Professional Documents
Culture Documents
Module No:
M 16
Module Title
Pharmaceutical Science
Ruwan Raigamkoralage
[D.Pharm (Col). B.A.M.S (Col). MSc FST (SJP)]
Curriculum Outline –
Professional certificate in Care givers [Level -4]
Competency Profile: Competency area
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22-May-23
lecture series. [3hrs per day Aruna Pharmacy Matara Mr. Susantha
Matara Pharmacy Matara Mr. Krishanta
Hiruni Pharmacy Matara Mrs.Wathsala
& 2 days per week ] x 03
Suwaya Pharmacy Tangalle Mrs. Jayamali
weeks. Practical work sheet Aloka Pharmacy
Kodikara Pharmacy
Ambalathota
Middeniya
Mrs. Jayani
Mr. Sarath
My Care Pharmacy Beliatta Mrs. Suboda
will provide to record the Sethsuwa Pharmacy Angulukolapalassa Mr. Prasad
Sajeewa Pharmacy Walasmulla Mrs. Sajeewa
Jayarathna Pharmacy Embilipitiya Mr. Jayarathna
activities
Star Pharmacy Galle Mrs. Shasira
Medicare Pharmacy Galle Mrs. Pumi
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22-May-23
Drug administration
• Basic facts
Drug administration
Introduction
1) Systemic Routes
Enteral – Oral, Sublingual, Rectal
Par-enteral – Intra–Muscular[IM]
Intra–Venous[IV]
Sub–Cutaneous[SC] [Main 3 Parenteral routes]
2) Local Routes
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Drug administration
2) Local Routes
• Topical application (Local applications to surface of skin, mucus membrane
Drug administration
Oral Route
• The most common & convenient route of
drug administration to produce systemic effect.
But certain limitations such as;
a) unconscious patient
b) when the drug is inactivated by the gastric juice
c) Relatively slower on set of action
d) Irregular absorption-
e) When the drug is produce, excess gastric side effects
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Drug administration
• Sublingual Route
Drug administration
• Rectal Route
• The drug is administered through the rectum &
used either as local effect OR systemic effect.
This way is suitable for; a)Un-conscious patients.
b)Gastric irritable patients
Two main dosage forms for rectal administration; as Enema
[liquid rectal dosage form] & as suppositories [solid rectal dosage form].
Suppositories tend to soften at room Temperature.
So, need to be refrigerated.
Explain the procedure with providing privacy. Instruct to lie on left side.
Breath to relax sphincter.
Insert the suppository beyond the internal anal sphincter.
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Drug administration
• Intra venous Route
• Drug is directly injected in to the
veins.[Means directly to systemic
circulation.
• No steps of disintegration & dissolution
like in oral]
• The quickest method of drug
administration.
• [So prefer when emergency call for an
immediate response]
Drug administration
• Intra Muscular Route
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Drug administration
Subcutaneous Route
• Drug is injected under the skin for further slower action than I.M
Drug administration
Intramuscular
Subcutaneous
Intravenous
Intracutaneous
Epidermis
Corium
(cutis/dermis
Vein
Muscle
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Drug administration
• Time variability for start of action of different dosage forms
Drug administration
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• Daily application of surgical spirit may case roughening of skin & difficulty in
piercing. So it is not to be applied routinely to clean the skin.
The recommended method of cleaning the injection site
at home is with soap & water.
• Raise a skin fold up, especially important for pts who are thin.
• Insert the injection needle at 90 degree to the skin rather than at an angle
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Placebo effect
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What is
Placebo drug ?
• Placebo effect = Healing power of mind..?
Every patient has inner healing capacity means power of mind in healing.
Ex. Role of emotional peptides. [Over 300 already identified]
Ex – Endophines.
Any questions?
Thank you and Good luck
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1. Patient Factors
• Multiple morbidity-
multiple diseases needing treatment with several
medicines at same times.
So greatly increase risk of D.I, ADRs
• Poor Compliance
• Ploy Pharmacy – Eg: In very old people, features of normal ageing: like mild joint
pains, gravitational ankle swelling, difficulty in maintaining balance, light headache &
slightly reduce appetite are some times mistaken as disease & treated with medicines
unnecessarily. [ ? Pharmacist be aware – OTC]
Case study – Most elderly have bi lateral ankle oedema due to gravitational
factor. So relieved by exercise & elevation of legs.
But unnecessarily diuretic is given…..? If Elderly male >> having BPH >>
Urinay retention >> ???
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22-May-23
Warmest congratulations Flamingo Pharmacy Academy.. Wishing you even more success in the future.
Thank you
Presented By
Ruwan Raigamkoralage
D.Pharm (Col), MSc. FST (SJP)
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