You are on page 1of 1

This loss can be produced via two ways:

1.Dimish feeding
2.Increased lypolisis
The hypotesis presented in this The common denominator sums up to be
document brings up that hydration can angiotensin II wich is the a hormone that
lead to body weight loss due to a regulates de body fluid and stimulates
decrease in feeding and fat loss thirst.Also increases the apetite for sodium,
through increased lypolisis. and realeses vasopressin to conserve water
via the kidneys. .

Increased hydration can be


associated
CENTRAL AngII,DRINKING AND
RAS "KNOCKOUT" MICE
DRINKING AND WEIGHT LOSS with weightloss WIGHT LOSS
-Mice with the renin gene knoked out seem to
drink copiusly, are hyperactive, thin and AngII administrtion
present low body fat and as a favorable result increases water intake on
they don´t develop obesity with no water animals.
RAS ANTAGONISTS DRINKING It was noted that intracranial
intakes.
AND WEIGHT LOSS
-Angiotensin-deficient mice exhibit weight AngII had an effect of less
RAS inhibitors are renoprotective, reduce feeding after drinking
loss and body fat with a rise in activity.
obesity and can improve insulin sensitivity in
-The knockout of ACE on mice increased IChronically administrated AngII
rodents without water intakes and
water intake anddecreased their body weight increased water consumption,
paradoxicaly RAS blockade can increase
and body fat. resulting on weight loss , mostly
drinking in response to increased-blockade
fat loss.
urine flow.

You might also like