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Pro11011 iurO le vo

Nomo biem 7n-110m/d4


giacte ovo
(aRin) eral
8lurare 100d 10-4DMgId4
do 70 140mgl44

mpoN OuUYre of Blood gucop tevel


Detny
qluconeogeeris> tythenr of giurase Atom
Oe non cmtonyhute prerura

this nctud0*lactato
Gty@ro
mainly in 4 *pNopianly toA
Chutoreogenet! iNerSKidney AA
Glutegenclysis> breaKdou Gf 9tygon into
ghurase
Otilizoto0 of Blood gucare jeve!

QItolysi s,1CA
HMP
qlyCogenens
lipogene tis
Pminotugoi ptc
Oautoe levMel:
whon bl ood gtucoso
over is to) whenblo0d gluoje lev
move thon movMo
Bhit tond iuon oned
THIypO9tyremia ()
hpogtyremia
G1utogon
blesod glut0ue lovel 2Epinephrine
3-Thyyoxin
nrveates h 4:GH
Uptaxe of utoso 5 ACTH
by the cer
-torto
Via
10uin dependent uronpo90
TYOnipoYtpr Glurnge
TGu-4]
upta Ke GLUT4
ENsuip yolysp
^HMP stunt
JAluconebg0neris
lyLAgenolysis
Mechaniem Tegulat
state.
Dphosphorylated
Alytogen etobolitm
metnkolism tve

vou GIHog0n synthase- 10


naym GlytogéneJ
ytogen phasphovyla1o)
MtOgenolyns
10suin B4L Phaphonl@ed tale
Gutog on BGL
pothuy

q luragon in lver e, Glutmgon <p Pine phiine n


1Usele

qtucago H ovoud iuto fomalioOn.

Adonyl (ycla se
> CAMP, iuogeyntb
AMP
pug tophaggs Glucose
nortive
PK PKo
91yrogen
Cinortiv (attive) uOI
Pol Khane &ynthase

Phos PhoylaJe Actve phophrtare


knate
Kinase
(inative)

Gyroge) Glytoge
Phosphoyyle
Eimto Sbmrai
Glueose
um: ppE)
Phagphiliasteraya

10Uhn utilizer the CAMP


ovoYS pue to the Utlizata
Of CAmp
vliau

Pk Glytogen
inattwe yodbate CD

t qttvote
the
SnAlinIl iDhl
nltn hb GJutonet
Gjuton
.Glutoneo geness
Gluagon-
timnat NUONene
qjutoneop
4 Key erzym
ymivat0 Cmbotglayo

Puruva (ovborykinaro
-phatphoenol
bispholphotase
tr6-
9 YUtof
4. GluIONO 6-PhoJphole

nduttion pvateovkalyh
INuin
SReprosuron
Glungon
ATCtylo a ahvatoY fyrngt
Cvbodyttp
Ciuatt a aCt Vgtor of f-h6 Bi
Phote

3 qlolyftS w d e

qluokinae / HeLokinaNO
Phatpho-vutokinase
Pyruatgknae unulateqnsulid
8paute of
gfurose
uhlizoton

tatus of gurgle in vanous tate

OteY mea
Glutote ytogon syntnes
SourtoeeneYgy>
OY bratn qluase
post absoYpbve stute
In b/w mtal) hver gly
9ly tognalyr/
togenalyIA
B1a-glUcogO
AteY 14-18hu GuoneaeaMJLLN
of stovatidm
BTainKOtana landr
Boym- kelone adin
of
HaYvation

Gutoe 0due p0Ydap


mothd
EStmauon by GoD-poD Meth
by
blotd
glult
HYPeslytemi a
HyReY olyCemia TMuhathetay
0 DM intake

OHypetbyroidm
HyPoatbivit
HypenPrtuitOnsm Gf thisglond
H y peradenalitm
thot s pituitary
AHena
hyoid
OCn
TT7

Psonganey olialete
Regutabin f Btod glutak leve
NoVmal blood Ho-11Omg/d
. gluctre jevej
FOstin) Rena
Pott 9luase Load > 110-140mg/dd thvelhd4
Rondonn Fo-40 mgld
NON lama glurase 1evel 4lyrosurio

1Mpaiant JOLATCe Of Blood gluro0 tevel


Dietary
synthesr of glucase
fom
qluconecg enesrig>
ORR non corbonyehrte prerura

this inctud! * tactate

mainly in K *Piopionly CoA


iver Kidney AA
Ghuatooktgene tto
Y0genoly > breMKdouN 0f glyogon
9lucre
otilizaton of Blood ucofe jevel
q1tolusis, 1CA
HMp
*QlyCogenenis
* lipogenesis
Aminosug01 ete

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