Professional Documents
Culture Documents
1 Anatomy
1 Anatomy
19 - 12:20
Part I 1 Anatomy 2
I
| 01.03.19 - 12:20
1 Anatomy
Denita Ryan
Abstract
Knowledge of the anatomy of the nervous system is crucial for nurses caring
for patients with neurologic diseases or disorders because they must thor-
oughly understand the normal neuroanatomy to make meaningful correlations
between anatomical and clinical findings. The nervous system consists of the
central nervous system and the peripheral nervous system. This overview of
the normal neuroanatomy includes basic surface structure, the ventricular sys-
tem, and the vasculature of both the brain and the spine.
2
| 01.03.19 - 12:20
Anatomy
Neurons
● Fundamental building blocks
● Highly specialized
● Conduct and receive nerve impulses, as well as release chemical
transmitters
○ Soma: Cell body of the neuron
3
| 01.03.19 - 12:20
● Synapse
○ The junction between neurons, in which impulses are transmitted
● Neurotransmitters
○ Chemical substances that promote, inhibit, or alter cellular response
○ Over 100 neurotransmitters have been identified, including
4
| 01.03.19 - 12:20
Anatomy
Neuroglial Cells
● Specialized support cells. They include
○ Astrocytes: Supply nutrients to the brain
○ Ependymal cells: Line the ventricles and help produce cerebrospinal fluid
(CSF)
○ Oligodendrocytes: Form protective myelin sheath around the axons
○ Schwann’s cells: Form the myelin sheath around the peripheral nerves
1.2.1 Scalp
The scalp consists of several layers that cover the skull.
● Skin (dermal) layer
○ Protects the skull
○ Contains hair
● Subcutaneous layer
○ Vascular; may bleed profusely
● Galea
goose egg
● Periosteum
○ Thin layer of connective tissue that covers the skull
1.2.2 Skull
The skull (▶ Fig. 1.3) is composed of eight fused bone plates.
5
| 01.03.19 - 12:20
Cranial Bones (n = 8)
● Frontal
● Temporal (n = 2); thinnest portion of bone
● Parietal (n = 2)
● Occipital
● Sphenoid
● Ethmoid
6
| 01.03.19 - 12:20
Anatomy
1.2.3 Brain
The brain (Box 1.3 Just the Facts: The Brain), largely recognized as the most
complex organ in the human body, has a complicated anatomy. Sulci (singular,
sulcus) are small separations between brain tissue. Gyri (singular, gyrus) are
folds (i.e., wrinkles) on the surface of the brain. The purpose of the sulci and
gyri is to increase the surface area of the brain.
Fissures are deep separations between the cerebral hemispheres (or lobes)
of the brain, commonly used as geographical markers. The best-known fissures
are as follows:
● Great longitudinal fissure
Meninges
The meninges (▶ Fig. 1.4) are the three layers of thick connective tissue that
cover the entire brain and spinal cord.
● Pia mater
○ Tough, fibrous layer between the arachnoid mater and the skull bone
7
| 01.03.19 - 12:20
○ Spaces above (epidural) and below (subdural) the dura are typical locations
for dural hematomas, a common type of brain injury (Box 1.5 Clinical
Correlation: Dural Hematomas)
– The tentorium, a tent-like fold of dura that separates the cerebrum and
cerebellum, serves as an important anatomical marker
8
| 01.03.19 - 12:20
Anatomy
Ventricular System
The ventricular system produces and circulates CSF (Box 1.6 Cerebrospinal
Fluid). It includes four cavities (i.e., ventricles) that contain CSF and the trans-
port system that circulates CSF throughout the brain and spinal cord (Box 1.7
Clinical Correlation: Disorders of the Ventricular System). The components of
the ventricular system are
● Ventricles
○ Situated in the center of the brain
○ The four ventricles include the right and left lateral ventricles, the third
ventricle, and the fourth ventricle (▶ Fig. 1.5. and ▶ Fig. 1.6)
○ Communicate with other ventricles
○ Composed of ependymal cells
● Choroid plexus
9
| 01.03.19 - 12:20
● Arachnoid villi
○ Reabsorb CSF into blood
○ Transport CSF to dural sinus
10
| 01.03.19 - 12:20
Anatomy
Cerebrum
The cerebrum consists of two cerebral hemispheres, right and left.
● Separated by the great longitudinal fissure
● Surface of the brain is covered by gray matter, which is composed of millions
of neurons
Supratentorial Region
The supratentorial area of the brain consists of the frontal, parietal, temporal,
and occipital lobes (▶ Fig. 1.7) and the corpus callosum.
