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random specimen
1.Which of the following is the urine specimen of
choice for cytology studies?
6. A 35-year old diabetic woman is suspected of
a. first morning specimen
developing renal insufficiency. Which of the
b. random specimen following specimens should be obtained to
determine the amount of creatinine being excreted
c. midstream "clean catch" collection in the urine?
d. timed collection a. 2-hour postprandial
3. Substances that show diurnal variation in their b. decrease in pH and specific gravity
urinary excretion pattern are best evaluated using a: c. decrease in glucose and ketones
a. first morning specimen d. decrease in bacteria and nitrite
b. midstream "clean catch" specimen
a. acid addition
A. 2 hour postprandial
17. substances bound to plasma proteins in the
B. 12 hour timed collection blood can be eliminated in the urine by
C. Tubular secretion
D. Dysuria
22. the best test to measure the level of renal
function and determine the stage/s of renal disease
A. Tubular secretion rate 27. An ideal urine preservative should show the
following, except
B. Tubular reabsorption tests
A. Inhibits urease
C. Renal blood flow tests
B. Bactericidal
D. Glomerular filtration rate
C. Can preserve formed elements
D. Interferes with chemical tests
A. 2- hour postprandial
A. Non invasive
B. Prostatic fluid
C. Seminal fluid
3. Approximately what percentage of blood does the 13. Passive reabsorption of water takes place
kidney receive from the heart? throughout the nephron except:
A. 15% A. Proximal convoluted tubules
B. 25% B. Ascending loop of henle
C. 45% C. Descending loop of henle
D. 50% D. Distal convoluted tubule
4. Albumin is important for oncostatic pressure. It is 14. Active transport of chloride in the ascending
maintained in the capillary because of: loop is accompanied by:
A. Large molecular size A. Passive reabsorption urea
B. Presence of H++ B. Active reabsorption of amino acids
C. Negative charge of barrier C. Passive reabsorption of sodium
D. Positive charge of the PCT D. Active reabsorption of water
5-10 Tubular reabsorption: indicate where the 15. A 45 year old male with a history of high blood
substance is transported by active or passive pressure is seen at the ER. Workup showed glucose
transport damage. What is the possible cause of the glucose
in the urine?
A. Active transport
A. Acute tubular damage secondary to
B. Passive Transport
myocardial infarction.
C. Both
B. Diabetic nephropathy secondary to diabetes
mellitus
B. Aldosterone A. Tyrosine
D. Erythropoietin C. Bilirubin
D. Creatinine
A. Concentrated urine
D. Diluted urine
a. diabetes insipidus
b. radiographic contrast media
TOPIC 4: CHEMICAL TESTING B. turbid appearance
1. The normal straw color of urine is largely due to
C. characteristic odors
the presence of
D. presence of amino acids
A. urochrome
B. bilirubin
6. The presence of smoky urine is most likely
C. uroerythrin
indicative of
D. biliverdin
A. hemoglobinuria
B. hematuria
2. Emptying the bladder or urine voiding is otherwise
C. hemosiderinuria
known as
D. hemophilia
A. deglutition
B. diuresis
7. One of the following is characterized by a turbid
C. micturition
urine due to leakage of lymph:
D. renal incontinence
A. pyuria
B. chyluria
3. Which set of parts involved in urine formation is
C. bacteriuria
correctly sequenced?
D. cylindruria
A. glomerulus, proximal convoluted tubule,
loop of Henle, renal pelvis, collecting
ducts, ureter, urinary bladder, urethra 8. Brick dust refers to which of the following
crystals?
