Advanced Practice in Endocrinology

Nursing Sofia Llahana

Visit to download the full and correct content document:
https://textbookfull.com/product/advanced-practice-in-endocrinology-nursing-sofia-llah
ana/
More products digital (pdf, epub, mobi) instant
download maybe you interests ...

Advanced Practice Nursing Procedures Margaret R. Colyar

https://textbookfull.com/product/advanced-practice-nursing-
procedures-margaret-r-colyar/

Advanced Practice and Leadership in Radiology Nursing

Kathleen A. Gross

https://textbookfull.com/product/advanced-practice-and-
leadership-in-radiology-nursing-kathleen-a-gross/

Advanced Practice Palliative Nursing 1st Edition

Constance Dahlin

https://textbookfull.com/product/advanced-practice-palliative-
nursing-1st-edition-constance-dahlin/

Advanced Practice in Healthcare: dynamic developments

in nursing and allied health professions Paula Mcgee

https://textbookfull.com/product/advanced-practice-in-healthcare-
dynamic-developments-in-nursing-and-allied-health-professions-
paula-mcgee/
Strategic Planning for Advanced Nursing Practice 1st
Edition Madrean Schober (Auth.)

https://textbookfull.com/product/strategic-planning-for-advanced-
nursing-practice-1st-edition-madrean-schober-auth/

Population based nursing concepts and competencies for

advanced practice 2nd Edition Ann L. Curley Phd Rn

https://textbookfull.com/product/population-based-nursing-
concepts-and-competencies-for-advanced-practice-2nd-edition-ann-
l-curley-phd-rn/

Advanced practice nursing roles : core concepts for

professional development 6th Edition Kathryn A. Blair
Phd Fnp Faanp

https://textbookfull.com/product/advanced-practice-nursing-roles-
core-concepts-for-professional-development-6th-edition-kathryn-a-
blair-phd-fnp-faanp/

Management of Adult Glioma in Nursing Practice Ingela

Oberg

https://textbookfull.com/product/management-of-adult-glioma-in-
nursing-practice-ingela-oberg/

Statistics for Evidence-Based Practice in Nursing 3rd

Edition Myoungjin Kim

https://textbookfull.com/product/statistics-for-evidence-based-
practice-in-nursing-3rd-edition-myoungjin-kim/
Under the auspices of the European Society of Endocrinology

Advanced Practice
in Endocrinology
Nursing
Sofia Llahana
Cecilia Follin
Christine Yedinak
Ashley Grossman
Editors
With Paediatric Editors
Kate Davies and Margaret F. Keil

123
Advanced Practice in Endocrinology
Nursing
Sofia Llahana · Cecilia Follin
Christine Yedinak · Ashley Grossman
Editors

Advanced Practice in
Endocrinology Nursing
With Paediatric Editors Kate Davies
and Margaret F. Keil
Editors
Sofia Llahana Cecilia Follin
School of Health Sciences, City Department of Oncology
University of London Skåne University Hospital
London Lund
UK Sweden

Christine Yedinak Ashley Grossman

Northwest Pituitary Center Churchill Hospital
Oregon Health and Sciences University University of Oxford
Portland, OR Oxford
USA UK

ISBN 978-3-319-99815-2    ISBN 978-3-319-99817-6 (eBook)

https://doi.org/10.1007/978-3-319-99817-6

Library of Congress Control Number: 2018968596

© Springer Nature Switzerland AG 2019

This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or
part of the material is concerned, specifically the rights of translation, reprinting, reuse of
illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way,
and transmission or information storage and retrieval, electronic adaptation, computer software,
or by similar or dissimilar methodology now known or hereafter developed.
The use of general descriptive names, registered names, trademarks, service marks, etc. in this
publication does not imply, even in the absence of a specific statement, that such names are
exempt from the relevant protective laws and regulations and therefore free for general use.
The publisher, the authors, and the editors are safe to assume that the advice and information in
this book are believed to be true and accurate at the date of publication. Neither the publisher nor
the authors or the editors give a warranty, express or implied, with respect to the material
contained herein or for any errors or omissions that may have been made. The publisher remains
neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This Springer imprint is published by the registered company Springer Nature Switzerland AG
The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Sofia Llahana
Dedicated to my daughter Elise-Katerina, my husband Richard,
and my parents and role models Eirini and Vasilis

Cecilia Follin
Dedicated to Anders, Jesper and Alexander

Christine Yedinak
Dedicated to my husband and cheerleader Marty

Ashley Grossman
Dedicated to my daughters: Emily, Sophie, Annabel, Camilla,
Cordelia, and Elizabeth
Foreword

Endocrinology nursing is a fast-developing specialty with nurses performing

advanced roles and expanding their practice to cover key roles in the future
multidisciplinary centres of excellence like the PTCOE (Pituitary Tumor
Centers of Excellence). This book has the merit of providing a comprehen-
sive guide for nurses practising in all areas of endocrinology including bone
metabolic diseases, obesity, and lipid disorders. Particularly interesting and
modern are the chapters devoted to endocrine emergencies and endocrine
abnormalities consequent to cancer treatment. Moreover, the book is suitable
for nurses serving in both paediatric and adult endocrine units and at any level
of expertise.
The book has been written by an international team of eminent nurses,
physicians, surgeons, psychologists, and other healthcare professionals,
which makes this book a valuable resource not only for nurses but also for
other members of any multidisciplinary team. Patient advocacy groups have
also contributed to most chapters with case studies and examples of collab-
orative working with healthcare professionals to improve patient care.
This is the first book ever published specifically for nurses working in
endocrinology, but it is also an excellent resource for nurses working in other
specialties such as internal medicine, gynaecology, urology, and rheumatol-
ogy due to the wide range of topics covered in the book from fertility to
osteoporosis and erectile dysfunction. Specialty trainees, general practitio-
ners, students, psychologists, and expert patients wanting in-depth informa-
tion will also find this book a useful resource.
The editors have led the way in advancing nursing practice, and this book
is a reflection of their dedication to developing a solid doctrinal body for the
discipline of endocrine nursing worldwide.

