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    Natural selection and genetic drift both influence allele frequencies over time, but natural selection is influenced by an allele's effect on fitness while genetic drift is influenced by random chance events. The bottleneck effect occurs when a small group founds a new population, reducing genetic variation, while the founder effect is when a new population is established from a few members of the original population, influencing allele frequencies. Genetic drift would have the least likelihood of fixing an allele in present-day India due to its large population size. When a lethal recessive allele reaches mutation-selection equilibrium with a dominant allele, its expected frequency can be calculated based on the mutation rate. In balancing selection, heterozygote advantage maintains genetic variation as the fitness benefit to heterozyg

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    Natural selection and genetic drift both influence allele frequencies over time, but natural selection is influenced by an allele's effect on fitness while genetic drift is influenced by random chance events. The bottleneck effect occurs when a small group founds a new population, reducing genetic variation, while the founder effect is when a new population is established from a few members of the original population, influencing allele frequencies. Genetic drift would have the least likelihood of fixing an allele in present-day India due to its large population size. When a lethal recessive allele reaches mutation-selection equilibrium with a dominant allele, its expected frequency can be calculated based on the mutation rate. In balancing selection, heterozygote advantage maintains genetic variation as the fitness benefit to heterozyg

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    6 views1 page

    QGenetics Tutorial 5

    Uploaded by

    wend23
    Natural selection and genetic drift both influence allele frequencies over time, but natural selection is influenced by an allele's effect on fitness while genetic drift is influenced by random chance events. The bottleneck effect occurs when a small group founds a new population, reducing genetic variation, while the founder effect is when a new population is established from a few members of the original population, influencing allele frequencies. Genetic drift would have the least likelihood of fixing an allele in present-day India due to its large population size. When a lethal recessive allele reaches mutation-selection equilibrium with a dominant allele, its expected frequency can be calculated based on the mutation rate. In balancing selection, heterozygote advantage maintains genetic variation as the fitness benefit to heterozyg

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    © All Rights Reserved
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    of 1

    1) What is the similarity and difference between the events of natural selection and

    genetic drift?

    2) Describe an example each demonstrating the bottleneck effect and the


    founder effect.

    3) In which of the following types of societies would genetic drift have the least
    likelihood of fixing the allele to 0 or 1?

    A. A group of 12 isolated humans living 80,000 years ago in New Zealand


    B. India at present time
    C. A local ethnic community of 50 members who have had no contact with
    outsiders in Sarawak for 10 generations
    D. New Zealand at present time

    4) A completely recessive allele k is lethal in homozygous condition. If the


    dominant allele K mutates to k at the rate of 5 x 10 -6 per generation, what is
    the expected frequency if the lethal allele when the population reaches
    mutation-selection equilibrium?
    5) In cases of heterozygote advantage in balancing selection, how do the
    opposing tendencies balance out each other to achieve a dynamic
    equilibrium?

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