GENERIC NAME: CLASSIFICATION INDICATION: MECHANISM CONTRAINDICATIONS: SIDE EFFECTS: NURSING

- Mefenamic Acid AND CATEGORY: For the treatment OF ACTION: Hypersensitivity to Most common CONSIDERATIONS:
of rheumatoid It is an NSAID drug/class/component. side effect may The nurse should follow
BRAND NAME: A. CHEMICAL: arthritis, (Non-steroidal NSAID-induced asthma include nausea, the prescribed dosage
- Dolfenal Mefenamic acid osteoarthritis, anti-inflammato or urticaria, aspirid triad, pale skin, severe and schedule strictly.
AVAILABLE DOSAGE: (also known as dysmenorrhea, ry drugs) and Pregnancy 3rd trimester, stomach pain, Mefenamic acid should
- 250mg, 500mg Arthranilic Acid) and mild to used as an renal disease, CABG cramping, be taken with food or
ROUTE: moderate pain, analgesic in (Coronary artery bypass heartburn, bloody milk to minimize
- Oral B. THERAPEUTIC: inflammation, and treatment of graft) surgery periop use, urine, lower back gastrointestinal upset in
FREQUENCY: 1 tablet treat mild to fever. painful Active PUD (Peptic ulcer or side pain, patient.
every 8 hours, as moderate pain musculoskeleta disease). indigestion
needed or as directed (Gastrointestinal l problems, The nurse should
by physician Cramps) ( Primary chronic JRA ADVERSE assess and obtain the
Dysmenorrhea) (Juvenile REACTIONS: patient his/her medical
PREPARATIONS: rheumatoid Common history, including
Dolfenal is available in C. PREGNANCY arthritis). reactions include allergies, current
various preparations, CATEGORY: you dizziness, medications, pregnancy
such as tablets and should not take dyspepsia, rash, or breastfeeding.
capsules, with different mefenamic acid peripheral
strengths ranging from unless your doctor edema,
250 mg to 500 mg. The tells you to. constipation
specific formulation and Serious reaction
dosage will depend on may include
the medical condition hypertension, GI
being treated. Bleeding,
thromboembolis
PHARMACOKINETICS: m,
Mefenamic acid is Steven-johnson
metabolized extensively syndrome,
in the liver, about 52% anemia.
of dose of mefenamic
acid is excreted in urine
as glucoronic acid,
conjugates of the drug
and its metabolites.
About 20% of a dose is
excreted in feces.
Mefenamic acid is
apparently not
dialyzable.

ONSET: Rapid
 PEAK: Usually reached
within 2 to 4 hours after
administration

DURATION: The
duration of action can
vary but generally lasts
for about 6 to 8 hours.

HALF LIFE: 2 hours

Source:
https://www.muramed.com/store/detail/dolfenal-250-mg-tablet
https://www.pediatriconcall.com/drugs/mefenamic-acid/739