B. glomerulus, proximal convoluted tubule,
renal pelvis, loop of Henle, collecting A. amorphous phosphates
ducts, ureter, urinary bladder, urethra B. uric acid
C. glomerulus, proximal convoluted tubule, C. amorphous urates
loop of Henle, collecting ducts, renal
D. calcium oxalate
pelvis, ureter, urinary bladder, urethra
C. sediment assessment
10. The clearing of turbidity due to the addition of a
D. chemical testing dilute acid confirms the presence of
A. amorphous urates
5. Amino acid disorders are characterized by the B. amorphous phosphates
passage of urine with
C. bacteria
A. distinct colors
D. leukocytes and pus cells
16. The presence of many mucus threads in the
urine indicates
11. The presence of casts in the urine is called
A. renal inflammatory episode
A. chyluria
B. slightly dysfunctional bladder
B. casturia
C. normal kidney function
C. cylindruria
D. urine processing artifact
D. crystalluria
B. dipstick
13. Any transient increase in urinary volume is C. chemstrip
termed
D. multistix
A. diuresis
B. hypersthenuria
19. Regarded as the routine or basic urinalysis is the
C. polyuria
A. wet urinalysis
D. urolithiasis
B. special cytologic urinalysis
A. yellow
A. specific gravity
B. urinary volume 21. In the event that only one urine specimen is
obtained, which correct sequence shouldbe
C. clarity (appearance)
followed in wet urinalysis?
D. urine osmolality
1. bacteriologic examination
D. urobilinuria
A. 1-2-3-4
B. amorphous phosphates
22. The patient’s degree of hydration and urine
concentration can be estimated by examining D. bacteria
A. urine clarity
C. urine color 28. The dye Oil Red O is used to demonstrate the
presence of
B. urine odor
A. hematuria
D. urine crystals
C. lipiduria
B. chyluria
23. Small cloudy patches in normal urine due to the
presence of mucus is called D. pyuria
A. nebula
C. polydipsia
24. Which pigment causes the production of yellow
foam ? B. nocturia
C. bilirubin
26. Homogentisic acid forms brown-black urine 31. A urine sample with a specific gravity of 1.010 is
upon long standing -- a condition known as described as
A. porphyria
A. hyposthenuric D. 7.4
B. normosthenuric
C. glucose
A. lower urinary pH
33. Sound wave frequency and falling drop method C. increase urinary pH
are performed to assess the urine
B. produce neutral pH
A. osmolality
D. not affect urine pH
C. specific gravity
B. acidity or alkalinity
39. The ill effects of salicylic acid poisoning would
D. water content be aggravated by which of the following:A. diet rich
in meat
B. urine volume and color 40. In the tubular cells, the passing filtrate acquire
hydrogen ions in exchange for
D. urine pH
A. ammonium ions
C. sodium ions
35. The presence of high amounts of indican will
give a urine sample a B. bicarbonate ions
C. brown-black color
C. Diastix – 2
36. The average adult on a normal diet produces a
24-hour urine with a pH of about B. Uristix -2
A. 5.0 D. Chemstrip G – 1
C. 7.0
D. Functional proteinuria
43. The titratable acidity of a 24-hour urine collected
in ice utilizes as titrant the
A. 0.1N NaHCO3 48. A hazy urine with high protein content collected
after a heavy exercise is an example of
C. 0.1N NaCl
A. Intermittent proteinuria
B. 0.1N NaOH
C. Postural proteinuria
D. 0.1N NaNO3
B. Persistent proteinuria
D. Functional proteinuria
44. Bacterial growth in urine specimen is
characterized by all of the following except
A. clouding that cannot be cleared by 49. To detect the kinds of protein in the urine, what
acidification is needed is
B. Tamm-Horsfall glycoprotein
D. Immunoglobulin light chains 52. Tubular pattern proteinuria is seen in all of the
following conditions except
A. Fanconi’s syndrome
C. Wilson’s disease B. Both albumin and globulins can be
precipitated using SSA and TCA.
B. Pyelonephritis
C. Reagent strips can be used in assessing
D. Nephrotic syndrome
the degree of proteinuria.
A. 100 mg/dL
55. Also referred to as orthostatic proteinuria is
C. 130 mg/dL
A. postural proteinuria
B. 157 mg/dL
C. Bence Jones proteinuria
D. 220 mg/dL
B. intermittent proteinuria
D. functional proteinuria
61. Urine glucose testing serves to check endocrine
function to diagnose the disease
56. Which substance may affect urinary pH testing?
A. Diabetes insipidus
A. protein
C. Diabetes mellitus
C. glucose
B. Hyperglycemia
B. ketone bodies
D. Glucosuria
D. bilirubin
D. Chemstrip G
69. In galactokinase deficiency, galactose cannot be
converted to glucose. From what sugar was the
64. What enzyme will oxidize glucose into gluconic galactose that appears in the urine derived?
acid and hydrogen peroxide?
