D X

D X

E8
O
O
X
O
O
producesmelanin Dopa
eINE
o
c
x
O bytrp

D
T
Yoxisation
0

A 8
O
Xketobodies
primary

liver
x
majin
af
T

T
O
O

Ag

8
88

a8 E
I
x
x x
x

x Impsonotsynthesis
O Amy

O
x
x
x
x
f
O x
x
x
x

0
X
x
x
x

O
 I

0
Y x

O
 O
O
Eq
O
Bo

8
O r
o
A 8Trease r
e8 r
r

A8 r
A 8
chylomicron
__

I reversecholesteroltransport
 o

Teased

I
C

X
 ANSW[R

a:
A It 1 lHe NL X1 QUI!
if 1::·a~: J•nr1 3rd
c. if 2nd qnd
-~,~s~~~:saUV USING 1 ME kL" .
4th ,.._ttt
. rd atnt!Jmonta :t ro c:ortc1;t
ro corl'\lct.
0 . If only tho 41h monts artJ corroct
E. If all atatomon:tntttmont lo c:on~ct.
Dru corroet.
1 IN ·1 Ill l t\
i!;>,; 11 \~1 l!-iO Sl ,11 1 l lJC \(h
I lh 'I R IJR ,u,roc,,1
2 ~ 1Y[~r!Q411Jt or ~:nn,110 I ~11/\~, s.
O
3 lite n c •.avd1c• •Yrrth~h c ta 1•t111dt1 l)ntl ,
\1,-,
if the J)ICU1u11 of fi.rw11cuJ • lllbtt
2 O
WH1c;:"'~1•1n of Cfl?rrn,-,1 ll~J ~;;7,)111~, lik't ,,"(Cll•Co,4, .:;aiho"\-.c And.Iii QC

I
J th OJ JU! I ntLQ\\ I~< r alt) iii;id l-i=-tll•o\.i.1111100

8i
C) lte S}'mliCl.11(:d UI
lhc uulu.at1un oJ k:tt011t bod
a i:,:nif'ff:am portioo ot
l'A1£t,..1t N'i IS (AIU ) ll\\ I H'm IJ'Ul :).\ ~'THI ..,h'
aflcr Mlo ,2 !loin 1-i:lo\\ing tilt lll~ fo,'4 Q'f!C:ib
dt y c,,.1r,bc,>.iuc ••»uel
TOQUll·o w.:~I "n,\
, c'.:f Bi N

3 WH~liai, o of Ui&hl:c:ride1 ;to :-) bu?

nnc .ind lM:<'fi)&.'flQ.t, Ii M1lit~ In 1t1t1 bnlll'I
I ~-i =~NT(S) JS J\.IU \'R~~1r. ,1dtJX')(')tt'\ l\ urc-4 t.'tt tlldr ~}'l\~i
1 TNhl;,hi lfCU:~i::,i;: •• tu trutllrt~ the uptake of glu,c.ow ftfo imulm • ~ t ,,
O pmaia (PPA_R£Alnru~ghe.s dQ:\l,1\·IC,~ll.t4'S lrnnMlfllllll'llu.l 1chyjl) 1lf 1--~l.llITTfl'<! rX0
C 3. PPAR~ltllelnd PPAR l t\ Y~hlcadi~t•~
has am,~infillm"I jiha £mcrally c.nh:1n~c tl1c n,li: c,f f•ll} 1,id i)11th~ux
4 O
4
lXS\,."L{N lNDlJC£S ~ator) IIU)(f rrnmunc ~1,1pprcs,sm1 ~ r t C$ u
l pha.-.phocoofrAntvatrn::~~.SS10N OJ· 1Hl:) I 01 LO\\ INU ill:NI fS) IN wn l fU'I ,\jfi
., , ,.., c .._._...,..nwe
:- ..-Co.A cm:bc7:rylasc: x
.,,~~
c,.~lzsmit, liMO::CuA reduaase
S FOB. TITEBETA-OXIDAllON OFPALMtl \'ffi(Cl6)
beta-m:~,mr 11 hydraucm ofthc tr: ru-doublc boM, fi1mung :l l..:h~\''!t· )'\ t'M,
2 whl~ IJ used for cnerap production
3 mz;)'l:1~ FADif: t."lltUfcn dc~1l'Of1~ l,O l:.'U·:.00 lclWrt,tl ltlll1)ll!r n11Y\'f)l\lh 1n.C.ot} Mt,l~k 1li11f!)
WJ!J l!sorcsw: m proplon)i-CoA fonn.1ulon
5 iH£ :F0UO\\'.mG AMJN'O ACID(S) II<; AJlli N0NIR0 rEJ~OOl~t< ,\ MlNO J\O11('-l
o
1 !)..Allpllr.n
.:ci:1::-n~

