The document discusses the relationship between diabetes and obesity among the Pima Indians, noting that while the American Pima have high rates of obesity and diabetes, their Mexican cousins who maintain a traditional lifestyle do not suffer from these problems to the same extent, presenting an interesting case study. Technological and lifestyle changes that occurred over the 20th century dramatically altered the way of life for the American Pima but not as much for the isolated rural Mexican Pima, demonstrating how genetic predisposition can be expressed differently depending on environmental factors like diet and activity levels. The discussion considers theories around "thrifty genes" and how human biology may
The document discusses the relationship between diabetes and obesity among the Pima Indians, noting that while the American Pima have high rates of obesity and diabetes, their Mexican cousins who maintain a traditional lifestyle do not suffer from these problems to the same extent, presenting an interesting case study. Technological and lifestyle changes that occurred over the 20th century dramatically altered the way of life for the American Pima but not as much for the isolated rural Mexican Pima, demonstrating how genetic predisposition can be expressed differently depending on environmental factors like diet and activity levels. The discussion considers theories around "thrifty genes" and how human biology may
The document discusses the relationship between diabetes and obesity among the Pima Indians, noting that while the American Pima have high rates of obesity and diabetes, their Mexican cousins who maintain a traditional lifestyle do not suffer from these problems to the same extent, presenting an interesting case study. Technological and lifestyle changes that occurred over the 20th century dramatically altered the way of life for the American Pima but not as much for the isolated rural Mexican Pima, demonstrating how genetic predisposition can be expressed differently depending on environmental factors like diet and activity levels. The discussion considers theories around "thrifty genes" and how human biology may
numbered section. technological delating 1 'There are fewer wheelbarrows waiting to be invented.' This contention appears to the practical use in in a millennial essay on ‘The road to riches', which was seeking to develop an industry of scientific explanation for the astonishing rise in living standards in the West over the past knowledge couple of centuries. innovation Ithe 2 Why did The Economist's anonymous writers choose the wheelbarrow as their introduction of new exemplar of progress? Because it had transformed construction. things, ideas or ways of 3 The pyramids of Egypt are built without them; nineteenth-century skyscrapers doing something could not have been. 4 A corollary of this argument will be that the pace of technological innovation is previously! happening bound to slow down, instead of, as was previously assumed, endlessly increasing. or existing before the 5 Scientific discoveries are likely to continue indefinitely, subject to funding. If blue- event or object that you sky research is curtailed in one area, for example genetics in the United States, it are talking about is going to be certain to migrate to another. assumelto think or 6 Technology, on the other hand, encounters, or is about to encounter, a ceiling, accept that something is according to this argument. true but without having 7 The practical, tangible innovations that have lifted much of humanity from proof of it poverty to affluence, from subsistence agriculture through the Industrial research ithe careful Revolution to, in many countries, service-based economies - these innovations study of a subject, were already invented. especially in order to 8 There will be no more significant, radical new inventions that transform an discover new facts or industry. Instead, gradual and incremental improvements would be the path of information about it the future. technologyiscientific 9 The counter-arguments to this are twofold. Firstly, it can be argued that we were knowledge used in not capable of knowing what has not yet been invented. practical ways in 10 Before the wheelbarrow exists, no one felt the need for one. There may be plenty industry, for example in more such devices waiting in the wings. There is no shortage of intelligent, designing new machines ingenious people eager to make their mark as inventors. 11 The second argument is pointing to entirely new areas of human activity, for encounterito example in personalized medicine and in human-machine interaction. discover or experience 12 The future may see scientists inventing things we cannot yet imagine. Instead of something, especially wheelbarrows - sturdy objects that anyone can use and understand - our future something new, inventors may have been working at a microscopic, or indeed molecular, level. unusual, or unexpected capableihavingthe ability or qualities necessary for doing something devicelan object or a piece of equipment that has been designed to do a particular job interaction!a process or situation in which two things communicate with or have an effect on each other
014 01 Challenge yourself
F Complete the text with the correct form of the verb in brackets. The inter-relationship between diabetes and obesity 1___________ (be) for some time a matter of interest to researchers and clinicians. The case of the Pima Indians is one that continues 2___________ (be) much studied. They are a group of Native Americans w ho 3___________ (live) for thousands of years in what is now the southwestern United States and northern Mexico. Their traditional economy was based for the most part on subsistence agriculture, and they 4___________ (endure) periods of famine as well as plenty. In the twentieth century, the way of life 5___________ (change) dramatically in the former country, but not so much in the isolated rural areas of the latter. By 2000, the American Pim a 6___________ (become) obese, a n d 7___________ (develop) one of the highest rates of diabetes in the world. However, their Mexican cousins do not suffer these problems to nearly the same extent.
G Circle the correct option.
The situation is as close to a scientific experiment as it Hs/ will be possible to find intervention Ithe act in the field, that is, without direct and deliberate intervention. The American and or process of becoming the Mexican Pima 2share/are sharing essentially the same genotype, and until a involved in a situation few generations ago they also 5shared/were sharing the same phenotype. In other in order to improve or words, although they 4have/ would have very similar genetic make-up, the two help it groups, which once had the same body shape, now swill look/look different and similar :like somebody/ 6will suffer/suffer different health problems. This genotype-phenotype distinction something but not is a fundamental one for any study of genetics. exactly the same Neel (1962) proposed that the predisposition towards diabetes 7will be caused/ distinctions clear is caused by what he called a ‘thrifty gene', one that &has enabled/enables the difference or contrast body to store fat when food is plentiful, in preparation for the famine that 9will especially between lie/lies around the corner. This theory has undergone modification in the past people or things that are half-century. Barker's hypothesis (1997) posits a 'thrifty phenotype': if a pregnant similar or related woman is starved of nutrients, her baby l0is/will be born small, and is likely to fundamentallserious develop certain diseases later in life. The growing foetus is prepared for a life in and very important which famine uis/is going to be likely. In reality, of course, famine 12has been/is increasingly unlikely for most citizens in most countries today. We suffer from the undergolto experience opposite problem, overnutrition. Our biology, which 15had evolved/evolves in slow something, especially a tiny steps, has not kept pace with the rapid changes in the way we live, and one change consequence 14had been/is the epidemic of diseases of affluence, notably obesity modification ithe act and diabetes. or process of changing something in order to H Write 100-200 words about the past, present, and future of the place you come improve it or make it from (village, city, or country). more acceptable evolvelto develop gradually, especially from a simple to a more complicated form