Internal Assessment Examination – 1 2022 Batch

Pharmacology – General Pharmacology Theory

Multiple choice questions: (10x 1 = 10 marks)

1.An 'orphan drug' is:

A. A very cheap drug
B. A drug which has no therapeutic use
C. A drug needed for treatment or prevention of a rare disease
D. A drug which acts on Orphanin receptors

2. Drug administered through the following route is most likely to be subjected to first-pass
metabolism:
A. Oral B. Sublingual C. Subcutaneous D. Rectal

3. High plasma protein binding:

A. Increases volume of distribution of the drug B. Facilitates glomerular filtration of the drug
C. Minimises drug interactions D. Generally makes the drug long acting

4.When the same dose of a drug is repeated at half life intervals, the steady-state (plateau)
plasma drug concentration is reached after:
A. 2–3 half lives B. 4–5 half lives C. 6–7 half lives D. 8–10 half lives

5. The name accepted by a competent scientific body/ authority is called as:

A. Chemical Name B. Non- Proprietary name C. Brand Name D. Proprietary name

6.Which of the following types of drug metabolizing enzymes are inducible:

A. Microsomal enzymes B. Nonmicrosomal enzymes
C. Both microsomal & non microsomal enzymes D. Mitochondrial enzymes

7. As per drugs and cosmetic act prescription drugs are included in

A.Schedule C B. Schedule H C.Schedule P D.Schedule X

8. Which of the following is a prodrug:

A. Hydralazine B. Clonidine C. Captopril D. Enalapril

9. Drug excreted in saliva is

A.Tetracycline B.Lithium C.Ampicillin D. Chloramphenicol

10.All the drugs except one cross the Blood brain barrier:

A.Morphine B. Dopamine C.Propranolol D. Ether