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Atoms
Cellulose
Wood
Chair
Same goes for living organisms like birds, humans, mammals, etc. We
have different organs to do different tasks like breathing, tasting,
thinking and so on. These organs are a part of an organ system, like the
respiratory system, the digestive system and the nervous system. These
organs are made up of things called “tissues”. These are fibre-like, thin,
and useful structures for the body. These tissues are formed from unit
substances called cells.
Cell
Tissue
Organ
Organ system
Organism
So, what is a cell then? A cell, is a functional and structural unit of life.
My science teacher always said to me, “Traditionally, when a statement
is short and concise, we take each word seriously.” In this case, let’s
start with structural.
As seen in the above pyramid chart, we can see that a cell forms
structures to comprise an organism. This forms the structural part of the
definition.
Being a fundamental part, the cell has to play a lot of roles depending
on the situation. Let’s take the examples of the neuron and muscle. The
neuron needs to transport information across the body; hence it needs
a long and thin yet strong body. Taking the case of muscles, they need
to get the oxygen in large amounts quickly, so that the motion keeps
going. Here we can see that a cell does some work which helps the
organism in the whole. This forms the fundamental part of the
definition.
Organisms come in two types: unicellular and multicellular. Unicellular
organisms have only one cell to their name. These can range from the
tiniest bacteria to the largest algae which invades the lakes.
Multicellular organisms have many cells in their name. They can range
from nostoc to big elephants. They often have trillions of cells.
Fun fact: The human body has 724,000,000,000,000 cells.
There are three factors that determine the function of the cell:
1. Nucleus: Let’s take an example of a computer’s CPU (central
processing unit). What does a CPU do? It processes the
information and gives it as an output, and in some cases, store
the data for further usage. The nucleus is a sort of the CPU of the
cell. It controls all the activities of the cell like producing energy,
making proteins, creating DNA and RNA and so on. The size of
the nucleus depends of the space allocated to the cell and the
function. For example, the muscles cells need more energy
producing organelles (organs of the cell) than a big nucleus.
Nerve cells need prefect coordination to send information across
the body. Hence the nucleus is kept isolated from the rest of the
cell.
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“Cell structure is a little like gardening. You sit and look at the
cells and then you see something and say, “You know, that
doesn’t look right.”- Siddhartha Mukherjee
Cell- The Biological Atom: Part 2
“Life is a whim of several billion cells to be you for a while.”-
Groucho Marx
In the previous chapter we saw the different categories of cells on the basis of
different factors like complexity of nucleus (eukaryotes and prokaryotes),
number of cells (unicellular or multicellular) and so on.
But what we have never looked is how the cell works so seamlessly.
Just as we have organs to perform our vital functions like how the lungs
helps in breathing, the cell has organs known as cell organelles. Each
has its own unique properties and functions. We will we be first looking
at the organelles of a prokaryotic cell and then progressively move to
eukaryotic cells.
First up is the nucleoid. To feel prokaryotic cells better about
themselves, they have a 3rd grade copy of a true nucleus called as a
nucleoid. Apparently, it stores all the genetic information of the cell.
The nucleus has many complex things inside it. The nucleus has an
outer covering called as the nuclear envelope (sad you can’t post any
letters in it) but it is not smooth and rigid as you might think. It has
openings so to let input material come into the nucleus. Like the cell
has cytoplasm, the nucleus has its own jelly-like matrix known as
nucleoplasm. Chromatins are suspended in it. At the heart of the
nucleus is perhaps the most significant thing of it, the nucleolus. It
sends information to start the productions of protein-producing
ribosomes.
The next organelle is perhaps the most dangerous organelle of all, the
lysosome. It is known as the “suicide bag” of the cell because it dies
after doing its function which is to basically destroy the thing it is
specified to. To give a more peaceful definition, when a cell organelle
is worn out or is doing the work in a wonky sort of way, the lysosome
goes and sprays hydrolytic enzymes all over the organelle. It also acts
as the cell’s army as it kills the viruses, bacteria and other stuff which are
trying to invade the cell. The lysosomes are activated by the nucleus
and are manufactured by the Golgi apparatus. It is covered in a single
membrane of width 100 µm. If you want to infiltrate the cell,
manipulating the lysosome is your best bet.
Image 32: The lysosome, the most dangerous and
unstable organelle of a cell.
Image Courtesy: dreamstime.com
The next organelle is the vacuole, the storehouse of the cell. It stores
important nutrients like proteins, complex molecules, ATP etc. for the
cell for later usage. Animal cells have many vacuoles but are small in
size, whereas in plant cells, the vacuole is the prominent organelle after
the nucleus. It is covered by a membrane known as the tonoplast.