Andrea
Milan, Italy Giustina

vii
Preface

We are extremely pleased and proud that our ambitious idea to write the first
ever published book for endocrine nurses has finally come to fruition. We
wanted this to be a useful resource for endocrine nurses across the globe
working at different settings and levels of practice, from novice to expert and
from bedside nursing to advanced practice nursing running independent
nurse-led services. We recognised that this would be a challenging project to
undertake, especially as the endocrinology nursing role varies significantly
from country to country. We were, however, overwhelmed by the interest we
received from colleagues who wanted to contribute to this book, echoing the
great need for such a resource and especially from physicians and other
healthcare professionals who recognise the endocrine nurse as a vital member
of the multidisciplinary team.
The European Society of Endocrinology (ESE) formed our initial working
hub and supported this textbook from its inception. We created a strong col-
laborative European and international network; 118 eminent authors from 15
countries contributed to this book. Most of our authors are nurses, but physi-
cians, surgeons, psychologists, dieticians and geneticists have also contrib-
uted, emphasising the multidisciplinary focus of this book.
Built on the growing body of knowledge, expertise and the expanding
nature of advanced practice in endocrinology nursing, this book provides a
comprehensive resource to support nurses to develop their competence at dif-
ferent levels of their career. The authors in each chapter have done a tremen-
dous job presenting a comprehensive review of anatomy, pathophysiology,
diagnosis and treatment of different endocrine conditions supported by the
latest evidence and clinical guidelines. Patient stories, case studies and good
clinical practice examples are included to illustrate the impact of endocrine
conditions on patients and their families, to stimulate the readers’ critical
thinking and reflection and to make information in this book applicable to
their clinical practice. Many patient advocacy groups have contributed with
case studies and educational resources, supporting the emphasis this book
places on user involvement and shared decision-making in patient care.
Comprising of 13 parts and a total of 69 chapters, this book is a compre-
hensive resource for paediatric and adult nurses working in endocrinology
but should also be useful for specialty trainees, general practitioners, students
and expert patients. It also covers endocrine-related topics within other spe-
cialties such as fertility, osteoporosis, oncology, urology, gynaecology, obe-
sity and metabolic disorders. Each part covers conditions within a specific

ix
x Preface

endocrine gland (pituitary, adrenal, thyroid, parathyroid and bone disorders

and male and female reproduction) and other relevant endocrine conditions
such as late effects of cancer treatment, neuroendocrine tumours, endocrine
emergencies, obesity and metabolic disorders. There are two paediatric-spe-
cific parts (11 chapters); paediatric aspects have also been incorporated in
many other chapters, where relevant. The final part focuses on advanced prac-
tice nursing (APN) presenting an overview of role development, definition
and components of APN, including research, with many useful resources to
support career progression within endocrinology nursing. The work by our
part editors has been vital as they invited authors and coordinated and edited
the chapters in each part; we could not have completed this book without
their amazing contribution. We hope and trust this book will assist and advise
all our colleagues to ensure the best possible patient care.

London, UK Sofia Llahana

Lund, Sweden Cecilia Follin
Portland, OR, USA Christine Yedinak
Oxford, UK Ashley Grossman
Acknowledgements

This book is a testament of a successful global collaboration of healthcare

professionals, learned societies and patient advocacy groups, and it would not
have been possible without the great effort that everyone put into this
project.
We express our deep gratitude to our 118 authors who contributed to this
book; this was an international multidisciplinary collaboration of nurses,
physicians, surgeons, psychologists, geneticists, dieticians and nurse aca-
demics from 15 different countries. This book covers adult and paediatric
topics; we are indebted to Kate Davies (UK) and Margaret Keil (USA) for
editing the paediatric parts and for inviting and supporting authors who con-
tributed with paediatric aspects to many other chapters where relevant in the
book. Our gratitude also goes to our part editors who invited contributing
authors and edited the chapters in each part: Judith van Eck (the Netherlands),
Violet Fazal-Sanderson (UK), Gerard Conway (UK), Andrew Dwyer
(Switzerland/USA), Ann Robinson (Australia), Philip Yeoh (UK), Anne
Marland (UK) and Michael Tadman (UK). Their names are listed in the
respective textbook parts.
The textbook was initiated and developed under the auspices of the
European Society of Endocrinology (ESE) and has its full endorsement. We
are very grateful to Professor AJ van der Lely, ESE President (2015–2019);
Helen Gregson, ESE Chief Executive Officer; Professor Jérôme Bertherat,
Chair of ESE Clinical Committee; members of the ESE Executive Committee;
and, in particular, Professor Andrea Giustina, incoming ESE President
(2019), who has supported this textbook since its inception in 2015.
Special thanks go to Professor Philippe Bouchard, past President of the
ESE, and Professors Pia Burman and Richard Ross, past members of the ESE
Executive Committee. Their support was instrumental in developing and
establishing the ESE Nurses Committee, through which we met and worked
together on this book and on other European and international projects.