8O
5 O:nifuine
- Aq:mintl$UCQllSU:
- \\ID~lS .AMMON
lti 1hr 111Jt1CY1C ,_,.....,...ian
XIC'I
(~c, n,d1c11I podU1.1m11 a11d dat11fltc
O
2. Out! 10 IDC'n::akd OD X
- IJ dtl.5CS a l ; m n ~ dq:,ledon throu~h dlr o«Iotr of glullunm dchvdro~n!U\':
O
4 Dur wilht r ~.;,:;:rz:n1dmc ~y¢Jcm
5 ..:"!UC .AClID

O
EO
m the- :bk,"~
ryn:JWintouJZe
hi_dJ J:P gout-plli.lent:, r
avsi,11,h uv (om, dcponls fn the Jomts
o :u=J~) 11n afrcr rndiodlempy {tunulf ly•i, &) udtmnc)
o 'iMND ACW&OKBONES
l!f~.mds pra-,cintypb.I}yaoout lO•I.S~ orthc rcqul.ml enc~ \n the human~~

BO ~ .D fonh .s!Jm:, Jr~~ l!.IIUDO acids can be uSt'd for one carbon 1ource5
!il:1:11:bi:.......
aari~ o . , ~ !:l;l.UlD.acids a.re converted w Acetvl.CoA or Aectoaoctyl-Co/\
o of~gmtc azn.uw acids om w,o be- trtdiZM for glucuromc add s~nthcsls and ud ,n dd.,,,;,~
m--c
A THERAP.wnc IEffECT IN THE FOU..OWING CASE(S)
__....."-pemmshaving BCKDCK muUUIOM causmg inacUVllbOft

oÉ
. onum(PKU)
~-..t.:"" .m -Y x
_ didm dnm-~ilketonuna (P.KU} I
can be
increased

notaefinety leadtogout
decreased
www.ngygqg.gg

D affectskids
Adenosine
deaminase

retroviral
antivated
genetherapy

I enteronepaticasia
retively small no of genesforvitamin

my
X t

glycineaswell

O
 C hoo.se the one CORRECT at.a
28 lUCH ianien1.
A~

B 'Th:s«-"'---~
c~
D

E... «.::.-::
caz,..,..,. I
29 COMrotn, 'D:R

D U~a:id
E Pyn3cc:
eom trR.EA- AND ?-..'TIP~un~mm e. c-.,~;r.,a ~,
A.A......,-.; .,1

