Anti - NMDA Receptor Encephalitis

Anti -
NMDA R
Encephalitis is an autoimmune disease ,
where

the creates antibodies brain

body against NMDA
Receptor in .

Anti : Autoimmune Response

NMDA
Receptor : N -

methyl -
D-

Aspartate Receptor
( Glutamate Receptor )

Encephalitis Causing swelling

: &

brain
Disruption in
signaling .

• More common in Homen .

primarily affects the
young ,
including
children and adults
young
.
 associated with this disease
• Some
patients also have a tumor ,

the most common

type is Ovarian teratoma in women .

Signs & Symptoms

Patients start with less
symptoms and then
progress
•
severe ,

requiring hospitalization
to a condition .

Behavior ( Paranoia hallucinations etc )

( is , ,
aggression
in
Cognition Wii , Seizures
Iii ,
Memory Deficit
cuiii ) Autonomic Dysfunction
speech Disorder
.

(in

in loss of Consciousness

Movement Disorder ( motions

evil
Rhythmic with arms or
legs ,
or

abnormal motion of face / mouth )

 Diagnosis
Clinical
symptoms
•

Confirmed via lab

Testing of CSF Blood serum
•

or
 No Known Cause for
Treatmen t
*

anti -

NMDA R
Encephalitis .

First line of Treatment :

d) Tumor Removal ( if any )

( is steroids
iiiii Plasma Exchange ( Plasm apheresis )
(in Intravenous immunoglobulin (1×19)

Second line of Treatment :

( is Cell Cept ( Immunosuppressant )

in Rituximab ( Controls inflammation )
iii ,
Cytoxan ( for cancer )
c
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