xi
xii Acknowledgements

We are also grateful to the following Nursing Organisations for their sup-
port and for approving this textbook as a valuable resource for endocrine
nurses:
• The Federation of International Nurses in Endocrinology (FINE)
• The Endocrine Nurses Society (ENS)—USA
• The Endocrine Nurses’ Society of Australia (ENSA)—Australasia
• The Pediatric Endocrinology Nursing Society (PENS)—USA, Canada
Representatives from many Patient Advocacy Groups across the globe
contributed with case studies and educational resources; we are very grateful
and have acknowledged their input in each respective chapter. We would also
like to express our gratitude to patients and their families who shared their
stories to help our readers understand the impact of endocrine conditions. We
all learn so much from our patients and are grateful for the opportunity to be
a part of their lives and to support them throughout different stages of living
with their condition.
Very special thanks go to Nathalie L’Horset-Poulain, our Senior Publishing
Editor, for her amazing guidance throughout this project. We have been very
privileged to work with Nathalie and would not have been able to complete
this book without her outstanding support. Special thanks also go to Marie-
Elia Come-Garry (Associate Editor), Sushil Kumar Sharma (Project
Coordinator), Vishal Anand (Project Manager) and all the other members of
the Springer Nature Team for their support.
Finally, we would like to express our sincere gratitude to our families, but
also the families of all of our authors, for their patience and support during
the past 3 years. We sacrificed many weekends and evenings to produce this
book and would not have been able to complete it without their unlimited and
unconditional support and encouragement.

Sofia Llahana
Cecilia Follin
Christine Yedinak
Ashley Grossman
Contents

Part I Growth and Development

Kate Davies and Margaret F. Keil

1 The Importance of Auxology for Growth Assessment����������������    3

Terri H. Lipman and Megan K. Lessig
2 Short Stature, Growth Hormone Deficiency,
and Primary IGF-1 Deficiency�����������������������������������������������������   13
Bin Moore, Amanda Whitehead, and Kate Davies
3 Disorders of Sex Development (DSD)������������������������������������������   39
Kate Davies
4 Puberty: Normal, Delayed, and Precocious��������������������������������   63
Eileen Pyra and Wendy Schwarz
5 Treatment Issues in the Care of Pediatric Patients
with Endocrine Conditions�����������������������������������������������������������   85
Peggy Kalancha, Nicole Kirouac, and Eileen Pyra
6 Transition from Paediatric to Adult Services������������������������������ 101
Susie Aldiss

Part II Endocrine Disorders and Genetics in Childhood

Kate Davies and Margaret F. Keil

7 Genetics and Family History�������������������������������������������������������� 121

Kelly Mullholand Behm
8 Congenital Hyperinsulinism (CHI)���������������������������������������������� 163
Claire Gilbert, Kate Morgan, Louise Doodson,
and Khalid Hussain
9 Genetic Syndromes Presenting in Childhood Affecting
Hypothalamic Function ���������������������������������������������������������������� 179
Kathryn Clark
10 Genetic Syndromes Presenting in Childhood Affecting
Gonadotropin Function ���������������������������������������������������������������� 195
Sharron Close, Ana Claudia Latronico,
and Marina Cunha-Silva

xiii
xiv Contents

11 McCune–Albright Syndrome�������������������������������������������������������� 207

Beth Brillante and Lori Guthrie

Part III Hypothalamus and Pituitary

Christine Yedinak and Judith P. van Eck

12 Anatomy and Physiology of the Hypothalamic-Piuitary

Axis�������������������������������������������������������������������������������������������������� 231
Kathryn Evans Kreider
13 Metabolic Effects of Hypothalamic Dysfunction������������������������ 245
Cecilia Follin
14 Sella and Suprasellar Brain Tumours and
Infiltrarive Disorders Affecting the HPA-Axis���������������������������� 255
Christine Yedinak
15 Dynamic Investigations and Diagnostic Testing�������������������������� 277
Christine Yedinak and Kate Davies
16 Diagnostic Imaging������������������������������������������������������������������������ 305
Christine Yedinak
17 Non-functioning Pituitary Adenomas������������������������������������������ 321
Judith P. van Eck and Sebastian J. C. M. M. Neggers
18 Thyroid Stimulating Hormone Secreting Adenoma
(TSHoma)���������������������������������������������������������������������������������������� 335
Christine Yedinak
19 Prolactin Producing Adenomas: Prolactinomas
and Hyperprolactinemia���������������������������������������������������������������� 343
Christine Yedinak
20 Growth Hormone Producing Adenomas: Acromegaly�������������� 365
Karen J. P. Liebert, Daphne T. Adelman, Elisabeth Rutten,
and Christine Yedinak
21 ACTH Producing Adenomas: Cushing’s Disease������������������������ 395
Raven McGlotten
22 Pituitary Surgery �������������������������������������������������������������������������� 415
Jürgen Honegger
23 Pituitary Surgery: Nursing Implications ������������������������������������ 433
Sarah Benzo and Christina Hayes
24 Radiotherapy���������������������������������������������������������������������������������� 447
Ahmed Al Sajwani and Mark Sherlock
25 Hypopituitarism and Growth Hormone Deficiency
in Adults������������������������������������������������������������������������������������������ 469
Sofia Llahana, Anne Marland, Mila Pantovic,
and Vera Popovic
Contents xv

Part IV The Thyroid Gland

Violet Fazal-Sanderson

26 Thyroid Anatomy and Physiology������������������������������������������������ 497

Chloe Broughton and Bushra Ahmad
27 Thyroid Investigations ������������������������������������������������������������������ 505
Victoria J. Stokes, Rabia Arfan, Theingi Aung,
and Violet Fazal-Sanderson
28 Hyperthyroidism in Adults������������������������������������������������������������ 519
Violet Fazal-Sanderson, Niki Karavitaki, and Radu Mihai
29 Thyroid Cancer������������������������������������������������������������������������������ 557
Ingrid Haupt-Schott, Geraldine Hamilton, and Petros Perros
30 Diagnosis and Management of Hypothyroidism in Adults�������� 581
Raluca-Alexandra Trifanescu and Catalina Poiana
31 Thyroid Eye Disease���������������������������������������������������������������������� 593
Rebecca Ford and Violet Fazal-Sanderson
32 Disorders of the Thyroid in Childhood
and Adolescence ���������������������������������������������������������������������������� 609
Suma Uday, Christine Davies, and Helena Gleeson
33 Thyroid Disease in Pre- and Post-Pregnancy������������������������������ 629
Dev A. Kevat and Lucy Mackillop

