H-MOLE/GESTATIONAL TROPHOBLASTIC DISEASE No FHR or palpation of fetal parts
S/Sx of preeclampsia before usual time of onset such as
(HYDATIDIFORM OR H-MOLE)/MOLAR PREGNANCY elevated BP edema and proteinuria Abnormal proliferation and degeneration of the High level of HCG with excessive N/V before 20th week of trophoblastic villi. gestation As the cell degenerate, they become filled with fluid and Anemia often accompanies bleeding appears grapelike vesicles per vagina with soft abdomen Maybe bright red and Dark red to brownish vaginal and absent fetal parts on palpation bleeding with 12 weeks Ultrasound showing a characteristic snowstorm pattern. Two Distinct types: 1. Complete molar pregnancy THERAPEUTIC MANAGEMENT: • Have only placental parts, forms when a sperm fertilizes an 1. Suction Curettage or dilatation and curettage to remove empty egg mole • The chromosome are either 46XX or 46XY but are 2. Serum hCG monitoring − HCG should be monitored for contributed by only one parent and the chromosome material 1 year and should be negative 2−8 weeks after removal of is duplicated. mole. It is monitored every 2 weeks until normal then • It usually leads to carcinoma monthly for 6 months then every 2 months for the next 6 2. Partial Mole months. • It has 69 chromosome in which there are three 3. Chest x ray may also be done every 3 months for 6 chromosomes for every pair instead of two. 23 from the months because H− mole cancer cells can metastasize to mother and 2 sets from the father. This could occur when two lungs. cells fertilize one egg. 4. Oral Contraceptive use for 1 year− the woman is • It rarely leads to carcinoma advised not to get pregnant yet and pills should not contain estrogen Risk factors: 5. Methotrexate − anti cancer drug for one year to prevent 1. Higher occurrence in asian development of malignancy 2. Women below 18 and above 40 years old 6. Hysterectomy 3. Women with low socioeconomic status who have low protein intake NURSING CARE: 4. History of molar pregnancy Health education about contraceptives and rusks of future pregnancies; pregnancy is delayed for at least 1 year. ASSESSMENT: Updated laboratory examinations to detect rising of HCG Size of uterus is disproportionate to length of pregnancy levels UTZ shows no fetal skeleton /parts Assess V/S, I/O Provide emotional support