphysis
B) metaphysis
C) diaphysis
D) articular cartilage
Answer: C
Diff: 1 Page Ref: 156

7) The term diploë refers to the ________.


A) double-layered nature of the connective tissue covering the bone
B) fact that most bones are formed of two types of bone tissue
C) internal layer of spongy bone in flat bones
D) two types of marrow found within most bones
Answer: C
Diff: 1 Page Ref: 156

8) Which of the following is a bone marking name that indicates an armlike bar of bone?
A) meatus
B) ramus
C) foramen
D) fossa
E) epicondyle
Answer: B
Diff: 1 Page Ref: 159; Tbl. 6.1

9) What causes osteoporosis?


A) poor posture
B) Osteoclasts out-pace osteoblasts due to low hormone production of the ovaries.
C) heritage such as African or Mediterranean
D) abnormal PTH receptors
Answer: B
Diff: 2 Page Ref: 171-172

10) Ossification of the ends of long bones ________.


A) is a characteristic of intramembranous bone formation
B) involves medullary cavity formation
C) is produced by secondary ossification centers
D) takes twice as long as diaphysis ossification
Answer: C
Diff: 1 Page Ref: 163

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11) Which structure allows the diaphysis of the bone to increase in length until early childhood?
A) lacunae
B) Haversian system
C) epiphyseal plate
D) epiphyseal line
Answer: C
Diff: 2 Page Ref: 163-164

12) Which of the following is the single most important stimulus for epiphyseal plate activity
during infancy and childhood?
A) parathyroid hormone
B) calcium
C) growth hormone
D) thyroid hormone
Answer: C
Diff: 2 Page Ref: 165

13) Which of the following is not a function of the skeletal system?


A) support
B) storage of minerals
C) production of blood cells (hematopoiesis)
D) communication
Answer: D
Diff: 1 Page Ref: 154-155

14) What is the structural unit of compact bone?


A) osseous matrix
B) spongy bone
C) lamellar bone
D) the osteon
Answer: D
Diff: 1 Page Ref: 160

15) Bones are covered and lined by a protective tissue called periosteum. The inner (osteogenic)
layer consists primarily of ________.
A) cartilage and compact bone
B) marrow and osteons
C) osteoblasts and osteoclasts
D) chondrocytes and osteocytes
Answer: C
Diff: 1 Page Ref: 156-158

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16) The periosteum is secured to the underlying bone by dense connective tissue called
________.
A) Volkmann's canals
B) a bony matrix with hyaline cartilage
C) perforating (Sharpey's) fibers
D) the struts of bone known as spicules
Answer: C
Diff: 1 Page Ref: 157

17) The canal that runs through the core of each osteon (the Haversian canal) is the site of
________.
A) cartilage and interstitial lamellae
B) adipose tissue and nerve fibers
C) yellow marrow and spicules
D) blood vessels and nerve fibers
Answer: D
Diff: 1 Page Ref: 160

18) The resilience of bone is primarily due to which of the following?


A) amount of mineral salts in the bone
B) presence of osteoblasts in the bone
C) sacrificial bonds in or between collagen molecules
D) amount of mineral salt and protein in the bone
Answer: C
Diff: 2 Page Ref: 160-161

19) For intramembranous ossification to take place, which of the following is necessary?
A) A bone collar forms around the cartilage model.
B) An ossification center forms in the fibrous connective tissue.
C) The cartilage matrix begins to deteriorate.
D) A medullary cavity forms.
Answer: B
Diff: 1 Page Ref: 163-64; Fig. 6.9

20) The process of bones increasing in width is known as ________.


A) closing of the epiphyseal plate
B) epiphyseal plate closure
C) appositional growth
D) concentric growth
Answer: C
Diff: 1 Page Ref: 164

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21) Bones are constantly undergoing resorption for various reasons. Which of the following cells
accomplishes this process?
A) osteoclast
B) osteocyte
C) osteoblast
D) stem cell
Answer: A
Diff: 1 Page Ref: 166

22) Which hormone increases osteoclast activity to release more calcium ions into the
bloodstream?
A) calcitonin
B) thyroxine
C) parathyroid hormone
D) estrogen
Answer: C
Diff: 1 Page Ref: 166

23) What is absolutely required for bone growth or healing from a fracture?
A) dietary intake of calcium and vitamin D
B) osteocytes
C) osteoclasts
D) osteoblasts
Answer: D
Diff: 2 Page Ref: 158

24) Wolff's law is concerned with ________.


