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Lecture 01 - Introduction
Reviewed

Created @May 29, 2022 2:03 PM

Class PATH3206

Type Lecture

Incidence:
Most common cancers may not be the most dangerous

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 New Cancer Cases - Types:
Prostate cancer is the most commonly diagnosed cancer for males

Breast cancer is the most commonly diagnosed cancer for females

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 Incidence - Age:

New Cancer Cases - Sex and Age:

In 2019, males are estimated to account for 54% of new cancer cases
diagnosed

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 People aged 65 and over are estimated to account for 58% new cancer
cases diagnosed

Incidence - Trends:

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 Mortality:

Incidence vs Mortality:

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 Survival:

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 Survival - Cancer Type:
Of the top five most commonly diagnosed cancers, lung cancer has the
worst survival for both males and females

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 Survival Trends:

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 Transformation and Malignancy:
Abnormal cells arise due to mutations

Abnormal cells proliferate

Tumour may become malignant (can metastasise) by gaining contact with

blood vessels and lymph vessels

Tissue Context:
Tumour also contains fibroblasts, immune cells, endothelial cells apart from
just cancer cells

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 What Causes Cancer?
Deletion, duplication, insertion etc. of the genes may cause mutations

Genetics may cause cancer

Risk Factors:

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 Treatment:

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