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Biology Science for Life with

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Biology: Science for Life with Physiology, 5e (Belk)
Chapter 8 DNA Detective: Complex Patterns of Inheritance and DNA Profiling

1) What pattern of inheritance results when the phenotype of a heterozygote is intermediate


between both homozygotes?
A) incomplete dominance
B) codominance
C) independent assortment
D) sex linkage
Answer: A
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.1

2) How is codominance expressed in an organism?


A) Both of the alleles in a heterozygote are expressed phenotypically in an individual.
B) Expression of two different alleles alternates from one generation to the next.
C) A heterozygote expresses an intermediate phenotype.
D) Offspring exhibit several different phenotypic expressions of a single trait.
Answer: A
Section: 8.1
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.1

3) What pattern of inheritance includes the AB blood type, in which both A and B alleles are
expressed?
A) incomplete dominance
B) codominance
C) independent assortment
D) sex linkage
Answer: B
Section: 8.1
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.1

4) What pattern of inheritance occurs when a light blue-colored flower results from a cross
between a dark blue-colored flower and a white-colored flower?
A) incomplete dominance
B) codominance
C) independent assortment
D) sex linkage
Answer: A
Section: 8.1
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.1

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5) What term describes phenotypic features that are coded for by several genes, such as eye color
in humans?
A) linked
B) polytrophic
C) polygenic
D) codominant
Answer: C
Section: 8.1
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.2

6) What pattern of inheritance occurs in the ABO blood system where there are three distinct
alleles in human populations?
Answer: Multiple allelism
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.3

7) Which blood type lacks the sugar found on the surface of red blood cells in other blood types?
A) type A
B) type B
C) type AB
D) type O
Answer: D
Section: 8.1
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.3

8) How would the pattern of inheritance for Rh factor be best described?


A) incomplete dominance
B) codominance
C) dominant-recessive
D) sex linkage
Answer: C
Section: 8.1
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.3

9) Which genotype doesn't have the Rh factor on the red blood cells?
A) Rh+ Rh+
B) Rh+ Rh-
C) Rh- Rh+
D) Rh- Rh-
Answer: D
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.3
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10) What parental blood type would not be able to produce a child with type O blood?
A) A
B) B
C) AB
D) O
Answer: C
Section: 8.1
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.3

11) What blood type would a child with the genotype IAi have?
A) A
B) B
C) AB
D) O
Answer: A
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.3

12) What blood type would a person who is homozygous recessive for all blood type alleles
have?
A) A
B) B
C) AB
D) O
Answer: D
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.3

13) How will people with the same blood type be related?
A) They are always unrelated.
B) They are always related.
C) They may or may not be related.
D) They always have both alleles in common but are not necessarily related.
Answer: C
Section: 8.1
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.3

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14) Which alleles are dominant to each other in blood type inheritance?
A) Alleles IA and i are dominant to the allele IB.
B) Alleles IB and i are dominant to the allele IA.
C) Alleles IA and IB are dominant to the allele i.
D) Alleles IA, IB, and i are codominant.
Answer: C
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.3

15) In human ABO blood types, what description applies to the alleles for A and B because
they're both expressed?
Answer: codominant
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.3

16) What pattern of inheritance results in Type AB blood?


A) polygenic inheritance
B) simple dominance
C) codominance
D) sex-linked recessive inheritance
Answer: C
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.3

17) What pattern of inheritance applies to a woman with type A blood who has the alleles IA and
i?
A) polygenic inheritance
B) simple dominance
C) codominance
D) sex-linked recessive inheritance
Answer: B
Section: 8.1
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.3

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18) What pattern of inheritance is occurring if one person in a population has two different
alleles of a particular gene and other people in the population have a third allele of this gene?
A) codominance
B) pleiotropy
C) incomplete dominance
D) multiple allelism
Answer: D
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.3

19) What genetic phenomenon occurs when a dominant allele has different effects between
heterozygous individuals and homozygous individuals?
A) codominance
B) continuous variation
C) incomplete dominance
D) polygenic inheritance
Answer: C
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.1

20) A patient with which blood type can receive blood from any donor?
A) type A
B) type B
C) type AB
D) type O
Answer: C
Section: 8.1
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.3

21) A patient with which blood type can donate blood to anyone?
A) type A
B) type B
C) type AB
D) type O
Answer: D
Section: 8.1
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.3