A) vertical growth of bones being dependent on age
B) the thickness and shape of a bone being dependent on stresses placed upon it
C) the function of bone being dependent on shape
D) the diameter of the bone being dependent on the ratio of osteoblasts to osteoclasts
Answer: B
Diff: 2 Page Ref: 167

25) Cranial bones develop ________.


A) from cartilage models
B) within fibrous membranes
C) from a tendon
D) within osseous membranes
Answer: B
Diff: 2 Page Ref: 163

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26) Which of the following glands or organs produces hormones that tend to decrease blood
calcium levels?
A) pineal gland
B) thyroid
C) parathyroid
D) spleen
Answer: B
Diff: 2 Page Ref: 166

27) Cartilage grows in two ways, appositional and interstitial. What is appositional growth?
A) growth at the epiphyseal plate
B) the secretion of new matrix against the external face of existing cartilage
C) along the edges only of existing osteons, making each osteon larger
D) the lengthening of hyaline cartilage
Answer: B
Diff: 2 Page Ref: 154

28) Which of the following statements best describes interstitial growth?


A) Growth occurs in the lining of the long bones.
B) Fibroblasts give rise to chondrocytes that differentiate and form cartilage.
C) Unspecialized cells from mesenchyme develop into chondrocytes, which divide and form
cartilage.
D) Chondrocytes in the lacunae divide and secrete matrix, allowing the cartilage to grow from
within.
Answer: D
Diff: 2 Page Ref: 154

29) In the epiphyseal plate, cartilage grows ________.


A) by pulling the diaphysis toward the epiphysis
B) by pushing the epiphysis away from the diaphysis
C) from the edges inward
D) in a circular fashion
Answer: B
Diff: 2 Page Ref: 164

30) The structural unit of spongy is called ________.


A) osteons
B) lamellar bone
C) trabeculae
D) osseous lamellae
Answer: C
Diff: 2 Page Ref: 160

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31) Osteogenesis is the process of ________.
A) making a cartilage model of the fetal bone
B) bone destruction to liberate calcium
C) bone formation
D) making collagen fibers for calcified cartilage
Answer: C
Diff: 2 Page Ref: 162

32) Lengthwise, long bone growth during infancy and youth is exclusively through ________.
A) interstitial growth of the epiphyseal plates
B) the secretion of bone matrix into the medullary cavity
C) differentiation of osteoclasts into osteocytes
D) calcification of the matrix of the zone underlying articular cartilage
Answer: A
Diff: 2 Page Ref: 163-164

33) Growth of bones is controlled by a symphony of hormones. Which hormone is of greatest


importance for bone growth during infancy and childhood?
A) thyroid hormone
B) somatomedins
C) growth hormone
D) prolactin
Answer: C
Diff: 2 Page Ref: 165

34) In some cases the epiphyseal plate of the long bones of children closes too early. What might
be the cause?
A) overproduction of thyroid hormone
B) elevated levels of sex hormones
C) too much vitamin D in the diet
D) osteoblast activity exceeds osteoclast activity
Answer: B
Diff: 2 Page Ref: 165

35) Normal bone formation and growth are dependent on the adequate intake of ________.
A) calcium, phosphate, and vitamin D
B) potassium, phosphate, and vitamin D
C) sodium, calcium, and vitamin E
D) vitamin D, phosphate, and chloride
Answer: A
Diff: 3 Page Ref: 187

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36) What tissue forms the model for endochondrial ossification?
A) cartilage
B) membranes
C) fascia
D) bone
Answer: A
Diff: 1 Page Ref: 162

6.4 Fill-in-the-Blank/Short Answer Questions

1) Blood cell formation is called ________.


Answer: hematopoiesis
Diff: 1 Page Ref: 155

2) A bone embedded in a tendon is called a(n) ________ bone.


Answer: sesamoid
Diff: 1 Page Ref: 155

3) A central (Haversian) canal may contain arteries, veins, capillaries, lymph vessels, and
________ fibers.
Answer: nerve
Diff: 1 Page Ref: 160

4) A long bone forms by a process known as ________ ossification.


Answer: endochondral
Diff: 1 Page Ref: 162

5) What term describes in growth in the diameter of long bones?