A. sucrose
A. hexokinase
C. lactose
C. glucokinase
B. maltose
B. glucose oxidase
D. starch
D. glucose peroxidase
A. Clinistix C. CuSO4
C. Multistix B. Cu2O
B. Chemstrip-G D. CuO
D. Clinitest
72. What method is best to measure the individual
reducing sugars in urine?
67. All of the following are reducing sugars except
A. Copper reduction method
A. glucose
C. Thin layer chromatography
C. galactose
B. Clinitest
B. fructose
D. Clinistix
D. sucrose
C. bile pigments
B. ketone bodies 79. The main ingredient of the Gerhardt’s test for
the detection of urine diacetic acid is
D. porphyrins
A. nitroprusside
C. ferric chloride
74. The most abundant among these organic
substances in the urine is B. nitroferricyanide
C. diacetic acid
C. hydrogen peroxide
75. The most abundant among these inorganic urine
constituents is B. glutathione
C. bicarbonate
C. excessive exercise
B. type I diabetes mellitus 82. The Multistix reagent pad for blood uses of the
chromogen tetramethylbenzidine which,
D. carbohydrate-rich diet
in the presence of blood, causes a color change
from
77. Sodium nitroferricyanide reaction (Acetest) is
A. yellow to red
specific for urinary
C. yellow to orange
A. urobilinogen
B. yellow to green
C. bilirubin
D. yellow to purple
B. diacetate
D. sucrose
83. What red-brown pigment in the urine is produced
after rhabdomyolysis
78. Rothera’s wet method can detect all of the
A. hemoglobin
following except
B. B. myoglobin
A. acetoacetic acid
C. intact RBCs
C. acetone
D. hemosiderin A. Hecht’s test
C. Hoesch’s test
C. hemosiderin
90 & 91. A positive nitrite test indicates A. (90) C.
B. amino acids while a positive leukocyte esterase
A. bacteriuria
B. bilirubin
92. C-Stix reagent strips are impregnated with
D. myoglobin buffered phosphomolybdate to detect
A. ascorbic acid
B. nitrite
93. The 5-hydroxyindole acetic acid (5-HIAA) is a
D. leukocyte esterase byproduct of metabolism of
A. porphyrins
amino acid?
D. porphobilinogen
95. Defects in the synthesis of heme moiety of
hemoglobin would cause
B. in vitro hemolysis
D. hemorrhagic fever
A. Microscope
C. Wood’s lamp
B. TS meter
D. UV light
A. hexokinase
C. heme
B. myoglobin
D. hydrogen peroxide
A. acetone
C. acetoacetic acid
B. beta-hydroxybutyric acid
D. urea
A. diabetes mellitus
C. diabetes insipidus
B. nephrotic syndrome
A. Urobilinogen
C. Nitrite
B. Ascorbic acid
D. Granular Casts
D. Chronic glomerulonephritis
2. The presence of renal tubular epithelial cells and
E. NOTA
casts is an indication of
B. Chronic glomerulonephritis
3. Differentiation between cystitis and
Pyelonephritis is aided by the presence of C. Nephrotic Syndrome
C. Bacteria
4. The presence of WBCs and WBC casts with no A. Presence of WBC casts in LPF
bacteria is an indicative of
B. Presence of budding yeast
A. Chronic pyelonephritis
C. Presence of numerous leukocyte and
B. Acute tubular necrosis bacteria
E. NOTA
9. The presence of this type of urinary casts is an
indication of an extreme urine stasis.
5. This type of cast if form the by products of
protein metabolism which appears colorless to A. Waxy casts
shades of yellow easily viewed with bright field
B. Fine granular cast
microscopy
C. Mixed Cellular cast
A. Waxy casts
D. Hyaline cast
B. Bacterial Cast
E. Both B and C are correct
C. WBC casts
of symptoms consistent with damage to the
glomerular membrane
10. " Smoky" turbidity in gross examination of urine
is often seen with what condition? E. AOTSAT
A. Acute glomerulonephritis
B. Cholesterol droplets 15. Which part of the kidney is the Tamm- Horsfall
protein secreted?
