1.

[1 mark]

What is found in insulin molecules?

A. Phosphates

B. Nucleotides

C. Peptide bonds

D. Glycerol

2. [1 mark]

Which statement correctly describes genome and proteome?

A. Only the genome but not the proteome can be analysed using gel electrophoresis.

B. The genome and the proteome are the same in all tissues in an organism.

C. In cells of different tissues, the genome is the same while the proteome varies.

D. Only mutations in the proteome but not in the genome cause any variability.

3. [1 mark]

Which protein has the highest tensile strength (ability to resist breaking when stretched)?

A. Cellulose

B. Actin

C. Spider silk

D. Albumin

4. [1 mark]

Which description matches the protein?

1
5. [1 mark]

Which molecule could be hydrolysed into amino acids?

6. [1 mark]

2
 How does the proteome of a species contain a larger number of proteins than genes that code for these
proteins?

A. Some proteins have more than one polypeptide chain.

B. There are genes that code for several proteins.

C. Not all proteins are coded for by the genome.

D. Some proteins are coded for by other proteins.

7. [1 mark]

The most abundant structural protein in the human body is found in ligaments and skin. What is the
name of this protein?

A. Collagen

B. Hemoglobin

C. Myoglobin

D. Immunoglobulin

9. [1 mark]

Which is an effect of protein denaturation?

A. The order of amino acids is changed when the protein overheats.

B. The bonds between amino acids are broken by condensation.
C. Parts of the protein become linked together by hydrolysis.
D. The three-dimensional structure of the protein is altered.

12. [3 marks]

Draw a molecular diagram of an amino acid to show its general structure.

3
13. [5 marks]

Outline the production of a dipeptide by a condensation reaction, showing the structure of a

generalized dipeptide.

4
14. [3 marks]

Other than acting as catalysts state three functions of proteins, giving an example of each.

15a. [1 mark]

Keratin is a protein found in hair, nails, wool, horns and feathers. The graphs show the relative
keratinase activity obtained in experiments into keratin digestion at different pH values and different
temperatures.

Determine the optimum pH and temperature of keratinase.

5
15b. [2 marks]

Suggest two changes occurring in the reaction vessel that could be used to indicate keratinase activity.

15c. [2 marks]

State two conditions that should be kept constant in both experiments.