B ffi.l..;A.l..;::
C.Az.....-.:;:....
D~
E .,-.,...__,.
31 \\'HICH STATL\~ "T 6~
A ~;:;;b E scnes; It r==:::c
B p-oi~ :~
PY"'Oil: ;05zfirr
• C et ~ ; a c!... ct:oa.;.c;;-.-,.Ji l:::clSj~i:c t
D e::i r:o I ecfs• m~~c:: n:x ~S'j"::~ ;::s
E.c!::~¢w .!.
32 \\lOCHS TA -
A Tbca
B Ill tw-, ra 21 }II
........
__..,_._
C. Same o€Dt pUCt.Zoga ai. mLZIID
D Dqr•Me« 1 Otf all mrmo acids
E. TIie DIQWl:sal p:mnc code does
3.3 Vw-1DCH ENZYME CATAL
B QSr"1',,.'"fHESl~
~ - ~ ~m i~~~ Mer-"'7:fe
B- :a 11/!lt.;;ne c,:i;:'.,v
C F':ni:wsci.- deru::,vz
~o ~ P ) ~ (PRPP) rs"-c,e:.r._--rz
B. ammon mz+ AIR
34 WHICH OF THE f OUO\\<lXG STATEMn-, -S lS :sOi Olfi£CT
,A. mac.ned VLOLau urn·ilrMr t"C the
B macasec! gJuc.wc:ogWCSlS ex
C. ~-m_ prOl£ID aad k4Ee b:cies SJ::::::-.::!~l e !:w'ld
0 g.lnro9e D M-,A':111 ts dimi:tisbed CS, a€-p:q-..t:S • Gt£ .:4 g)e If
E.. die pw agc,a enec, de +wnatrs lb: I.OU.! n:.enhr&zr
~~~" 'JNE
A hymoxy\atiall requires ictzihydro fi>Z (FBI - "' C •
B 11rODMOC oag opml'I! u., u::s b.) a ~<ku.q -- .ca 7
c ate•IPMahtim r,<~ ~wn:m tit'ffl s«.. =•
D 111 1.:..1.. 001h.tiimmon m
,eo-e
me blood• MN-3 elev•~ 1
a pn:cunor far melanra Sj- 1 •
••-•tlll
 Ch oose the one CO
C T statemsm.
28
?!-iJCHS1A}EM
A Tbs e,n
S.yi:.:.:;r:rn.-.... IS 2:Sir..<Q:~

2!: C MPOU:-0,'D R
A.. GAB.:.\ fno
• B Ak:::=f ut
C.AspiG Uttl'froo ~~
D u~ acid trQ;::j l b ~ -
. _ E. I ; ~ ~ n:d bh>.1
3D BOTH l ; ~ - Ml> lrrJ'r.
AA-~ roxJDE,
B
C
Serbc
I!)
E.<:it:~ ~
31 \VHICH STATEMf.l\.'T IS.
A c::o;;:;;i~. 2 sencs i! c::::'oe=
8 w-;;y
I,) ~ 4:,3:.e
- C. c L.::a u :c:4:::r~ uf
D r:r:rc::Af'.~» c l ' ~
E. Che pn._.
~ pt1>:b1 C$ OfO
52 \\"'HJCH STA1'E.MENT~ £.
A.. Tbc C e".epm ~ a ; . _ ~
B lnh+&W4 2 ~aD)~
C.Swofd aep- og JC aumKio stas
D 111mJ0 adds ca
E. 'the annasal cock does al:it
33 VrlDCH ENZYME CATAL~"ZE.S 1'HE
OSTh"iHESJS"
A ~ ~ ~m ~~C?M :f~
a xm:h::ne
C ~de:v: n;r:s-
1 D Pft!lS\h- ibos,:i P } t ~ · (PR...~ az:½ "" •
"'.,,!'!'l:SiC
E.. -,,JnNrnidaznr AIR
34 V.lilCH OFTIIE fOLLOV.-1'.SG STA~ "1'£S IS~ OCP.1~ ,CTr~ 1iY?E.
•A. macascd '\ri..J)L 110 Cffti I iPCJIX' ICi the
8 IDCffil5Cd gt,• u.:ogwest S m Tm::
C lrpo~ pcum degad ~ man= tl'! b::o5 sr-~ ~ de,.::n:aed
D me a Jt)0rt a dorulshed a=- arl:+•)C}US e, G!.C g)fc 11
E. die gP ag,,G dfea Oi mPSMH me~ 0 abof1'1Z
~'1NE
A b\~bt al 1eqaues ~dro!o brc (fH4 • < f M
8 lfflNbC mg openng (l(X.U{S ,b y a h)am:,W .. aCL
c_ acamed•han llf lb dt,_g,amrim uam< Sa h 0
D m . . . rm<OdllD OO m die b&ood. MSC,. ,.,; I
:saft as • pecurD' fur meu•unwa S.]P as
 ..... " 'o1. ~na ··- .... ,o ~usrect.
3rd state
C. If 2nd and 4th statements are correct
D. if only the 4th ta ments are correct