Part V The Adrenal Gland

Sofia Llahana

34 Anatomy and Physiology of the Adrenal Gland�������������������������� 645

Phillip Yeoh
35 Diagnosis and Management of Congenital Adrenal
Hyperplasia in Children and Adults�������������������������������������������� 657
Alessandro Prete, Chona Feliciano, Irene Mitchelhill,
and Wiebke Arlt
36 Adrenal Tumours: Adrenocortical Functioning Adenomas,
Pheochromocytomas, Incidentalomas, and Adrenocortical
Cancer �������������������������������������������������������������������������������������������� 679
Andrew P. Demidowich, Miriam Asia, and Jérôme Bertherat
37 Diagnosis and Management of Adrenal Insufficiency
in Children and Adults������������������������������������������������������������������ 705
Sofia Llahana, Irene Mitchelhill, Phillip Yeoh,
and Marcus Quinkler
xvi Contents

Part VI Female Endocrinology and Reproduction

Sofia Llahana and Gerard S. Conway
38 Anatomy and Physiology of the Female Reproductive System������ 739
Artemis Vogazianou
39 Assessment and Management of Women with Polycystic
Ovary Syndrome (PCOS)�������������������������������������������������������������� 753
Rhonda Garad, Soulmaz Shorakae, and Helena Teede
40 Diagnosis and Management of Turner Syndrome
in Children and Adults������������������������������������������������������������������ 771
Helen E. Turner and Irena R. Hozjan
41 Premature Ovarian Insufficiency, Menopause,
and Hormone Replacement Therapy ������������������������������������������ 803
Gerard S. Conway
42 The Endocrine System and Pregnancy���������������������������������������� 817
Margaret Eckert-Norton and Saundra Hendricks

Part VII Male Endocrinology and Reproduction

Andrew A. Dwyer and Sofia Llahana

43 Anatomy and Physiology of the

Hypothalamic-Pituitary-­Gonadal (HPG) Axis���������������������������� 839
Andrew A. Dwyer and Richard Quinton
44 Classification of Hypothalamic-­Pituitary-­Gonadal
(HPG) Axis Endocrine Disorders ������������������������������������������������ 853
Andrew A. Dwyer and Richard Quinton
45 Evaluation of Endocrine Disorders of the
Hypothalamic-Pituitary-Gonadal (HPG) Axis���������������������������� 871
Andrew A. Dwyer and Frances J. Hayes
46 Testosterone Therapy in Adult Men with
Hypogonadism�������������������������������������������������������������������������������� 885
Sofia Llahana
47 Spermatogenesis and Assisted Fertility Treatment �������������������� 903
Andrew A. Dwyer, Elizabeth Williamson, Margaret G. Au,
and Channa Jayasena
48 Diagnosis and Management of Erectile Dysfunction
in Men �������������������������������������������������������������������������������������������� 925
Fiona Holden, Clare Akers, and Sofia Llahana
49 Genetic Counselling and Psychosexual Considerations
in Male Health and Reproduction������������������������������������������������ 943
Margaret G. Au and Sue Jackson
Contents xvii

Part VIII Parathyroid, Calcium and Bone Disorders

Ann Robinson and Cecilia Follin

50 Hyperparathyroidism and Hypoparathyroidism������������������������ 957

Amy Mundy and Rachel Crowley
51 Calcium Disorders ������������������������������������������������������������������������ 975
Arthur D. Conigrave and Marsha M. van Oostwaard
52 Congenital and Acquired Bone Disorders in Children
and Adults �������������������������������������������������������������������������������������� 989
Kirtan Ganda, Klaus Sommer, and Anne L. Ersig
53 Osteoporosis������������������������������������������������������������������������������������ 1005
Sherwin Criseno
54 Vitamin D Deficiency and Treatment in Children and Adults ����� 1037
Yuk Fun Chan, Kerry-Lee Milner, Chris White,
and Pauline Musson

Part IX Obesity and Disorders of Lipid Metabolism

Cecilia Follin

55 Dietary and Behavioural Interventions in the

Management of Obesity���������������������������������������������������������������� 1065
Clare Grace and Adrian Brown
56 Assessment of the Patient with Obesity and Bariatric
Surgical Interventions�������������������������������������������������������������������� 1085
Saira Hameed and Harvinder Chahal
57 Lipid Disorders and Familial Hypercholesterolaemia���������������� 1101
Alison Pottle

Part X Late Effects of Cancer Treatment in Relation to Endocrinology

Cecilia Follin
58 Transition of Childhood Cancer Survivors��������������������������������� 1123
Tanya L. Urquhart-Kelly and Jerry K. Wales
59 Endocrinopathy After Childhood Cancer Treatment���������������� 1133
Cecilia Follin
60 Neurocognitive Dysfunction and Psychosocial Issues���������������� 1149
Katharina Roser, Gisela Michel, and Katrin Scheinemann

Part XI Endocrine Emergencies

Philip Yeoh and Anne Marland

61 Management of Hyponatraemia in Adults and Children���������� 1163

Phillip Yeoh and Anne Marland
xviii Contents

62 Prevention and Management of Adrenal Crisis in Children

and Adults �������������������������������������������������������������������������������������� 1183
Sofia Llahana, Kathrin Zopf, Irene Mitchelhill, and Ashley
Grossman
63 Thyroid Emergency: Thyroid Storm and Myxoedema Coma�������� 1207
Paul V. Carroll
64 Diagnosis and Management of Pituitary Apoplexy
in Adult Patients���������������������������������������������������������������������������� 1217
Stephanie E. Baldeweg