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22) A woman with type A blood and a man with type B blood have a baby with type O blood.
What are the genotypes of the woman and the man?
A) IAi and IBi
B) IAIA and IBi
C) IAi and IBIB
D) IAIA and IBIB
Answer: A
Section: 8.1
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.3

23) A woman with type AB blood and a man with type O blood have a child. Which type of
blood could the child have?
A) type A or type O
B) type B or type O
C) type AB or type O
D) type A or type B
Answer: D
Section: 8.1
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.3

24) What is the most common blood type in the U.S. population?
A) type O-
B) type B+
C) type AB-
D) type O+
Answer: D
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.3

25) What is the ability of a gene to cause multiple effects on a phenotype?


A) pleiotropy
B) codominance
C) polygenic inheritance
D) continuous variation
Answer: A
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.2

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26) What genetic information is indicated by describing a person as having hemophilia?
A) genotype
B) phenotype
C) genetic code
D) number of chromosomes
Answer: B
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.5

27) A person with hemophilia lacks the pleiotropic gene that codes for the protein called clotting
factor VIII. What effects will this have on a person with hemophilia?
A) The person will only have the symptom of lack of blood clotting (bleeding).
B) The person will always have the same symptoms as other hemophiliacs.
C) The person will have many other symptoms in addition to excessive bleeding.
D) The person will always have neurological problems.
Answer: C
Section: 8.1
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.5

28) In addition to excessive bleeding, persons with hemophilia may have excessive bruising,
pain, and swelling in the joints, vision loss, anemia, or neurological problems. What process
results from the effects of a single gene loss?
A) codominance
B) multiple allelism
C) pleiotropy
D) environmental effects
Answer: C
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.5

29) In addition to the environment, what genetic factor affects human bone size and structure?
A) polygenic inheritance
B) codominance
C) simple dominance
D) sex-linked recessive inheritance
Answer: A
Section: 8.1
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.2

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30) In which group can sex-linked traits be expressed?
A) males only
B) females only
C) either males or females
D) carriers only
Answer: C
Section: 8.2
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.5

31) Hemophiliacs have blood that does not coagulate well, and they often die at a young age.
The disease allele is recessive and X-linked. Which genetic possibilities can be predicted for the
offspring of a hemophiliac male and a nonhemophiliac female who is a carrier for the disease?
A) All children would be hemophiliac.
B) All females would be hemophiliac.
C) All males would be hemophiliac.
D) Some males and females could be hemophiliac.
Answer: D
Section: 8.2
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.5

32) Hemophilia is a genetic disease that has plagued the royal houses of Europe. The disease
allele is recessive and X-linked. Queen Victoria was a carrier, and her granddaughter Alexandra
married Nicholas II, the last czar of imperial Russia. Alexandra was a carrier for hemophilia;
Nicholas was normal. Their son, Alexis, was afflicted with the disease. Alexis and his four
sisters were killed in 1917. What genetic traits were possible for the four sisters?
A) None of the four sisters carried the hemophilia allele.
B) At least one of the sisters was a carrier of the allele.
C) All four sisters were carriers of the hemophilia allele.
D) At least one of the sisters had hemophilia like Alexis.
Answer: B
Section: 8.2
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.5

33) Hemophilia is an X-linked recessive allele causing a blood disorder. What are the chances
that a daughter of a normal man and a woman, who is heterozygous for the disease, will have
hemophilia?
A) 0%
B) 25%
C) 75%
D) 100%
Answer: A
Section: 8.2
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.5
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34) In humans, the allele for red-green color blindness is X-linked and recessive (Xr; the
dominant allele is called XR). A man with normal color vision marries a color-blind woman who
gives birth to a color-blind daughter. What can be inferred from this information?
A) The woman is XRXr.
B) The man must be a carrier for the color blindness allele.
C) The daughter must be heterozygous.
D) The man is probably NOT the father of the daughter.
Answer: D
Section: 8.2
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.5

35) Which characteristic applies to a normal individual who is a carrier for an X-linked trait such
as hemophilia?
A) The carrier is always female.
B) The carrier is homozygous for the recessive condition.
C) The carrier shows the recessive phenotype.
D) The carrier cannot have daughters who have the allele.
Answer: A
Section: 8.2
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.5