E. if all statemo n~ tement Is correct.
u:a aro correct.
11 WIIICII Mt. l'AHOI ICA
l, mcthyl • l.tYACllV BCAkUO NUNllSA R.ECARlU
• En ON Tf::TRAlfVDiC.WOUTt;
Ag,,ccwh1chyt.lc
2 ITl&:thmyl
'.l , l'o,myl
•1
12 l l!P l·Ot.l.OW IN<., s I \Ir MHN res ., .
~ . I u1 m,1tlon nl pho~phonb o ,yhunlnc (~~AA~E r R~P. fOR 1llP.. DI. NOVO PURD.'E NUCL£07I DESYNTH ESIS
.... 1p d~_in"'td1ng procc,,,i,; ) 1-S nee1111vcly regulated by IMP (lrH)Slne mon~mi .te)
V6Atpneeded
oiil . l·onm,tw11 of pho-;phorib I
It nccu1s Ill 1hc C)'llhOI Oit) Amme (PRA) ls negatively regulated by AMP.
O
13 Wtll( ll Of nth FOl LOWING s·1 A'l 1.MbNTS IS (AM} 'lRUH'!
O
I . lhc ndllX>llt°\.tlll level 11\ plll!lrnll in,1ct5cly C.\JIT~lutcs WIU\ rat mll'is
2. the ud11,c,ncct11, level in plasmu increases in type II diabetesx
Bo 3. ~J)Cl'illc 1>01) u,,s,11urat~d tutty ncich (PlJl'As) c:nn increase the synthcsi5 and
I. nthpo<') tr, nl-io p1uduc~ und !.ecrctc g1ucav.oo pr
oducuon of adt
ponc<:UD
14 C,\IU\t\M O\ l l11\0St~llA n! l N Tl m l.lVfR
l . In cn_ote ot 1t,i dcvutccJ m 11ochondrial level II f?OCII into the C)'lO\ol where it m h in
O
2. ~y:nthesis .,,r Ill\~ ,,llostcric octiv11tor required for CPS-I attivuy is 'enhanced byay.;:.su

88 , Is 6) ,utws1:r.cd ~n the cy10'!0I by CP!-i-1 l thnt i~ pa.rt of a trifunctional enzyme. r

41, ls S) 11\h~~17.ctl II\ the n\lt('l(hondri11 by Cl'S-1 '"bich is activated allostericall1,
15 IN 1'11li URHA CYCLH OF lllll llVl•R:
y
I The highest degree of h) pcrummonernin is expected for the
C)C'lt'
l"rotcln nC'l, d IN induces the cxpre~ion of U1c urea cycle mzylWIII
CO
"'i

J\oth ntuag.:11 ,,r U1c u1~a 1s pr,widcd directly from asp1111111

01~ dclie1ency ls X•linkcd nnd cnuscs hypcrammoaamia llld Of01k>uOlllt
MJ TU'\ I TINP ll3'rRAIIYDROfOLATE REDUCTASB C6T1T (A22ZV)
NSI Ql liNCr(S).
I h ,s ncC'OJU?imicd b) ckvntcd uracyl incorporation inllO the DNA
2 U cnuscs megnlublas,ic nnemin
3 11 cnusc~ hype1 mclhionincml11 •
4 ll c-.amcs ft'll\h,-el) mild homOC)stc lncnna
17o \:5PAR1~A1'6 Al PHA•KlITOGLUTARATETRANSAMINASE:
l ~qulrt':S pyrido~111-,m0Sf'hatc (PLP) ns cofactor
BO 2. C!\IAl)~ rut oxidnti\l\i d~~minntion x
3 docs not dim mate lhc nitrosm from the
.
ammo
..
ac,d pool
O 4 <'.al\ be found cmt) in pao.,lwm ~ x
18 AC11\ A110N OF AMP-DliPENDE~"l· PROTEIN KINASE (AMPK)

I
I d mi.\. hn; 1 t,u,gt"ncsis

q of l.!tt\
l m-a.~ glum_~ upw.c
actd
g4 No.'i.-ms ofrnok~c.m l synth~ti
nthcs:is
glytol):-is In m)ocardtal cells r

EO
1P Lhl CJN!i:
I Acn,11re, GI UDI N shouldbe BUD
O
, lcs t~~-id dm\'3U,-e produced b) tran510'in,...
J h a.."ll cssrnn:il mmno odd g
Wr m\. st o htT ruruno nods, n as