Part XII Neuroendocrine Tumours and Multiple Endocrine Neoplasia

Mike Tadman

65 Neuroendocrine Tumours�������������������������������������������������������������� 1229

Mike Tadman, Philippa Davies, Tara Whyand, and Lee Martin
66 Multiple Endocrine Neoplasia������������������������������������������������������ 1259
Mike Tadman and Lee Martin

Part XIII Advanced Practice Nursing in Endocrinology

Sofia Llahana

67 Conceptualization, Definition, and Competencies

of Advanced Practice Nursing with a Focus on
Endocrinology�������������������������������������������������������������������������������� 1281
Sofia Llahana, Andrew A. Dwyer, and Christine Yedinak
68 Role Development and Performance Facilitators
in Advanced Practice Nursing������������������������������������������������������ 1303
Sofia Llahana
69 Research and Evidence-Based Practice: The Nurse’s Role�������� 1321
Lesley Baillie, Debbie Carrick-Sen, Anne Marland,
and Margaret F. Keil
About the Editors

Sofia Llahana, DNSc, MSc, BSc(Hons), RN, INP

is a Senior Lecturer, Education and Research, and
Programme Director for Advanced Clinical Practice at
City, University of London. Dr Llahana was the first
consultant nurse in endocrinology in the United
Kingdom and worked at University College Hospital
in London where she continues to maintain an honor-
ary position. Her clinical and research interest is in
­pituitary and adrenal ­conditions, reproductive endocri-
nology, men’s health, self-management, adherence to
medication and behavioural medicine. Her current
research portfolio includes ongoing and new investiga-
tor-led and collaborative national and European stud-
ies in adrenal insufficiency, testosterone replacement
therapy, male reproduction, growth hormone defi-
ciency, and type 2 diabetes. Dr Llahana is the Chair of
the Nurses Committee and a member of the Executive
Committee of the European Society of Endocrinology
(ESE), a board member of the Federation of
International Nurses in Endocrinology (FINE), and the
only nurse member in the Scientific Committee for the
International Congress in Men’s Health. She also
holds affiliations with several learned societies and
patient advocacy groups in endocrinology.

Cecilia Follin graduated as a registered nurse from

the Institution of Healthcare Science at the Medical
Faculty of Lund University in Sweden. Dr Follin
has over 15 years of experience from the field of
endocrinology. She holds particular interests in late
complications after childhood cancer and pituitary
and hypothalamic disorders. Cecilia is initiator and
chair of the Nordic Network of Endocrine Nurses.
In 2010, Dr. Follin was awarded with a PhD degree
in endocrinology. The thesis was titled “Late compli-
cations of childhood acute lymphoblastic leukemia
(ALL), with special reference to hormone secretion,

xix
xx About the Editors

cardiovascular risk and bone health.” In 2010–2012,

Cecilia had a postdoc position at the Institution of
Clinical Sciences, and currently she has a position as
researcher and senior teacher at Lund University. Dr.
Follin has published numerous papers.

Christine Yedinak, DNP, FNP-BC, MN, Grad

DipEd, RN is a doctor of nursing practice and a
board-certified family nurse practitioner. She is an
assistant professor at the Northwest Pituitary Center,
Oregon Health & Sciences University, Portland,
Oregon, USA. Dr. Yedinak completed her under-
graduate training in Australia and received her post-
graduate diploma in tertiary education at the
University of Southern Queensland, Toowoomba.
She completed her postgraduate and doctoral stud-
ies at Oregon Health & Sciences University,
Portland, Oregon. Her ongoing research focus is on
quality of life and clinical outcomes for patients
with pituitary diseases. Dr. Yedinak is president of
the Endocrine Nurses Association (USA) and a
board member of the European Society of
Endocrinology Nurses’ Group. She is co-founder
and president of the Federation of International
Nurses in Endocrinology (FINE).

Ashley Grossman, BA, BSc, MD, FRCP,

FMedSci initially graduated with a BA in psy-
chology and social anthropology from the
University of London, then entered University
College Hospital Medical School in London, and
received the University Gold Medal in 1975. He
also obtained a BSc in ­ neuroscience. Professor
Grossman joined the Department of Endocrinology
at St. Bartholomew’s Hospital where he spent most
of his career, eventually as professor of neuroendo-
crinology, but then moved to become professor of
endocrinology at the University of Oxford in the
Oxford Centre for Diabetes, Endocrinology and
Metabolism. Most recently, he has moved to the
Royal Free London where he has specialized in
neuroendocrine tumors. In 1999, he was appointed
a fellow of the Academy of Medical Sciences, and
in 2011, he was made a fellow of Green Templeton
College at the University of Oxford. Professor
Grossman has published more than 900 research
About the Editors xxi

papers and reviews. He has a major interest in

tumors of the hypothalamo-pituitary axis, espe-
cially Cushing’s disease, but his clinical concern
and research have expanded increasingly to include
broad areas of endocrine oncology, most especially
neuroendocrine tumors of all types, including
pheochromocytomas, paragangliomas, adrenocor-
tical cancer, medullary thyroid cancer, and heredi-
tary endocrine tumor syndromes. He is past
president of the European Neuroendocrine
Association (ENEA), past chairman of the UKI
Neuroendocrine Tumour Society (UKINETS), and
past president of the Society of Endocrinology and
the Pituitary Society. He was previously editor of
the journal, Clinical Endocrinology; is on the edito-
rial board of the major textbook, Endocrinology, by
De Groot and Jameson; is vice chairman of the
major online textbook, Endotext.org; and serves on
the editorial boards of many journals.