36) Y-linked genes include a gene that produces hairy ears. Which offspring would receive this
trait from a male with hairy ears?
A) only his sons
B) only his daughters
C) only his grandsons
D) all his children if the mother is a carrier
Answer: A
Section: 8.2
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.5

37) Which offspring will receive a harmful allele for a sex-linked trait from a man who carries
the allele?
A) all of his daughters
B) only half of his daughters
C) only half of his sons
D) all of his children
Answer: A
Section: 8.2
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.5

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38) In humans, what ordinarily determines the sex of the offspring?
A) autosomes carried by the egg cell
B) autosomes carried by the sperm cell
C) sex chromosome carried by the egg cell
D) sex chromosome carried by the sperm cell
Answer: D
Section: 8.2
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.4

39) In addition to autosomes, what is contained in a human sperm cell?


A) an X chromosome always
B) either an X or a Y chromosome
C) a Y chromosome always
D) both an X and a Y chromosome
Answer: B
Section: 8.2
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.4

40) What types and numbers of chromosomes are found in humans?


A) two pairs of sex chromosomes and 46 pairs of autosomes
B) two pairs of sex chromosomes and 22 pairs of autosomes
C) one pair of sex chromosomes and 46 pairs of autosomes
D) one pair of sex chromosomes and 22 pairs of autosomes
Answer: D
Section: 8.2
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.4

10
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41) What are the chances that a hemophiliac male and an unaffected female could have a baby
that is a hemophiliac male?
A) 0%
B) 25%
C) 50%
D) 75%
Answer: A
Section: 8.2
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.5

42) Because the bones thought to belong to the Romanov family were highly decayed, what type
of analysis was used by scientists to determine the gender of each deceased individual?
A) pelvic bone analysis only
B) DNA analysis of material that is specific to the Y chromosome
C) DNA analysis of material that is specific to the X chromosome
D) both pelvic bone analysis and DNA analysis
Answer: B
Section: 8.2
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.7

43) What is a family tree that is used to follow human matings that have already occurred?
A) test cross
B) karyotype
C) sex-linked record
D) pedigree
Answer: D
Section: 8.3
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.6

11
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44) Hemophilia is an X-linked recessive trait in humans. If phenotypically normal parents have
children without hemophilia, what information could be determined by a pedigree analysis?
A) Neither parent carries the hemophiliac allele.
B) None of their children is a carrier of the hemophilia allele.
C) None of their children could have hemophiliac children.
D) The exact genotypes of the parents or children
Answer: D
Section: 8.3
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.6

45) What information can be inferred about Queen Victoria based on a pedigree of the British
royal family?
A) She was the first royal family member with hemophilia.
B) All of her children were born with hemophilia.
C) She was the first royal family member with a mutation in a blood-clotting gene.
D) She inherited a mutation in a blood-clotting allele.
Answer: D
Section: 8.3
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.6

12
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46) On a pedigree chart, what symbol would represent a son who is affected by a genetic
disorder?
A) a shaded circle
B) a clear circle
C) a shaded square
D) a clear square
Answer: C
Section: 8.3
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.6

47) What does a half-shaded circle represent on a pedigree chart?


A) a female carrier
B) a female who does not have an allele for the genetic disorder represented
C) a male who is affected by the genetic disorder represented
D) a male carrier
Answer: A
Section: 8.3
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.6

48) Polydactyly is a dominant trait. What symbol on a pedigree chart would represent a male
who has polydactyly?
A) a half-shaded square
B) a shaded square
C) a half-shaded circle
D) a clear circle
Answer: B
Section: 8.3
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.6

49) Queen Elizabeth II of England is a descendant of Edward VII of England, who was the son
of Queen Victoria. Edward VII did not have hemophilia. Prince Philip, who is married to Queen
Elizabeth II, is a descendant of Alice, the daughter of Queen Victoria. Alice was a carrier of
hemophilia. However, Prince Philip does not have hemophilia. What can you infer about the
children of Queen Elizabeth II and Prince Philip?
A) None of the children could have the hemophilia allele.
B) Only the sons could have the hemophilia allele.
C) Only their daughter could have the hemophilia allele.
D) Any one of the children could have the hemophilia allele.
Answer: A
Section: 8.4
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.6

13
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50) Which type of forensic evidence was available for scientists studying the case of the
Romanovs?
A) fingerprint
B) toxicology
C) DNA
D) footprint
Answer: C
Section: 8.4
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.7

