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400 B.C.

EBERS PAPYRUS
➔ Oldest preserved egyptian compilation
HIPPOCRATES of medical texts.
- a greek physician. ➔ contains a description of the 3 stages
- founder of science medicine. of hookworm.
-formulated the famous HIPPOCRATIC OATH. 3 STAGES OF HOOKWORM
● EGG
HIPPOCRATIC OATH ● LARVAE
- code of ethics for practicing physician. ➔ FILARIFORM
➔ RHABDITIFORM
4 HUMOURS ● ADULT
● BLOOD
● PHLEGM MEDIEVAL PERIOD (1098 - 1438)
● YELLOW BILE
● BLACK BILE RUTH WILLIAMS
NOTE: Urine was the composite of these - Believed that medical technology
humors. began from the medieval period.
ANNA FAGELSON (ANNE FAGELSON)
URINALYSIS - Confirmed the beginning of medical
- the study of urine technology when she correlated the
- oldest laboratory procedure death of Alexander Gillani to
laboratory-acquired infection.
600 B.C.
- physicians recorded the taste of diabetic urine 17th CENTURY
- if ants gather, the urine is sweet
ANTON VAN LEEUWENHOEK
1500 B.C. - FATHER OF MICROBIOLOGY
- First scientist who used compound
VIVIAN HERRICK microscope
- traced the beginning of medical technology - Observe and describe the appearance
when intestinal parasites such as TAENIA and of RBC and differentiate bacteria using
ASCARIS were first identified. the compound microscope.
MARCELLO MALPIGHI
NOTE: TAENIA is a kind of flatworm. - “FOUNDER OF PATHOLOGY”
ASCARIS is a kind of roundworm. because of his contributions to
embryology and anatomy.
2 TYPES OF TAENIA - Greatest of the early microscopist.
● TAENIA SODIUM - gets by eating
undercooked pork. 18th CENTURY
● TAENIA SAGINATA - gets by eating
undercooked beef. RUDOLF VIRCHOW
ASCARIS - soil transmitted. (transmitted primarily - FATHER OF MICROSCOPIC
by walking barefoot on contaminated soil). PATHOLOGY
- Also gets by eating and drinking - Emphasized the study of diseases and
contaminated foods and water. infections which are visible at the
cellular level by means of microscope.
MICROSCOPIC PATHOLOGY - cellular level
of disease
19th CENTURY 1920
- employment increased to 3,500
LOUIS PASTEUR
- Discovered the concept of anaerobic 1922
and aerobic bacteria. - 3,035 hospitals had clinical laboratories
ANAEROBIC BACTERIA - do not need
oxygen to survive. WORLD WAR 1
AEROBIC BACTERIA - needs oxygen to - important factor in the growth of clinical
survive. laboratory
FACULTATIVE - they may or may not need - produced great demand for technicians
oxygen to survive. 1 REASON
● FACULTATIVE ANAEROBIC - need a - BIOTERRORISM
little carbon dioxide to survive.
● FACULTATIVE AEROBIC - need a UNIVERSITY OF MINNESOTA
little bit of oxygen to survive. - one of the first schools where training
workers was established
HISTORY OF MEDICAL TECHNOLOGY IN - the course bulletin was entitled “
THE UNITED STATES “COURSES IN MEDICAL TECHNOLOGY
FOR CLINICAL AND LABORATORY
1885 TECHNICIANS “ (1922)
DR. WILLIAM H. WELCH
- first professor of pathology at John 1921 - THE DENVER SOCIETY OF
Hopkins University CLINICAL PATHOLOGIST WAS
ORGANIZED.
1896
- the first clinical laboratory was opened at MEDICAL LABORATORY BOARD RATING
the JOHN HOPKINS HOSPITAL by DR. - 75 and above
WILLIAM OSLER.
- a clinical laboratory was also opened at the LABORATORY TECHNICIAN BOARD
UNIVERSITY OF PENNSYLVANIA RATING
(WILLIAM PEPPER LABORATORY). - 71 to 74 percent

DR. JAMES C. TODD 1923


- wrote “ A Manual of clinical diagnosis ” - the university of Minnesota was the first to
- retitled “ Clinical Diagnosis by offer level program
Laboratory Methods “ in the 19th edition
WORLD WAR 2
1900 - CENUS - era of sophistication
- 100 male technicians were employed in the - blood usage increased
united states - close system of blood collection was widely
adopted
1915
- the state legislature of Pennsylvania BODY SYSTEM
enacted a law requiring all hospitals and - soldiers should have a partner with the
institutions to have an adequate lab and to same blood type
employ a full time laboratory technician.
OPEN SYSTEM
- greater risk of infection
- no safety procedures in blood transfusion
Mrs. Willia Hedrick (MRS. WILLA
DEVELOPMENT OF MEDICAL HEDRICK)
TECHNOLOGY IN THE PHILIPPINES - founder of the medical education in the
Philippines
1944
- the first clinical laboratory in the Dr. Reuben Manalaysay
Philippines was built at Quiricada St., Sta. - president of the Philippine Union College
Cruz Manila by the 6th Infantry Division of
the U.S. ARMY Rev. Merrit Warren
- now known as the MANILA PUBLIC - president of the North Philippines Mission
HEALTH LABORATORY of the 7th day Adventist