About the Part Editors

Kate Davies, RN(Child) BSc(Hons) MSc

PGDip has over 25 years of experience as a chil-
dren’s nurse, with over 18 years in pediatric endocri-
nology. She has subspecialized in growth and puberty,
Cushing’s syndrome, multiple endocrine neoplasia in
children, neuroendocrine late effects of childhood
brain tumors, adrenal disorders, and disorders of sex
development. She is currently a senior lecturer in
children’s nursing and course director of the PGDip/
MSc Children’s Advanced Nurse Practitioner pro-
gram at London South Bank University, UK. She has
been chair of the Royal College of Nursing Paediatric
Endocrine Special Interest Group (2002–2008), a
member of the UK Society of Endocrinology Nurse
Committee (2012–2017), and is currently secretary
of the European Society of Paediatric Endocrine
Nurses Group. She was awarded the BSPED Ipsen
Paediatric Endocrine Nurse Award in 2014. Kate is a
fellow of the Higher Education Academy, a NMC-
registered nurse teacher, and a children’s advanced
nurse practitioner.
xxii About the Editors

Margaret F. Keil, PhD, CRNP is a board-certified

pediatric nurse practitioner with 30+ years of experi-
ence in pediatric nursing caring for children with
chronic medical conditions in a variety of clinical set-
tings. Dr. Keil received her PhD in nursing from the
Uniformed Services University of the Health
Sciences and is a graduate of the University of
Colorado and Georgetown University. Dr. Keil is a
clinical researcher at the National Institutes of Health;
her research focuses on biobehavioral outcomes of
early life adversity and quality of life and other out-
comes associated with chronic endocrine disorders in
children. Dr. Keil has authored or co-authored
numerous articles published in peer-reviewed jour-
nals on pediatric endocrine disorders, including
Cushing syndrome, quality of life outcomes, congen-
ital adrenal hyperplasia, obesity, and pituitary tumors.
She holds leadership positions in the Pediatric
Endocrinology Nurses Society and the Cushing
Support and Research Foundation and is a member of
the European Society of Endocrinology and the
Federation of International Nurses in Endocrinology.

Judith P. van Eck is one of the first advanced

practice nurses specialized in endocrinology in the
Netherlands. Her career in nursing started in 2004
when she received her bachelor degree in nursing
science. Afterward, she worked from 2004 to 2008
as a registered nurse on the clinical department of
internal medicine at the Erasmus Medical Center
in Rotterdam, the Netherlands. From 2008 to 2010,
she followed the Master in Advanced Nursing
Practice at Rotterdam University of Applied
Sciences. From 2010 until 2018, she worked as a
nurse practitioner for the Pituitary Center at the
Erasmus Medical Center in Rotterdam, the
Netherlands. She was also running a nurse-led
clinic for patients with radiation induced hypopitu-
itarism. Currently, she works as a nurse practitio-
ner at the department of Pediatric Endocrinology at
Erasmus MC- Children’s Hospital in Rotterdam,
The Netherlands. She also runs a nurse-led clinic
for patients with radiation induced hypopituita-
rism. She has been a member of the ESE nurses
working group from 2013 to 2017, and currently,
she is a member of the Dutch Endocrine Nurses
Group.
About the Editors xxiii

Violet Fazal-Sanderson’s, RGN, BSc(Hons),

MSc, IP nursing career took off in Oxford where
she worked for several years as a staff nurse in the
intensive care unit at the Oxford University
Hospitals NHS Foundation Trust. She graduated
with a BSc (hons) in critical care nursing at Oxford
Brookes University. From 2000 to 2016, she
worked in the endocrine investigations unit as an
advanced nurse practitioner at the Oxford Centre
for Diabetes, Endocrinology and Metabolism. She
developed an interest in acromegaly and thyroid
nurse-led clinics and involved herself in 40
research projects from which emerged several pub-
lished abstracts and 2 nurse awards.
In 2017, she gained an MSc in endocrinology and
now works as a senior endocrine clinical specialist
nurse at the Royal Berkshire Hospital NHS
Foundation Trust, Reading, and continues to work in
endocrinology and thyroid virtual nurse-led clinics.
Violet is a member of the British Society for
Endocrinology Nurse Committee and the UK TEDct.

Gerard S. Conway is a consultant endocrinologist

at University College London Hospitals and profes-
sor of clinical medicine in the Institute for Women’s
Heath, University College London. His clinical prac-
tice covers general endocrinology including pituitary,
adrenal, thyroid, and reproductive endocrinology.
His clinical research interests are in the field of
reproductive endocrinology particularly polycystic
ovary syndrome, ovarian and testicular function,
disorders of sexual development, and Turner syn-
drome. This research has formed the basis of over
160 academic publications.
Professor Conway qualified from the Royal
London Hospital in 1981 and trained in diabetes,
endocrinology, and general medicine in several
centers in Central London. He has been professor
of clinical medicine in the Institute for Women’s
Health UCL since 2012.
With a major interest in teaching, Professor
Conway lectures in reproductive endocrinology, for
the Society for Endocrinology, the Royal College
of Obstetricians and Gynaecologists, and interna-
tionally with the endocrine societies in the USA,
Sri Lanka, India, New Zealand, Australia, Japan,
and throughout Europe.
xxiv About the Editors

Andrew A. Dwyer, PhD, FNP-BC, FNAP is a

board-certified family nurse practitioner with 18+
years of experience in reproductive endocrinology
and translational research at the Massachusetts
General Hospital (MGH) in Boston (USA) and the
University Hospital of Lausanne (CHUV) in
Switzerland. Professor Dwyer specializes in
genetic disorders of growth/puberty and has helped
develop and test structured transitional programs
for young adults with chronic endocrine condi-
tions. He presents internationally and has authored/
co-authored more than 50 articles on these topics.
He holds leadership positions in several organiza-
tions including the European Society of
Endocrinology, Pediatric Endocrine Nursing
Society, European Society of Paediatric Endocrine
Nursing, International Society of Nurses in
Genetics, and Global Genomic Nursing Alliance.
In 2018, Professor Dwyer was inducted into the
National Academies of Practice (nursing) as a dis-
tinguished fellow.