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51) Which member(s) of the Romanov family shared DNA sequences with England's Prince
Philip?
A) both the tsar and the tsarina
B) only the tsar
C) only the tsarina
D) neither the tsar nor the tsarina
Answer: C
Section: 8.4
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.6

15
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52) When comparing the DNA fingerprints of a parent and child, the parent's DNA fingerprint
will have which of the following genetic traits?
A) all of the DNA bands that the child has
B) more than half of the DNA bands that the child has
C) DNA bands that match those in the child's fingerprint and that aren't from the other parent
D) DNA bands that are very close to bands found in the child but do not match precisely
Answer: C
Section: 8.4
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.7

53) Why must DNA fragments be denatured during the polymerase chain reaction?
A) Taq polymerase breaks down when heated.
B) The repeated gene sequences are not present in double-stranded DNA.
C) The primer must bind to a single-stranded template to synthesize double-stranded DNA.
D) VNTRs have DNA sequences that vary in number.
Answer: C
Section: 8.4
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.7

54) What does the acronym VNTR mean?


A) variable number tandem repeats
B) varied nucleotides to repeat
C) volumes of nucleotide tandem repeats
D) variation of nucleotide terminal repeats
Answer: A
Section: 8.4
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.7

55) A DNA fingerprint of a suspect doesn't match a DNA fingerprint from a blood sample taken
at a crime scene. What can you conclude?
A) The suspect was never at the crime scene.
B) The blood sample was probably degraded or destroyed in some way.
C) There is no DNA in a blood sample.
D) The blood came from a different person, but the suspect may have been there.
Answer: D
Section: 8.4
Skill: Application/Analysis (Apply/Analyze)
Learning Outcome: 8.7

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56) Why do different people have different DNA fingerprints?
A) They have completely different kinds of VNTRs.
B) They have different numbers of the same VNTR.
C) PCR generates some sequences more than other sequences.
D) Restriction enzymes may not cut some VNTRs next to specific DNA sequences.
Answer: B
Section: 8.4
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.7

57) What is the function of Taq polymerase?


A) to denature DNA so its strands separate
B) to bond to complementary DNA
C) to free nucleotides from a DNA strand
D) to use primers to initiate DNA synthesis
Answer: D
Section: 8.4
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.7

58) Which item is used to produce genetic fingerprints of people?


A) RNA polymerase
B) Punnett squares
C) pedigree analysis
D) VNTRs
Answer: D
Section: 8.4
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.7

59) What are VNTRs?


A) fragments of DNA that have been denatured
B) nucleotide sequences that correspond to specific genes
C) distinct nucleotide sequences that everyone has in different numbers
D) nucleotide sequences that are different in different individuals
Answer: C
Section: 8.4
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.7

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60) For what purpose is the polymerase chain reaction (PCR) used?
A) to analyze a person's fingerprints
B) to separate fragments of DNA
C) to make many copies of a small amount of DNA
D) to cut DNA into many small pieces
Answer: C
Section: 8.4
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.7

61) Why is the polymerase chain reaction (PCR) so useful for DNA fingerprinting?
A) It can produce millions of copies from tiny amounts of DNA.
B) It can be used to compare DNA from different individuals.
C) It can identify the complete sequence of a gene.
D) It can allow scientists to visualize the DNA of specific individuals.
Answer: A
Section: 8.4
Skill: Comprehension/Application (Understand/Apply)
Learning Outcome: 8.7

62) What enzyme is used to synthesize daughter strands of DNA during PCR?
A) replicase
B) DNA polymerase
C) RNA polymerase
D) Taq polymerase
Answer: D
Section: 8.4
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.7

63) In DNA fingerprinting, amplified fragments of DNA are separated from one another by
which process?
A) filtering
B) chromatography
C) electrophoresis
D) PCR (polymerase chain reaction)
Answer: C
Section: 8.4
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.7

18
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64) On what basis does gel electrophoresis separate DNA segments?
A) weight
B) length
C) types of nucleotides
D) complexity
Answer: B
Section: 8.4
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.7

65) What does each different band on a DNA fingerprint represent?


A) gene
B) VNTR site
C) allele
D) pleiotropy
Answer: B
Section: 8.4
Skill: Knowledge/Comprehension (Remember/Understand)
Learning Outcome: 8.7

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