Following is a diagram of the plant cell’s vacuole (diagram won’t vary
much in animal cells, but will be a lot smaller):
Image 33: The vacuole is one of those organelles which
define the similarities between a plant cell and an
animal cell.
Image Courtesy: shutterstock.com
The next organelle is the centriole, which helps the cell in cell division.
Cell division is a fancy way of saying that the cell splits itself into two
parts called as daughter cells and then those daughter cells divide to
form two more daughter cells and so on. They are only two for each cell
and position themselves at the poles of the cell. The function of
centrioles is to help organize the chromosomes before cell division
occurs so that each daughter cell has the correct number of
chromosomes after the cell divides. Centrioles are found only in animal
cells, and are located near the nucleus. They are made of a protein
called as tubulin.
Image 34: The centriole, the helper of cell divison.
Image Courtesy: science.howstuffworks.com
Image 35: The cell wall, the plant cell’s toughest bodyguard ever.
Image Courtesy: thoughtco.com
The next organelle of the plant cell is the plastids. They are the next
version of the mitochondria, only more powerful and versatile. They do
complex stuff for the cell like manufacturing carbohydrates, proteins
and fats, giving the green colour to the plant and much more. They
also do the most famous thing which plants are famous for: making
food out of thin sunlight and air. The plastid is differentiated on the
basis of function they do:
1. Proplastid: A proplastid is an organelle found in the
meristematic regions of the plant. It is colourless and small. It is
from where plastids are derived. It is still undeveloped and may
divide to produce more proplastids. As the cell containing
proplastids mature, the proplastids transform and develop into
plastids with specialized functions.
So…I think we are done with all the basic organelles of both
prokaryotic and eukaryotic cells. Note that in some cells, they have
transformed their organelles to suit their needs. This is called
adaptability of organisms. For example, amoeba has modified its
plasma membrane to pseudopodium (meaning false feet). It helps the
organism to engulf the food on its way.
Let’s now proceed to the second ladder of our biology pyramid-
tissues.
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• Collenchyma: The cells of this tissue have thin walls that are
especially thick at their corners due to deposition of cellulose and
pectin. Intercellular spaces are generally absent. Collenchyma
provides mechanical support for plants with no secondary
growth. It is present at the margin of leaves and resist the tearing
effect of the wind.
Next up is the cortex, the second-outer layer of a plant. The cells are
mostly thinly-walled parenchyma and may contain chloroplasts in it (the
outer cortex). It lies below the epidermis and forms a part of the cork of
obtained from a woody plant. (Refer cross-section for diagram.)
The last tissue of the plant cell is the epidermis. “Epidermis” is a general
term meaning “outer layer”. It is the final covering of leaves, roots,
stems and flowers of the plant. It protects against water loss,
regulate gas exchange, secretes metabolic compounds, and (especially
in roots) absorbs water and mineral nutrients.
(Refer cross-section for diagram.)
We have now finished with the plant part of the tissues. Let’s move on
to the tissues present in our body, the animal tissues.
Animal tissues are classified on what do they do, where they are
present, why they are present and so on. Broadly, animal tissues are
divided into four types: epithelial tissues, muscular tissues, connective
tissues and nervous tissues.
Starting off with the epithelial tissues, whose main function is to cover
and protect the sensitive organs of the animal body, basically what we
call the skin and the dermal section. They also form ducts and glands,
like the sweat glands on our skin. Epithelial tissues are classified on the
basis of shape, i.e., the shape of the cells.
• Simple epithelium:
a) Simple squamous epithelium: The cells of this epithelium are
thin, flat, irregular in shape with no intercellular space. They
protect the linings of important organs like mouth,
oesophagus, nose, blood vessels etc. Skin is also composed of
this epithelium.
• Complex epithelium:
a) Transitional epithelium: Transitional epithelium is a stacked or
stratified epithelium in which the shape of the surface cell
changes depending upon the degree of stretch. When the
epithelium is not stretched, the cells of the surface layers are
large and rounded.
Image 52: A diagram of the transitional epithelium.
Image Courtesy: microbenotes.com
Next up, we meet the muscular tissues. They contain cells with strong
contractile ability which produces movement in a body. Muscle cells
are long and slender, arranged in a parallel pattern. These cells have a
lot of microfilaments (a part of the cytoskeleton) which are composed
of actin and myosin (a kind of complex protein). The muscular tissue
can be divided into three parts:
a) Skeletal muscles: Don’t get fooled by the term “skeletal”. It means
that these muscles cooperate with bones to produce voluntary
(stuff which we can control) movement. Some good examples of
voluntary movement are running, twisting your abdomen, typing
a letter to your grandmother etc. The cells of the skeletal tissue
are cylindrical with many nuclei (plural for nucleus) arranged in
bundles. It is present in the locomotory reigons of the body, like
the legs and the arms, also in the pharynx, tongue (yes sir, tongue
is also a muscle) and at the beginning of the oeseophagus.