Answer: Appositional
Diff: 1 Page Ref: 164-165

6) What are multinucleated cells that destroy bone called?


Answer: Osteoclasts
Diff: 1 Page Ref: 159; Fig. 6.5

7) What is a disease of the bone in which bone reabsorption outpaces bone deposit, leaving the
person with thin and often very fragile bones?
Answer: Osteoporosis
Diff: 1 Page Ref: 171-172

8) A round or oval hole through a bone that contains blood vessels and/or nerves is called a(n)
________.
Answer: foramen
Diff: 1 Page Ref: 158; Tbl. 6.1

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9) List the steps in the repair process of a simple fracture.
Answer: Hematoma formation, fibrocartilaginous callus formation, bony callus formation, and
remodeling.
Diff: 1 Page Ref: 168-169

10) What is found in a Haversian canal?


Answer: Blood vessels and nerve fibers.
Diff: 1 Page Ref: 160

11) Several hormones control the remodeling of bones. Which two respond to changing blood
calcium levels?
Answer: PTH and calcitonin are the major determinants of whether and when remodeling will
occur in response to changing blood calcium.
Diff: 2 Page Ref: 166

12) Why are the bones of young children much more flexible than those of the elderly?
Answer: Bones of children are not completely calcified, with a higher ratio of more flexible
organic fibers. Bones in the elderly are more completely calcified, which gives the characteristic
of rigidity.
Diff: 2 Page Ref: 163-164

13) Bones appear to be lifeless structures. Does bone material renew itself?
Answer: Bone only appears lifeless in gross anatomy. Microscopically, bone is full of cells and
blood vessels that maintain and renew bone tissue. Approximately 5% to 7% of our bone mass is
recycled each week. Up to 0.5 g of calcium may enter or leave the bones each day, depending on
the negative feedback hormonal mechanism and gravitational forces.
Diff: 3 Page Ref: 165-168

14) Compare the function of the organic materials in the bone matrix with the function of the
inorganic materials in the matrix.
Answer: The organic matrix contributes to the bone structure and its tensile strength, while the
inorganic matrix contributes to hardness and resistance to compression.
Diff: 3 Page Ref: 160-162

15) What are the differences between the diaphysis and the epiphyses of long bones?
Answer: Diaphyseal bone is composed almost entirely of compact bone (except in irregular and
short bones), while the epiphyses are composed almost entirely of spongy bone. The epiphyses
are on the ends of the bone; the diaphysis is the "shank" of the bone. The diaphysis in long bones
has a large medullary cavity, whereas the epiphyses do not.
Diff: 3 Page Ref: 156

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16) Describe how oxygen is carried from outside a bone to an individual osteocyte.
Answer: Blood vessels enter through the periosteum into a perforating canal. The vessel may
follow along the axis of the bone through a central canal. Osteocytes have long, almost dendritic-
like extensions or arms that reach out through tiny holes called canaliculi. The canaliculi connect
one cell to another and to the central canal. Oxygen leaves the blood vessel in the central canal
and travels through the canaliculi from cell to cell until it reaches the cell in question.
Diff: 3 Page Ref: 160

17) How is the beginning of intramembranous ossification different from endochondral


ossification?
Answer: Intramembranous ossification starts in connective tissue from mesenchymal cells that
become osteoblasts. These osteoblasts cluster together into an ossification center. Endochondral
ossification starts with a hyaline cartilage "template." Mesenchymal cells become osteoblasts and
begin forming bone around the cartilage.

Diff: 3 Page Ref: 162-163

18) If your doctor notices a marked decrease in calcium ion levels in your blood, what gland
might he suspect is not functioning properly and why?
Answer: The parathyroid gland normally responds to low calcium ion levels in the blood and
releases PTH, which mobilizes osteoclasts to step up bone destruction, releasing more calcium
into the bloodstream. Persistent low blood calcium level therefore implies insufficient PTH,
suggesting injury or failure of the parathyroid glands.
Diff: 1 Page Ref: 166-167

6.5 Clinical Questions

1) Alice and James adopted a 3-year-old child from a developing country. They noticed that her
legs were bowed and there were some deformities in her cranial and pelvic bones. They brought
her to a physician for a diagnosis. What was the diagnosis, and what was the treatment for the
disorder?
Answer: The child most likely has rickets, a condition caused by poor diet, especially one
deficient in vitamin D. The parents were told to increase her intake of calcium and vitamin D and
to make sure that she gets some sunshine every day.
Diff: 3 Page Ref: 171

