DAWIS NATIONAL HIGH SCHOOL

SCIENCE 10- Weeks 4-5 Summative Test

Name: ______________________________________ Score:_____________________________

Grade & Section: ______________________________

I. Multiple Choice (1 point each item)

Choose the letter of your best answer and write on the space provided.
_______1. Which of the following is NOT a characteristic of DNA?
A. double stranded C. Most of DNA is found inside the cell nucleus.
B. Uracil is paired with adenine. D. Adenine and guanine are under the same family.
_______2. What is the base pair of cytosine in RNA?
A. adenine B. guanine C. thymine D. uracil
_______3. Which of the following statements is NOT correct?
A. In RNA, adenine and guanine are under the same family.
B. DNA has 4 nitrogen bases, phosphate groups, and sugar called deoxyribose.
C. RNA is the primary genetic material that is used to create amino acids in the process of protein
synthesis.
D. DNA and RNA are nucleic acids that both have sugars, possesses four nitrogen bases, and has
phosphate groups.
_______4. Which would explain why DNA is often referred to as the code of life?
A. It has a double helix structure.
B. Its molecule is made up of phosphate, sugar and a base.
C. Its molecule is packed into chromosomes.
D. It acts as a type of chemical code that contains instructions known as genes.
_______5. Which statement correctly describes the DNA molecule?
A. A single strand with bases bonded to phosphates and deoxyribose sugars.
B. A double strand like a ladder with uprights made of bases and rings made of phosphates and
deoxyribose sugars.
C. A double strand like a ladder with uprights made of phosphates and deoxyribose sugars and rings
made of bases.
D. A double strand like a ladder with uprights made of bases and phosphates and rings made of
deoxyribose sugars.
_______6. Complete the Venn diagram on the right side
where DNA and RNA have their similarities.
A. Adenine, thymine, phosphate groups, sugar
B. Adenine, guanine, cytosine, phosphate groups, sugar
C. Adenine, uracil, cytosine, phosphate groups, sugar
D. Adenine, guanine, cytosine, thymine, nitrogen bases
_______7. Which of the following enzymes that is also called as the builder?
A. DNA polymerase B. helicase C. ligase D. primase
_______8. Which of the following is involved in the process of protein synthesis?
A. replication and mutation C. transcription and translation
B. replication and transcription D. substitution and inversion
_______9. What do you call the process of duplicating the DNA producing two identical copies?
A. Replication C. Transcription C. Translation D. Transpiration
_______10.What codon which is usually the first codon of mRNA?
A. ACG B. AUU C. AUA D. AUG
_______11. Which of the following is not part of DNA replication?
A. The enzyme helicase breaks the bond between nitrogenous bases.
B. DNA polymerase adds the complementary nucleotides to form new strands.
C. Messenger RNA enters to the nucleus and carry protein information from the DNA back to the
cytoplasm.
D. The broken nitrogenous bases attached to each of the strands will be paired up with the free
nucleotides which will be glued after by ligase.
_______12. From which code will be used in translating to amino acids?
A. DNA transcription B. Original copy of DNA C. mRNA or codon D. tRNA or anticodon
_______13. What is the purpose of a DNA primase?
A. To unwind the double helix. C. To build the daughter strand of DNA.
B. To terminate the process of DNA replication D. To initiate the process of DNA replication.
For items 14-16. Use the codon chart to translate the codes into its specific amino acids. Complete the
needed data below for you to answer the following items below.
DNA: TAC CAT GAA CTA
Transcription: ATG GTA CTT GAT
mRNA: ______________________
tRNA: ______________________
Amino Acid: ______________________
_______14. Which of the following codes below that
has the correct sequence of mRNA?
A. UAC CAU GAA CUA
B. UAC CAU UGA CCG
C. UAC GCU GAU CAU
D. UAC GCU GAA CUA
_______15. Which of the following codes below that
has the correct sequence of anticodon?
A. AUG GCA CUU AAG
B. AUG GUA CUA GAC
C. AUG GUA ACU GGC
D. AUG GUA CUU GAU
_______16. What is the correct sequence of amino acids in the given data above?
A. tyrosine , threonine, proline , leucine
B. tyrosine, histidine, leucine , aspartic acid
C. tyrosine , glutamic acid, valine, glycine
D. tyrosine, histidine, glutamic acid, leucine
_______17. Which of the following statement below is NOT correct?
A. Each codon encodes a different amino acid.
B. Every sequence of protein starts with methionine.
C. Only one start codon marks the beginning of protein.
D. Codons like UAA, UAG, and UGA triggers the end/stop of protein synthesis.
_______18. Which of the following statements is CORRECT about threonine amino acid?
A. It has four different codes, ACG, ACA, ACU & AGA.
B. Third nitrogen base of ACG code can be substituted with A, C, & U.
C. It is impossible for substitution mutation because it will result to another amino acid.
D. It has a unique codon sequence which can be translate only with one code which is ACG.
_______19. Which of the following is NOT part of chromosomal mutation?
A. deletion B. inversion C. substitution D. translocation
_______20. Which type of gene mutation that are generally much more serious and often more deadly
than other type of mutations because of its types which are deletion and insertion?
A. chromosomal mutation B. frameshift mutation C. point mutation D. structural mutation
_______21. This type of genetic disorder is also called as trisomy 21.
A. Cri du chat B. Down syndrome C. Edwards syndrome D. Jacobsen
_______22. Which of the following sequence that shows insertion type of mutation?
Original Sequence: AUG CCG UGA
A. AGC CGU GAA B. AUG CGC UGA C. AUG CGU GAA D. AUG CAC GUG
_______23. What type of chromosomal mutation happens in the picture on the right side?
A. deletion B. inversion C. substitution D. translocation
______ 24. Which of the following gene mutation will result to a shortened arm of
chromosome?
A. deletion B. inversion C. substitution D. translocation
______ 25. Which of the following statements follows the silent mutation?
A. When the amino acid is changed into a new one.
B. When one of the nitrogen bases is being removed.
C. When the result of substitution of base does not change the amino acid.
D. When the result of substitution changed the amino acid into a stop codon.
______ 26. A man has enlarged breasts, spare head on body and sex complement as XXY. He suffers from:
A. Edward’s syndrome B. Turner’s syndrome C. Down’s syndrome D. Klinefelter’s syndrome.
______ 27. In a family, a father is having a disease and the mother is normal. The disease is inherited to
only daughters and not to the sons. What type of disease is this?
A. Edward’s syndrome B. Down’s syndrome C. Turner’s syndrome D. Klinefelter’s syndrome.
For items 28-30. Use the data below.
Original Sequence:
mRNA: AUG GGA UGU UGA
Amino Acid: Met. Gly. Cys. Stop
Mutated Sequence:
mRNA: AUG GGC UGU UGA
Amino Acid: Met. Gly. Cys. Stop
______ 28. What is the type of mutation?
A. deletion B. inversion C. substitution D. translocation
______ 29. Which of the following best describe its type of mutation?
A. It follows the inversion type of chromosomal mutation.
B. It is deadly mutation since it changes almost all of its amino acid.
C. Deletion type of mutation where A is removed and replaced with C.
D. It is a silent type of substitution since it does not change the amino acid after being mutated.
______ 30. What is the correct mutation analysis of the given sequence.
A. Frameshift , substitution, amino acid changed.
B. Point , substitution , no change
C. Frameshift, deletion , changed to stop signal
D. Point, deletion, no stop signal

Prepared by:
JAIME S. CRISPINO
Science 10 Teacher