Image 52: A microscopic image of the skeletal tissue. You can see little
bands across the tissue and some purple dots. The bands are called
striations and the purple dots are the nuclei. Fun fact: Skeletal muscles
are also called straited muscles because of these striations.
Image Courtesy: teaching.ncl.ac.uk
a) Smooth muscles: Smooth muscle cells are spindle shaped and
has a single nucleus at the centre of each cell. These are also
called unstraited muscles because they don’t have any bands
across the tissue. These tissues are mainly found in areas of
involuntary (stuff we can’t control) motion, like at the intestine,
arteries and veins, iris of the eye, ciliary bodies, uterus, urinary
bladder etc.
Image 54: A microscopic image of the cardiac muscle. You can see the
branched tissues containing the bands and a single nucleus for each
cell.
Image Courtesy: en.wikipedia.org
Image 56: A microscopic image of the dense connective tissue. You can
see the dense packing of the cells, hence the name, “dense” connective
tissues.
Image Courtesy: en.wikipedia.org
Image 62: A detailed diagram of a nerve cell along with the cyton,
nodes and the dendrites.
Image Courtesy: thoughtco.com
So, we are done with all the major types of tissues known to mankind.
Let’s move two steps down (ignoring the organ systems because the
book would be too detailed), the organisms themselves.
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The next thing which came to the biologists’ mind was that how to
differentiate two varieties of the same thing. For example, a rose is
typically red in colour with some spiky thorns around its stem. There are
many other roses, like the Dog-rose, Multiflora rose, French Rose and
so on. To differentiate between all these similar-looking yet different
species, we have come with a particular nomenclature. Remember we
used to define new covalent compounds in the chapters “Carbon’s
Army of Compounds-1” and “Carbon’s Army of Compounds- 2” on the
basis of number of carbon atoms, functional groups, type of bond and
so on. The art of naming stuff on the basis of some rules is called
nomenclature.
Coming back to the biologists, they needed a system to differentiate
between the local varieties and the real varieties. Our good man,
Carolus Linnaeus, came up with a simple system. In this system, each
organism is provided with two words, a generic name and the specific
name. So, if I wanted to differentiate between a jaguar and a leopard, I
can simply write their common genus, which is, Panthera (a genus of
nasty, big cats) and combine it with their specific names, pardus for
leopard and onca for jaguar. Combining these two, we get the
leopard’s name as Panthera pardus and the jaguar’s name as Panthera
onca. Note that both the generic and specific names are usually Latin
and the generic name starts with a capital letter and the specific name
follows the generic name, starting from a small letter. This system,
proposed by dear Linnaeus, is called taxonomy.
Another key thing in bio-diversity is the hierarchy of taxonomy. It is a
system of classification in which taxonomic categories are placed in
order of a logical sequence. The sequence is as follows:
Kingdom
Phlyum
Class
Order
Family
Genus
Species
Image 65: The family Ursidae contains bears and the distantly-related
giant panda.
Image Courtesy: en.wikipedia.org
• Order: A number of families having some common factors, are
grouped as in an order. The family Ursidae comes under the
order Carnivora, which stands for carnivorous animals. (Note:
Even though most bears are omnivorous, we consider most
omnivorous animals in the order Carnivora.)
Now let’s move to the main details of each kingdom roughly because it
will take ages for me to describe the whole kingdom, which also
includes its families, orders, classes, phylum, genera, species and the
whole taxonomic classification of the kingdom.
Let’s start with the most basic kingdom, Monera. As we discussed
earlier, the kingdom Monera contains unicellular prokaryotic organisms
like bacteria, archaebacteria, cyanobacteria, mycoplasma and so on. It
is said that they were the first signs of life to originate life on Earth and
have not changed much since then. Some organisms in Monera have a
cell wall made up of a complex molecule called as peptidoglycan. They
have a lack of proper cell organelles, that is, they are mostly prokaryotic
in nature. Organisms like blue-green algae can synthesise food from
the sun while others depend on other organisms, that is they are
heterotrophic in nature.
So we are done with all the factors for life to exist. We went through
galaxies, compounds, cell organelles, the early solar system,
humongous stars, tissues and finally organisms, which obviously
includes us humans. But what do these factors mean when we cannot
co-relate them with other?
It’s time…to connect the dots.
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