● The frontal lobe controls
○ Emotions and behavior
○ Attention
○ Motivation
○ Judgment
○ Broca’s area: Motor aspect of speech (i.e., expressive speech)
○ Initiation of motor integration
11
| 01.03.19 - 12:20
○ Problem-solving
○ Bowel and bladder function
● The parietal lobe controls
○ Interpretation of characteristics of sensory input (e.g., pain, temperature,
and touch)
○ Processing of visual–spatial information (nondominant hemisphere)
○ Praxis (dominant hemisphere)
○ Memory
○ Musical awareness
○ Sequencing
● The occipital lobe controls
○ Visual perception
○ Interpretation of the written word
● The corpus callosum is a thick band of nerve fibers running longitudinally
that connects the hemispheres
12
| 01.03.19 - 12:20
Anatomy
Diencephalon
Located in the posterior portion of the forebrain, the diencephalon (▶ Fig. 1.8)
contains several important structures, primarily the thalamus and the hypo-
thalamus that form the floor of the third ventricle.
Thalamus
● Sensory relay system
● Integrative center that connects various areas of the brain
● Pain awareness
Hypothalamus
● Deep structure forming the wall of the third ventricle
13
| 01.03.19 - 12:20
Internal Capsule
The internal capsule is a large bundle of nerve fibers, both motor and sensory,
that connect the various areas of the brain and spinal cord.
● Composed of white matter
● Anatomically critical; controls major motor and sensory functions
14
| 01.03.19 - 12:20
Anatomy
● Caudate nucleus
● Amygdala
Infratentorial Region
Brainstem
The brainstem is a very small area of the brain that contains extremely
eloquent brain tissue. The brainstem is composed of
● Midbrain
○ Origin of oculomotor and trochlear nerves (cranial nerve [CN] III and CN IV)
● Pons
○ Origin of trigeminal, abducens, facial, and vestibulocochlear nerves (CNs
V-VIII)
○ Located between the midbrain and medulla
15
| 01.03.19 - 12:20
● Medulla
○ Located below the pons and above the spinal cord
○ Origin of CN glossopharyngeal, vagus, spinal accessory, and hypoglossal
regulate
– Heart rate
– Blood pressure
– Respiration
Cerebellum
The cerebellum, located in the posterior fossa and attached to the brainstem,
influences the following:
Limbic System
● Complex system that includes
○ Hypothalamus
○ Hippocampus
○ Amygdala
16
| 01.03.19 - 12:20
Anatomy
17
| 01.03.19 - 12:20
Anterior Circulation
The anterior circulation supplies the cerebrum anterior to the posterior edge of
the temporal lobe (▶ Fig. 1.11). It includes arteries originating from the carotid
arteries.
● Internal carotid arteries
● Middle cerebral arteries
Posterior Circulation
The posterior arterial circulation supplies the inferior portion of the temporal
lobe, the brainstem, the cerebellum, and the spinal cord (Box 1.11 Clinical Cor-
relation: Disorders of the Cerebrovascular System). It consists of arteries arising
from the subclavian artery.
● Vertebral arteries
● Basilar artery
● Posterior cerebral arteries
18
| 01.03.19 - 12:20
Anatomy
Venous System
○ Collects blood from the inferior surface of the brain, including orbits
● Superior sagittal sinus
○ Collects blood from the cortical veins on the convexity of the brain
○ Drains CSF
● Bridging veins
○ Connect the brain and the dural sinuses
1.2.4 Spine
● Consists of multiple bony structures called vertebrae (▶ Fig. 1.12)
● Vertebrae are stacked on top of each other, providing support for the head
and the body
● The 33 vertebrae make up the 5 areas of the spine
○ Cervical (n = 7)
○ Thoracic (n = 12)
○ Lumbar (n = 5)
○ Sacrum (n = 5, fused into 1 segment)
19
| 01.03.19 - 12:20
20
| 01.03.19 - 12:20
Anatomy
Arch
● Posterior portion of the vertebra
● Each arch consists of
○ Pedicles
○ Lamina
Articulation
● Vertical alignment of the vertebral bodies, with the disk in between and the
facets on either side
Cervical Vertebrae
Thoracic Vertebrae
● Trunk-level vertebrae (n = 12) (▶ Fig. 1.14)
● Slender part of the spinal cord
Lumbar Vertebrae
● Low-back vertebrae (n = 5) (▶ Fig. 1.15)
● Largest vertebrae
● End at conus medullaris (i.e., the cone-shaped end of the spinal cord)
○ Ligamenta flava
21
| 01.03.19 - 12:20
Meninges
● Membranes that cover the spinal cord and the brain
Intervertebral Disks
