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  • BIOS-251 Anatomy and Physiology With Lab Self-Test (44) - F

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    Allergens stimulate B cells to secrete IgE antibodies which then bind to mast cells, sensitizing them. On subsequent exposure, the allergens cross-link the IgE antibodies on mast cells, activating them and causing the release of inflammatory molecules from granules. This cross-linking of IgE antibodies on mast cells by allergens triggers type 1 hypersensitivity reactions.

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    BIOS-251 Anatomy and Physiology With Lab Self-Test (44)_f

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    Allergens stimulate B cells to secrete IgE antibodies which then bind to mast cells, sensitizing them. On subsequent exposure, the allergens cross-link the IgE antibodies on mast cells, activating them and causing the release of inflammatory molecules from granules. This cross-linking of IgE antibodies on mast cells by allergens triggers type 1 hypersensitivity reactions.

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    3 views1 page

    BIOS-251 Anatomy and Physiology With Lab Self-Test (44) - F

    Uploaded by

    kariukisimonmerit
    Allergens stimulate B cells to secrete IgE antibodies which then bind to mast cells, sensitizing them. On subsequent exposure, the allergens cross-link the IgE antibodies on mast cells, activating them and causing the release of inflammatory molecules from granules. This cross-linking of IgE antibodies on mast cells by allergens triggers type 1 hypersensitivity reactions.

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    © All Rights Reserved
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    of 1

    releases cytokines.

    The cytokines then stimulate differentiation and proliferation in the IgE-


    secreting plasma cells. The IgE antibodies then bind to mast cells, sensitizing them for
    subsequent exposure to the allergen. On second exposure, the allergens cross-links IgE
    antibodies on the mast cells causing activation. This then releases granules and inflammatory
    molecules that causes signs and symptoms type 1 hypersensitivity reactions

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