~SEQlfE4'-;CE~ OF SEVERE VITAMIN
lmh.L"h~ D~A bypmneth) lllioD pac it.a
O -,xcte--tttinn :ntnUJ
•~ unc oc d txmtlon due
snc anm1ta
ID• X

O ..,Jl<lh
 11 ll I l
,u 1,ttV 111111,
I 1I I
,I\N!IWI if I Ill NI
I 1I I
fl, i, 1111 l tt l l 11 111 I 11 I
1111 ., .. , , ..,
'"' ,. .... 4111
11h 11111 <lllh N I 1,11 fl ,Ji 1
tt lillillltlHII II ill I I /111 11
1•111 It I 11) 11111"'"
!11!1111 t ,,t_y ,.. 111 ti ,11 q
t I ,, 1NI
ti\'N IIII 1fil1 I
111 ,.1 ll l'l nl I'
;,fl \I,
ll t 1111 1,111111
A\ tllh P• 1•
1
11 111 cll Vll lt , I 1 ' t; 1"'''
~: 1 ollll l'lult l'm11lllf 11
1

1) tlllt '1h l1

NI I I IN \\II I I I I 11 l I A 11
•
4 I
I

J
11 c II I'" I ~II I \ 11 II lfll :II I h Vd1tt li)'lt1i)'I I 11/\
ti I If 111111(111 ,,1 '"' II 111 1 . 1,,11t1lt1 h,,11,I lo•t1ttl 11 l1

,'
I I
11 1\III,,,.,, HI
1
I'"'''"'
II I lfo•II
II 11 r. h ' 11,,11 1, ,11111t·1 II 1111111111HJ
I hi I 11cJ 1111 l,luu11 h11 11111 I

,1 r ''" ,,,,,,.,c,11\ "" N1 •Nl' Hc 1111N1J( II NII \MINI I /\I •1111s1

t1 ,,,, ti i, MI NII J IN \l(I
I 11
: I 11111 111i,
I I 111111111111
if /\l jjllllll(UIII i' lllllhl
'I ""' Hl/\P.IMIIN /\NII IHIIIII\IC 1 11
I /111/ro nt lt,if") It' 11111o11 /11,111h111 111 rn lt13 /1 ca 111,l11111 p1,11lm 111111 IIJIII n11l11\:h11111h Iii ' l\1111160
: 1h1c 1,, 111, m 1 , ,I 11111 ,111,I ,,,.-1111111111
1 11 lllll N',t ll/•lu, h-1,ip./u1,11111r ,lrph 1111111111 11116 11 tho 111th,1111111h1111111,1lt11lll h)1h11HCllll'10
,1 / 11111 ,., 1l10 rlr~ ,,tr,/ /'I 1111111/111" hh•ll) 11lhc~l1
lJ IJIW A< U)
I "/lf11il11, et/ h) 1111111l11111· 11~1111so
2 111111 ~"" 1111•11 111 1hr lt/11111I Ill ltli•h 111 g11U1 p11llc11h
1 t1c111 ,-.,/ Ni! '"''"' 11pli1h 1111,, /111111 1lrp11~11, 111 1hr Jul1111
4 lo'CI 111r 1r11tCJ l1c,111r11tly III ullnCt't 11111um111 Idler 1n1l1othcrnp)' (llUtiur lyal1111ymlrome)
I~ II W I Ill AMINO A< 'II> 11/\C lo: !JONI S
/ t lie 1lt,:t1t1111 11111, uf ""'"'" 111111, ,,ro\ llfc.1 ryplonlly •hour I0• 15~ of lho roqulrc,d cncrlL)' 1n tho hunum hody lhcmg un
Wc.1lt111 tlli!I)
!#,one t•I u11b,' 10111t, kc1c,,ir11lc amino acldl can bo uNd ror one carbon IOUl'COI
bon bldho110 ofll.cu.,,icmlc amino tcfdl an convlltld IO Aoetyl-CoA or Acetolcetyl-coA
,n b.lclbollo of kor111on101111lno aclda cu alao bt udUad tor aluouranlo acid ayntbeala and used in detoxifica
llon, uf rho llvor tion
Ps1•1 CUI P(XJI> I IAS A THHRAPBtmC BPP8CT IN 1118 POLLOWINO CAIB(S)
IAu, Vil, II, co,ualnln1 dlor In aurt,uc Pll'IOlll bavlq BCXDCK IIIUlldau cauatna Inactivation of lhc kmasc
t""1ffralam, dltt In claulc phtny... ..,_ (PKU)
la dltc bl enc
dtftcfency
••,. cfMI fD 0....,C ,,,..,llulaawla (PKU)