C. Renal tubular epithelial cells
A. Thin Ascending LOH
D. Uric acid Crystals
B. Distal convoluted tubule
E. Calcium Oxalates
C. Thick Ascending LOH
A. Rbc Cast
16. This condition is frequently seen in children
B. Hemoglobin casts which is a recurrent infection of the renal tubules
caused by structural abnormalities
C. Muddy brown cast
A. Chronic glomerulonephritis
D. Both B and C are correct
B. Chronic Pyelonephritis
E. NOTA
C. Nephrotic Syndrome
D. Nephritic Syndrome
13. A 16 year old male presence with fever,
periorbital edema, fatigue, oliguria and hematuria. E. Minimal change Disease
Significant history noted a throat infection two
weeks prior to onset of symptoms. Which of the
following statements is not TRUE for the said 17. Renal Tubular epithelial cell casts are seen in the
pattern? following conditions, except
A. Primary urinalysis findings include RBC A. Acute Tubular Necrosis
casts dysmorphic RBCs, hyaline and
granular casts and WBC B. Ethylene glycol poisoning
C. Pregnancy
D. Menstruation
E. NOTA
C. Cytoplasmic bodies
c. 15-25 ml b. LPO
d. 50 ml
c. HPO
d. OIO
3. To correct for differences in the diameter of
centrifuge heads, ____ should be used in
centrifugation.
9. Reported in average number per low power field
a. RPM
b. RCF a. casts
c. RCP b. WBCs
d. RPS
c. RBCs
d. Epithelial cells
4. The unwanted dilution of urine sediments could
give a ____ result:
a. false-positive 10. Reported in semi-quantitative terms per low
power field
b. true-positive
a. casts
c. false-negative
b. WBCs
d. true-negative
c. RBCs
5. Centrifugation that produces an optimum amount
of sediments with the least chance of damaging the d. Epithelial cells
elements is performed for
14. All are parts of the lens system, except: b. Dark-field microscopy
15. The object's total magnification using high 19. The image has the best contrast when the
power objective with an ocular lens magnification of background is at its darkest.
10x.
a. Bright-field microscopy
a. 40x
b. Dark-field microscopy
b. 100x
c. Polarizing microscopy
c. 400x
d. Fluorescence microscopy
d. 1000x
e. Phase-contrast microscopy
f. Interference-contrast microscopy
16. It provides three-dimensional images with fine
structural details.
f. Interference-contrast microscopy
b. 12ml
7. What finding facilitates localization of infection
c. 5ml
in the kidneys instead of the lower urinary tract?
d. Any volume will do provided that proper
a. Nitrites
centrifugation time and speeds are followed
b. Positive urine culture for E. coli
c. Leukocyte esterase
2. Which of the following sediments are expressed
semi-quantitatively? d. WBC Casts
a. Crystals
c. Waxy cast
3. Which of the following is not supportive of a
microscopic finding of bacteriuria? d. All of the above
a. Ph of 3.0
c. Hypercholesterolemia
4. What is the most frequently used stain in d. All of the above
urinalysis?
a. Hansel stain
10. What is the most common parasite encountered
b. Prussian blue stain in urine?
c. Oil Red O a. E. vermicularis
d. Sternheimer-Malbin Stain b. S. hematobium
c. T. vaginalis
5. Drug-induced interstitial nephritis may best be d. All of the above
elucidated by what stain?
a. Hansel stain
11. Which of the following parasites can be
b. Prussian blue stain encountered in urine?
c. Oil Red O a. E. vermicularis
d. Sternheimer-Malbin Stain B. S. hematobium
C. T. vaginalis
6. What substance makes up casts? D. All of the above
a. Uric acid
b. Cylindruria
18. The presence of dysmorphic RBCs is indicative
c. Bacteriuria
of damage localized to:
d. None of the above
a. Proximal tubules
b. Loop of Henle
13. What crystal is not necessarily a cause for
c. Urinary bladder
concern when seen under microscopic exam?
d. Glomerulus
a. Cystine
b. Uric Acid
19. This is a large polygonal cell with abundant,
c. Leucine
dense cytoplasm and a prominent nucleus that is
d. Bilirubin covered in some portions by coccobacilli.
