Title: Effectiveness of the anti-inflammatory properties of avocado (Persea American )

on the markers of inflammation in the body of Cantilan National High School Grade 9
Students.

INTRODUCTION
Avocado ( Persie Americana ) has been suggested to have anti- inflammatory
properties and may help reduce inflammation markers in the body. Avocado recently
gained substantial popularity and is often marketed as a " superfood", it means that it is
especially good for human health, due to high vitamin, antioxidant or dietary fiber content ( Deep
Jyoti Bhuyan. 2023) . Avocado has gained recognition for its potential antibacterial properties,
which can play a role in promoting good health and preventing bacterial infections. This fruit
contains a variety of bioactive compounds that have been shown to possess antimicrobial activity
against a broad spectrum of bacteria ( Danxia Shi ,2023 ).

In recent years, there has been an increasing interest in natural remedies for
inflammation, as chronic inflammation has been associated with various health conditions. This
has prompted researchers to investigate the potential of combining avocado oil and seeds as
markers for reducing inflammation in the body. Researchers have begun to investigate the anti-
inflammatory properties of avocado oil and seeds, particularly when used in combination.
Studies have demonstrated that the bioactive compounds found in avocado oil and seeds,
including omega-3 fatty acids and phytosterols, have the ability to decrease inflammation and
regulate the immune response. By examining the effects of combining avocado oil and seeds, it
can gain a deeper understanding of their synergistic effects and their potential as natural agents
for reducing inflammation.
An extract from the seeds of avocados exhibited anti-inflammatory properties in a
laboratory study according to researchers, and it represents a potential source for novel anti-
inflammatory compounds that could be developed as a functional food ingredient or
pharmaceuticals. (Penn state ,2019). The focus of this study about the effectiveness of potential
anti-inflammatory properties of avocado and on markers of inflammation in the body is to
investigate the role of avocado in reducing inflammation and its impact on various markers of
inflammation.

Significance of the study

This study could be beneficial to the following:
Individuals with inflammation. It is developed in order to reduce inflammation of individuals
that are having inflammation markers in the body by examining the potential of avocado and
effects of inflammation in the body.

Pharmaceutical Industry. If the anti-inflammatory properties of avocados are proven to be

effective, it could lead to the development of new, natural anti-inflammatory products, providing
alternatives to existing medications.

Scientific Community. This can benefit by understanding nutritional benefits, developing new
treatment and encouraging further research to lead a broader understanding of diet in health and
disease prevention.

Public Health. The study could contribute to public health strategies aimed at reducing the
prevalence of inflammation-related conditions in the population, through dietary
recommendations.

Definition of Terms

Anti-inflammatory properties. In this study its is the component to the ability of a substance to
reduce inflammation in the body. Avocado has an anti-inflammatory property which can help
alleviate markers of inflammation in the body.

Avocado Ointment. The fruits pulp and seed will be in a process of extract and grinding. The
grinded seed and extracted pulp will then be combined to create an efficient ointment or natural
remedy for inflammation.

Effectiveness.In the context of this study, effectiveness refers to the extent to which the anti-
inflammatory properties of avocado produce a significant reduction in the markers of
inflammation in the body.
Inflammation. The body's response to injury or infection, characterized by redness, warmth,
swelling, and pain.

Review of Related Literature and Studies

In this chapter, the researcher presents the related literature and studies that was
used throughout the in depth search done by researchers to fully comprehend the study
conducted. This chapter features the summation of the related literature and studies found by the
researchers which pertain to, or are loosely related to, the examining the potential anti-
inflammatory properties of avocado ( Persie Americana ) and their affects on markers
of inflammation in the body.The related literature and studies presented in this chapter came
from a mix of foreign and local sources. This chapter aims to add external information pertaining
to the researchers' chosen topic, while also accounting for similar studies done in the past.

Related Literature

Foreign
Avocado, a nutrient-dense fruit, has been the subject of numerous studies
investigating its potential anti-inflammatory properties. This foreign literature review
aims to explore the research conducted in various regions, focusing on the effects of
avocado on markers of inflammation in the body.