● Cartilaginous cushions between vertebrae; center of disk is nucleus pulposus
(Box 1.12 Clinical Correlation: Herniated Disk)
● Differ in size and shape, depending on the size of vertebrae
● Serve to cushion and absorb movement and stress
22
| 01.03.19 - 12:20
Anatomy
23
| 01.03.19 - 12:20
Spinal Cord
● Elongated mass of nerve tissue
● Extends from C1 to L1 or L2 in adults
● Terminates at the conus medullaris, around L1
● Serves as the primary pathway between the peripheral (nonvisceral) areas of
the body and the brain
● Segmented by region and groups of nerves, and numbered by level of
vertebral column
● Covered by meninges and cushioned by CSF, which fills the central canal of
the spinal cord and the space between the spinal cord and the meninges
● A cross-section of the spinal cord reveals a butterfly- or H-shaped central
area of gray matter (dorsal and ventral horns) surrounded by white matter
(myelinated axons)
Spinal Nerves
● Part of the PNS; see also section on PNS in this chapter
● Exit the spinal cord in bilateral pairs
Sensory Pathways
● Afferent (i.e., ascending) pathways carry sensory information from specific
areas of the body (i.e., dermatomes) to the sensory cortex in the brain
● These sensations travel along one of the two major pathways
○ The dorsal column: Pain and temperature sensations travel via the dorsal
column to the medulla, where they cross to the opposite side and enter the
thalamus (▶ Fig. 1.16)
○ The ganglia: Touch, pressure, and vibration sensations travel via the ganglia to
the medulla, where they cross to the opposite side and enter the thalamus
● The thalamus is the relay station that transmits all impulses to the sensory
cortex for interpretation
Motor Pathways
● Ventral, efferent, and descending motor pathways transmit motor impulses
from the brain to specific muscles
● These pathways originate in the motor cortex of the frontal lobe of the brain
● Voluntary motor activity is regulated by the interaction between the
pyramidal and extrapyramidal systems
○ Pyramidal: Responsible for fine motor movement (▶ Fig. 1.17)
○ Extrapyramidal: Responsible for gross motor movement
● Motor impulses cross at the medulla to the opposite side and progress along
descending pathways, affecting contralateral motor function
24
| 01.03.19 - 12:20
Anatomy
nerve roots
● The artery of Adamkiewicz, which originates from the aorta, supplies about
Venous System
● Intradural system: Consistent with arterial pathways
● Extradural system: Empties into the vena cava
25
| 01.03.19 - 12:20
○ Thoracic (n = 12)
○ Lumbar (n = 5)
○ Sacral (n = 5)
○ Coccygeal (n = 1)
● Transmit sensory stimuli from receptors in skin, muscles, viscera, and
sensory organs to the dorsal column of the spinal cord
26
| 01.03.19 - 12:20
Anatomy
Cauda Equina
● Means “horse’s tail” in Latin
● Collective term for nerve root cluster at inferior edge of spinal cord
27
| 01.03.19 - 12:20
28
| 01.03.19 - 12:20
Anatomy
Video
Video 1.1 The brain and spinal cord.
Suggested Readings
[1] Goldberg S, Ouellette H. Clinical Anatomy Made Ridiculously Simple. Miami, FL: MedMaster;
2016
[2] Grigaitis M. Nursing assessment of patients with neurological disorders. In: Osborn KS, Wraa CE,
Watson A, eds. Medical Surgical Nursing: Preparation for Practice. 2nd ed. Boston, MA: Pearson; 2013
[3] Hansen JT. Netter’s Clinical Anatomy. 3rd ed. Philadelphia, PA: Elsevier Saunders; 2014
[4] Hickey J. Clinical Practice of Neurological and Neurosurgical Nursing. 7th ed. Philadelphia, PA:
Wolters Kluwer Health; 2013
[5] Iannotti JP, Parker R. The Netter Collection of Medical Illustrations: Musculoskeletal System,
Volume 6, Part II—Spine and Lower Limb. 2nd ed. Philadelphia, PA: Elsevier Saunders; 2013
[6] McIlwain H, Bachelard HS. Biochemistry and the Central Nervous System. 5th ed. Edinburgh:
Churchill Livingstone; 1985
[7] Netter FH. The CIBA Collection of Medical Illustrations. Summit, NJ: CIBA-Geigy Corp.; 1991
[8] Wilson-Pauwels L, Akesson EJ, Stewart PA, Spacey SD. Cranial Nerves in Health and Disease. 3rd
ed. Shelton, CT: People's Medical Publishing House—USA; 2010
[9] Inner Body. http://www.innerbody.com. Accessed June 9, 2017
[10] University of British Columbia. Anatomy of the brain. http://www.neuroanatomy.ca. Accessed
June 9, 2017
29