2) Emily, a 64-year-old formerly obese woman who successfully lost over 100 pounds, was
brought to the hospital suffering pain in her legs, and an X-ray revealed that she had a simple
fracture in her right femur and a crack in her left tibia. Other tests revealed that her bones were
brittle and porous. What might have happened to Emily, and what advice would she have been
given by the physician?
Answer: Emily has osteoporosis, a debilitating bone disease that strikes more women than men
after age 45-50. The bones become weak and brittle due to osteoclast out pacing of osteoblast in
the bone. Emily has been told that she needs to take supplements of Ca, Vitamin D, and do
weight baring exercise.
Diff: 3 Page Ref: 171-172

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3) A 75-year-old woman and her 9-year-old granddaughter were victims of a train crash. In both
cases, trauma to the chest was sustained. X rays of the grandmother revealed several fractured
ribs, but her granddaughter had none. Explain these different findings.
Answer: The child had more organic material in her bones, which allows bones to be more
flexible, while her grandmother's bones are extensively calcified, with little organic material, and
are probably thin due to osteoporosis.
Diff: 3 Page Ref: 164-165, 171

4) Johnny fractured the lower third of his right tibia in a skiing accident. The soft tissues in the
area were severely damaged and their surgical removal was necessary. After prolonged
immobilization, it was found that Johnny was healing very poorly. The explanation offered by
the orthopedic surgeon was that vascularization of the fracture site was still inadequate and good
healing was absolutely dependent upon an adequate blood supply. Describe how a long bone
receives its blood supply and trace the path of nutrient delivery to the osteocytes.
Answer: Long bones are nourished by nutrient arteries that frequently enter the shaft. Removal
of the soft tissues probably reduced the flow of blood to the affected area. The pathway requires
transport of nutrients from blood vessels to periosteum to Volkmann's canals to Haversian canals
to canaliculi to lacunae.
Diff: 3 Page Ref: 158-160

5) People who live in the north should take supplemental calcium with vitamin D. Explain why.
Answer: Vitamin D is manufactured by the skin using sunlight and is needed for absorption of
dietary calcium. People who live in the north where the winter months are severe may need
supplemental vitamin D because of the decreased amount of sunlight exposure.
Diff: 3 Page Ref: 166, 171

6) When does prevention of osteoporosis start?


Answer: The prevention of osteoporosis should begin with children. Parents need to provide
children with the opportunity to develop as much bone as they have inherited the ability to
develop. If people increase their peak bone mass as young adults, they will have additional
protection from osteoporotic fractures in the future.
Diff: 3 Page Ref: 172

7) If your elderly patient's blood calcium level is normal, does that mean the patient does not
have osteoporosis? Explain.
Answer: No. The level of calcium in the blood is expected to be normal, even in advanced cases
of osteoporosis. The calcium in the bones will be low, but that occurs in order to maintain a
normal blood calcium level.
Diff: 3 Page Ref: 171

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Test Bank for Anatomy and Physiology 4th Edition by Marieb

8) Mrs. Brown was outside on her patio cleaning windows when she fell off her step ladder and
fractured her right hip. She had emergency surgery with an open reduction and internal fixation
of the right hip. Three days postoperatively, she asks you if she will have trouble going through
airport security. What has prompted her concern?
Answer: Open reduction is the correction of the bone alignment through a surgical incision. It
may include internal fixation of the fracture with the use of rods, wire, screws, pins, or nails,
metal items that may trigger security alarms.
Diff: 3 Page Ref: 169

9) How can a tooth be moved in a bony socket during orthodontic treatment?


Answer: Because bone deposition and reabsorption can occur, and because bone responds to
mechanical stress (Wolff's law), a tooth can be moved. By applying slight pressure to a tooth, the
bone on the forward side will reabsorb, while the bone on the reverse side will be reformed.
Diff: 3 Page Ref: 166-167

10) Explain why swimming is not generally recommended as an exercise to prevent


osteoporosis.
Answer: Mechanical stress and gravity help to promote skeletal remodeling. Swimming is not
considered a weight-bearing exercise. The water, not bones, supports the body's weight while
swimming.
Diff: 2 Page Ref: 172

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