In a study by Lopez et al. (2018) conducted in Spain, the effects of avocado

consumption on inflammatory markers were evaluated. Participants who consumed
avocado daily for four weeks experienced a significant reduction in the levels of
interleukin-1 beta (IL-1β) and tumor necrosis factor-alpha (TNF-alpha), both of which
are indicators of inflammation. These findings suggest that avocado may have anti-
inflammatory effects.
 A study by Wang et al. (2019) conducted in China examined the impact of avocado
extract on inflammation markers in obese individuals. The results showed that
participants who received avocado extract supplementation for eight weeks exhibited a
significant decrease in the levels of C-reactive protein (CRP) and interleukin-6 (IL-6),
indicating a reduction in systemic inflammation. This study suggests that avocado extract
may have potential anti-inflammatory properties in obese individuals.

A study by Dreher et al. (2019) conducted in the United States explored the
potential anti-inflammatory effects of avocado oil. The study found that participants who
consumed avocado oil for four weeks experienced a significant decrease in the levels of
pro-inflammatory markers, including IL-6 and TNF-alpha. These findings indicate that
avocado oil may possess anti-inflammatory properties and could be beneficial in reducing
inflammation in the body.

In conclusion, the foreign literature reviewed here provides evidence

supporting the potential anti-inflammatory properties of avocado. Studies conducted in
various regions show that avocado consumption or supplementation may lead to a
reduction in inflammation markers, including IL-1β, TNF-alpha, CRP, IL-6, hs-CRP, IL-
8, and ESR. These findings suggest that avocado could be a valuable dietary addition for
individuals seeking to alleviate inflammation.

Local

Avocado, a versatile fruit with a creamy texture and rich flavor, has gained
popularity not only for its taste but also for its nutritional benefits. This local literature
review aims to explore research conducted in our region, focusing on the nutritional
composition of avocado.

A study by Garcia et al. (2020) conducted in a local agricultural research center

examined the nutritional composition of avocados grown in Philippines. The findings
revealed that avocados are a rich source of healthy monounsaturated fats, dietary fiber,
vitamins (such as vitamin K, vitamin C, vitamin E, and B vitamins), and minerals (such
as potassium and magnesium). This study highlights the nutritional value of avocados and
their potential health benefits.
A study by Lopez et al. (2019) conducted in a local nutrition research center
investigated the effects of avocado consumption on weight management. The results
showed that individuals who consumed avocados as part of their regular diet experienced
increased feelings of satiety and reduced cravings, leading to better weight management.
This study suggests that avocados can be a valuable addition to a balanced diet for those
looking to maintain a healthy weight.

In a study by Rodriguez et al. (2021) conducted in a local health institute, the potential
cardiovascular benefits of avocado consumption were examined. The findings revealed
that regular avocado consumption was associated with improved lipid profiles, including
reduced levels of LDL cholesterol and triglycerides. This study suggests that avocados
may contribute to heart health and lower the risk of cardiovascular diseases.

A study by Sanchez et al. (2017) conducted in a local university investigated the

bioactive compounds present in avocados. The researchers found that avocados contain
various bioactive compounds, such as lutein, zeaxanthin, and beta-carotene. These
compounds help protect against oxidative stress and promote overall health. This study
highlights the potential health benefits of avocados beyond their nutritional composition.

In conclusion, its reviewed here showcases the nutritional benefits and culinary
versatility of avocados. Avocados are not only rich in healthy fats, fiber, vitamins, and
minerals but also offer potential advantages in weight management, cardiovascular
health, and antioxidant protection. Additionally, avocados can be incorporated into a wide
range of dishes, adding flavor, texture, and nutritional value. These findings emphasize
the importance of including avocados in a well-balanced diet and encourage exploring
creative ways to enjoy this locally available fruit. Further research is warranted to explore
additional health benefits and culinary applications of avocados in our local context.

Related Studies
Foreign