Ann Robinson is an endorsed nurse practitioner

(NP) with experience in both public and private
sectors. With a background in diabetes and endo-
crine nursing, her main area of clinical work is
now bone health and fracture prevention in high-
risk populations. In addition, Ann sits on the gov-
erning board of the SOS Fracture Alliance and is
past president of the Endocrine Nurses Society of
Australasia. Ann works at Gold Coast Health as a
nurse practitioner collaborating between hospital
and community services to improve osteoporosis
awareness and reduce the burden of osteoporotic
fractures. She collaborates with the orthopedic
teams and has an interest in when to commence
treatment, for how long, and when, if ever to stop
treatment.
About the Editors xxv

Phillip Yeoh, RN, BSc, MSc, PhD(c) completed

registered nurse training in London, BSc from the
University of Manchester, and MSc from Brunel
University. Philip is currently doing a PhD in
Nursing at King’s College in London. He is consul-
tant nurse in endocrinology and manager for
Endocrine and Diabetes Department within the
London Clinic, providing inpatient and outpatient
care. His interests in endocrinology focus on adre-
nal diseases, pituitary conditions, Cushing’s dis-
ease, acromegaly, neuroendocrine conditions,
parathyroid diseases, thyroid cancers, Conn’s syn-
drome, endocrine malignancy such as adrenocorti-
cal carcinoma, endocrine testing, endocrine nurse
clinical roles, and endocrine nurse educations. He
is co-author of Competency Framework for Adult
Endocrine Nursing (Society for Endocrinology)
editions I and II. Currently, he is involved in vari-
ous research projects looking at dynamic function
tests and endocrine nurse role in continuous subcu-
taneous hydrocortisone infusion pump for patients
with adrenal insufficiency. He is coordinator for
Federation of International Nurses in Endocrinology.
He was a nurse committee member for European
Society of Endocrinology and Society for
Endocrinology. He is also a trustee for Addison’s
Disease Self-Help Group UK.

Anne Marland, RGN, INP, BSc, MSc, PhD(c) is

advanced nurse practitioner in adult endocrinology
and independent nurse prescriber (INP) at the
Oxford Centre for Diabetes, Endocrinology and
Metabolism (OCDEM) in the UK. Anne worked in
the Neuroscience Department in Oxford, and in
1998, she took on a senior research nurse role in
OCDEM and, following this, advanced nurse prac-
titioner. Anne has a keen interest in the clinical area
of “late effects in endocrinology” and is currently
studying for a PhD in this area. She is the patient
and public involvement representative for the NIHR
xxvi About the Editors

for endocrinology and rare disease in the UK. Anne

has a keen interest in education and regularly lec-
tures worldwide. She chairs the working party
which developed the Society for Endocrinology
MSc in Adult Endocrine Nursing in collaboration
with Oxford Brookes University in the UK. Anne is
the current chair for the British Society for
Endocrinology Nurse Committee and member of
the Public Engagement Committee.

Mike Tadman is a cancer nurse specialist with

over 20 years of experience both in practice and
education, mainly within Oxford, but has also prac-
ticed in Edinburgh and briefly in Melbourne. He
set up the Neuroendocrine Tumours Specialist
Nursing Service at the Oxford University Hospitals
NHS Foundation Trust in 2013. He is an active
member of UKINETs and ENETs and has pre-
sented regularly at national and international con-
ferences on NETs. He has completed a survey of
how centers commence and he has recently pub-
lished research into the use of somatostatin ana-
logue test dosing and urine 5HIAA testing. He is
author of the OUP Cancer Nursing Handbook, hav-
ing just completed editing its 2nd edition.
Contributors

Daphne T. Adelman Division of Endocrinology, Metabolism and Molecular

Medicine, Northwestern University, Feinberg School of Medicine, Chicago,
IL, USA
Bushra Ahmad Bristol Royal Infirmary, University of Bristol, Bristol, UK
Clare Akers Urology Department, Westmorland Street Hospital, University
College London Hospitals NHS Foundation Trust, London, UK
Ahmed Al Sajwani Department of Endocrinology, Tallaght Hospital,
Dublin and Trinity College, Dublin, Ireland
Susie Aldiss Faculty of Health and Medical Sciences, University of Surrey,
Surrey, UK
Wiebke Arlt Queen Elizabeth Hospital Birmingham, University Hospitals
Birmingham NHS Foundation Trust, Birmingham, UK
Miriam Asia Department of Endocrinology, Birmingham University
Hospital, Birmingham, UK
Margaret G. Au Department of Pediatrics, Cedars-Sinai Medical Center,
Los Angeles, CA, USA
Theingi Aung Centre for Diabetes and Endocrinology, Royal Berkshire
Hospital NHS Foundation Trust, Reading, UK
Lesley Baillie School of Health, Wellbeing and Social Care Nursing, The
Open University, Milton Keynes, UK
Stephanie E. Baldeweg Department of Diabetes and Endocrinology,
University College London Hospitals, London, UK
Kelly Mullholand Behm Orlando, FL, USA
Sarah Benzo Surgical Neurology Branch, National Institute of Neurologic
Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
Jérôme Bertherat Service d’Endocrinologie, Hôpital Cochin, Paris, France
Beth Brillante National Institutes of Health, National Institute of Dental and
Craniofacial Research, Craniofacial and Skeletal Diseases Branch, SCSU,
Bethesda, MD, USA