a. Clue cell
C. Uric acid
20. Clue cells represent colonization of squamous
D. Ammonium biurate epithelium by what organism?
a. Gardnerella vaginalis
c. Bilirubin
a. Cholesterol
b. Cystine
c. Resazurin
d. Tyrosine
B. Pia mater
7. The reason why nucleated RBCs are seen in the
C. Choroid plexus CSF
B. Chemistry
8. Hemosiderin granules and hematoidin crystals
C. Microbiology are seen in:
D. Hematology A. Lymphocytes
B. Macrophages
C. -20°C
9. The reference range for CSF protein:
B. 2-4°C
A. 15 to 45 mg/dL
D. -80°C
B. 6 to 8 mg/dL
C. 15 to 45 g/dL
4. What does a web-like pellicle in a refrigerated
D. 6 to 8 g/dL
CSF specimen indicates?
A. Viral meningitis
10. In serum, the second most prevalent protein is
C. Primary CNS malignancy
IgG; in CSF, the second most prevalent protein is:
B. Multiple sclerosis
A. Transferrin
D. Tubercular meningitis
B. IgA
C. Prealbumin
5. A total CSF cell count on a clear fluid should be:
D. Ceruloplasmin
A. Not Reported
C. Multiple sclerosis
C. 120 mg/dL
18. The reference concentration of a normal CSF
B. 60 mg/dL glutamine:
D. 20 mg/dL A. 8 to 18 mg/dL
C. 8 to 18 g/dL
A. Viral meningitis
19. Organisms frequently encountered in a
B. Bacterial meningitis bacterially infected CSF:
C. N. meningitidis
A. RPR
20. The functions of the CSF include all of the
B. VDRL following:
B. WBCs
C. Bacteria
D. Protein
A. Cerebral hemorrhage
B. Acute leukemia
D. Metastatic carcinomas
A. CSF leakage.
B. Neurosyphilis
TOPIC 9: SEROUS FLUIDS Klebsiella pneumoniae
1. What is the preferred method for diagnosis of
Bacillus anthracis
spontaneous bacterial peritonitis
Neutrophil count
7. What cells are increased in pulmonary infarction
Acid fast staining
Neutrophils
Cholesterol level determination
Monocytes
Fibronectin level determination
Lymphocytes
Eosinophils
2.What is useful in documenting hemorrhagic
effusions
Lipids
3.What test is useful in diagnosing lupus pleuritis
ADA test
9.Pleural fluid is characterized by which of the
ANA test
following
Glucose test
Does not clot
C-reactive protein test
Eosinophilia is common
Feculent
4.Which is decreased in pleural fluid exudate
Lymphocytes predominate in early TB
Pleural fluid LD
72 hrs
96 hrs
36 hrs
120 hrs
Streptococcus pyogenes
Staphylococcus urates
A.Gram Stain: Sodium Polyanethol Sulfonate
C. Low
3. Which of the following tests below is commonly D. Poor
performed on synovial fluid?
A. Gram Stain
9. In what squares should WBCs be counted in a
B. Rope Test cloudy, green synovial fluid with a clinical
impression of septic arthritis:
C. WBC Count
A. All 9 large squares
D. Crystals Examination
B. 5 small squares in the central large square
A. Non-inflammatory
11. Poor arthrocentesis technique is expected to
B. Inflammatory show plenty of which types of cells?
C.Septic A. Reiter Cells
D.Hemorrhagic B. Ragocytes
C. LE Cells
6. What test is not properly matched to the D. Synoviocytes
anticoagulant that should be used?
A. Crystal violet
C. LE Cells
18. The presence of neutrophils in the intestinal
D. Synoviocytes epithelium is specific for an infectious process:
A. True
A. Nephrotic Syndrome
19. A black stool can be explained by:
B. Traumatic Injury
A. Bleeding in the stomach
C. Acute inflammation
B. Ingestion of activated charcoal as treatment
D. All of the above for poisoning
C. Iron megadosing
A. Negative birefringence
20. Cholera is characterized by what type of
B. Positive birefringence diarrhea?
C. Either A. Secretory
D. Neither B.Osmotic
C. Dysentery
A. Negative birefringence
B. Positive birefringence
C. Either
D. Neither
A. CPPD
B. MSU
C. Cholesterol
D. Calcium oxalate
Column A Column B