JUNE 1945 3 MAJOR COURSES


- the 6th US army left the place leaving the - Microbiology
laboratory to the NATIONAL DEPARTMENT - Parasitology
OF HEALTH which is now known as the - Histopathology
DEPARTMENT OF HEALTH (DOH) - back then, it was a 5 year course
- now it consists of 4 years (3 years for
Dr. Alfredo Pio De Roda acads, 1 year for internship)
- a well known filipino Bacteriologist
- preserved the remains of the facility March 1956
together with Dr. Mariano Icasiano - when the PUC had its 1st graduate which
is Dr. Jesse Umali
Dr. Mariano Icasiano - followed by Mr. Avelino Oliva and Ms.
- 1st city health officer of Manila Adoracion Yutuc

October 1, 1945 1957


- the preserved laboratory was formally - University of Santo Tomas (UST) offered
established by Dr. Alfredo Pio De Roda a course in Pharmacy
with the help of Dr. Prudencio Sta. Ana - leading to a Bachelor of Science in Medical
(DR. PRUDENCIA STA. ANA). Technology course under Dr. Antonio
- both of them offered free training Gabriel and Dr. Gustavo Reyes

1947 JUNE 1960-1961


- the Public Health Laboratory and Manila - Bureau of Education approved the 3 year
Heath Department started training medical technology course
laboratory technicians - 4th year as internship program

1954 Centro Escolar University (1960)


- Dr. Alfredo and Prudencio together with Dr. - offered the degree of B.S. Medical
Tirso Briones prepared a syllabus for Technology
training medical technicians - turned out the first batch of graduates in
- Manila Sanitarium Hospital and Philippine 1962
Union of college opened the first medical
program in the Philippines FAR EASTERN UNIVERSITY (1961)
- started the school of Medical Technology
- started with the combined efforts of Dr. - produced diseases in worms by injecting
Horacio Ylagan and Dr. Serafin Juliana organic material
- granted by Dr. Lauro Panganiban and Dr. - IMPACT OF CONTRIBUTION:
Jesus Nelasco BACTERIOLOGY

Dr. Horacio Ylagan 1857


- technical director of Far Eastern University
LOUIS PASTEUR
UNIVERSITY OF THE PHILIPPINES (1961) - produced immunity to rabies
- offered B.S. IN HYGIENE (B.S. IN PUBLIC
HEALTH) 1866

GREGOR MENDEL
MILESTONES IN MEDICAL - proposed his law of inherited characteristics
TECHNOLOGY from studies on plants

1660 1870

ANTON VAN LEEUWENHOEK JOSEPH LISTER


- FATHER OF MICROBIOLOGY - father of modern surgery
- Known for his work on improvement of - described that surgical infections are caused
the microscope. by airborne organisms
1796
1877
EDWARD JENNER
- Discovered vaccination to establish ROBERT KOCH
immunity to small pox. - presented the 1st pictures of Bacilli and
IMPACT OF CONTRIBUTION: Tubercle Bacilli
IMMUNOLOGY BACILLI - anthrax ( respiratory infection)
Also known as WOOLSHORTER’S
Small Pox DISEASE
- cross reactive to cow pox - used as bioterrorism
- fatal
1886
Cow Pox
- less fatal ELLIE METCHNIKOFF
- less symptoms - described phagocytes in the blood and their
role of fighting infections
1880
PHAGOCYTES
MARIE FRANCOIS XAVIER BICHAT -like
- Identified organs by the types of - type of white blood cell
tissues. - engulfs foreign materials - bacterias, viruses
IMPACT OF CONTRIBUTION: HISTOLOGY
PHAGOCYTOSIS
1835 - process of engulfment from foreign material.

AGOSTINO BASSI ERNST VON BERGMANN


- introduced steam sterilization in surgery
AUTOCLAVING - process of sterilizing the 1954
material through steam under pressure.
JONAS SALK (through intramuscular)
1902 - Developed poliomyelitis
vaccine.
KARL LANDSTEINER
- father of blood groupings POLIOMYELITIS
- father of immunochemistry - virus that infects the nerve cells inside the
- distinguished the development of ABO Blood muscles.
Group System INTRAMUSCULAR
- arm vaccine
TWO MAJOR BLOOD TYPES
ALBERT SABIN
1. ABO - TYPE A, B, AB, O - ORAL POLIO VACCINE
2. RHO - TYPE A+, TYPE B+ (BASTA MAY - matter of demonstration is through
PLUS) oral.
ORAL - mouth
1906
1973
AUGUST VON WASSERMANN
- Developed immunologic tests for JAMES WESTGARD
syphilis - Westgard rules
SYPHILIS- sexually transmitted disease. - Rule for the quality control in the clinical
VERTICAL TRANSMISSION - transmission laboratory
of disease during pregnancy (kung saan
naipapamana ang syphilis sa magiging anak). 1980

HOWARD RICKETTS BARUCH SAMUEL BLUMBERG


- Discovered microorganisms whose - introduced Hepatitis B Vacinne
range lies between bacteria and virus
called RICKETTSIAE. HEPATITIS B
- liver infection
RICKETTSIAE - microorganism that lies
between the bacteria and virus. 1985
- can infect inside the cell.
KARY MULLIS
1929 - Developed the polymerase chain
reaction (PCR).
HANS FISCHER - Antigen test
- worked out the structure of hemoglobin
1992
HEMOGLOBIN (SABI NI GOOGLE
HAEMOGLOBIN) ANDRE VAN STEIRTEGHEM
- carries oxygen - Introduced intracytoplasmic sperm
- present in the red blood cell (RBC) injection (IVF).
1998

JAMES THOMSON
- derived the 1st human stem cell line

STEM CELL
- 1st line of cells
- can be transfused if compatible

By: MLS BLOCK 1F


Andrei B. Baccay
Brent Ivan D. Suero

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