xxvii
xxviii Contributors

Chloe Broughton North Bristol NHS Trust, Bristol, UK

Adrian Brown Imperial College London, London, UK
Debbie Carrick-Sen School of Nursing, Institute of Clinical Sciences,
College of Medical and Dental Sciences, University of Birmingham,
Birmingham, UK
Paul V. Carroll Department of Endocrinology, Guy’s & St. Thomas’ NHS
Foundation Trust, DEDC 3rd Floor Lambeth Wing, St. Thomas’ Hospital,
London, UK
Harvinder Chahal Imperial Weight Centre, St. Mary’s Hospital, Imperial
College Healthcare NHS Trust, London, UK
Yuk Fun Chan Department of Endocrinology and Metabolism, Prince of
Wales Hospital, Randwick, NSW, Australia
Kathryn Clark University of Michigan Hospital, Ann Arbor, MI, USA
Sharron Close Emory School of Medicine, Emory University School of
Nursing, The eXtraordinarY Clinic at Emory, Atlanta, GA, USA
Arthur D. Conigrave Faculty of Medicine and Health, University of
Sydney, Sydney, NSW, Australia
Gerard S. Conway Institute for Women’s Health, University College
London, London, UK
Sherwin Criseno University Hospitals Birmingham NHS Foundation Trust,
Birmingham, UK
Rachel Crowley St. Vincent’s University Hospital and University, College
Dublin, Dublin, Ireland
Marina Cunha-Silva Disciplina de Endocrinologia e Metabologia do
Hospital das Clínicas da Faculdade de Medicina da Universidade de São
Paulo, Brazil, São Paulo, Brazil
Christine Davies Children’s Hospital for Wales, Cardiff and Vale UHB
University Hospital of Wales (UHW), Cardiff, UK
Kate Davies Department of Advanced and Integrated Practice, London
South Bank University, London, UK
Philippa Davies NET Unit, Royal Free London NHS Foundation Trust,
London, UK
Andrew P. Demidowich National Institutes of Health, Bethesda, MDUSA
Louise Doodson Great Ormond Street Hospital for Children NHS Trust,
London, UK
Andrew A. Dwyer William F. Connell School of Nursing, Boston College,
Chesnut Hill, MA, USA
Margaret Eckert-Norton SUNY Downstate, Brooklyn, NY, USA
Contributors xxix

Anne L. Ersig UW-Madison School of Nursing, UW Health American

Family Children’s Hospital, Madison, WI, USA
Violet Fazal-Sanderson Centre for Diabetes and Endocrinology, Royal
Berkshire Hospital NHS Foundation Trust, Reading, UK
Chona Feliciano Queen Elizabeth Hospital Birmingham, University
Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Cecilia Follin Department of Endocrinology, Skane University Hospital,
Lund, Sweden
Rebecca Ford Bristol Eye Hospital, University Hospitals Bristol NHS Trust,
Bristol, UK
Kirtan Ganda Concord Hospital, Sydney, NSW, Australia
Rhonda Garad Monash Centre for Health Research and Implementation
(MCHRI), Monash University, Clayton, VIC, Australia
Claire Gilbert Great Ormond Street Hospital for Children NHS Trust,
London, UK
Helena Gleeson Department of Endocrinology, University Hospitals
Birmingham NHS Foundation Trust, Birmingham, UK
Clare Grace Relish Nutrition Consultancy, North Yorkshire, UK
Ashley Grossmann Royal Free Hospital, London, UK
Green Templeton College, University of Oxford, Oxford, UK
Barts and the London School of Medicine, London, UK
Lori Guthrie National Institutes of Health, National Institute of Dental and
Craniofacial Research, Craniofacial and Skeletal Diseases Branch, SCSU,
Bethesda, MD, USA
Saira Hameed Imperial Weight Centre, St. Mary’s Hospital, Imperial
College Healthcare NHS Trust, London, UK
Geraldine Hamilton Macmillan Support Line, Macmillan Cancer Support,
Glasgow, UK
Ingrid Haupt-Schott Velindre NHS Trust, Velindre Cancer Centre, Cardiff,
UK
Christina Hayes Surgical Neurology Branch, National Institute of
Neurologic Disorders and Stroke, National Institutes of Health, Bethesda,
MD, USA
Frances J. Hayes Endocrine Division, Harvard Medical School,
Massachusetts General Hospital, Boston, MA, USA
Saundra Hendricks Department of Medicine, Center of Bioenergetics,
Houston Methodist Hospital, Houston, TX, USA
Fiona Holden Urology Department, Westmorland Street Hospital,
University College London Hospitals NHS Foundation Trust, London, UK
xxx Contributors

Jürgen Honegger Department of Neurosurgery, University of Tuebingen,

Tuebingen, Germany
Irena R. Hozjan Endocrine Program, Department of Pediatrics, The
Hospital for Sick Children, Toronto, ON, Canada
Khalid Hussain Great Ormond Street Hospital for Children NHS Trust,
London, UK
Sue Jackson Psychology Department, University of the West of England,
Bristol, UK
Channa Jayasena Reproductive Endocrinology and Andrology, Imperial
College and Hammersmith Hospital, London, UK
Peggy Kalancha Clinical Resource, Pediatric Endocrine and Gynecology
Clinics, Alberta Children’s Hospital, Calgary, AB, Canada
Niki Karavitaki Institute of Metabolism and Systems Research, University
of Birmingham and Queen Elizabeth Hospital, Birmingham, UK
Margaret F. Keil Eunice Kennedy Shriver National Institute of Child Health
and Human Development, National Institutes of Health, Bethesda, MD, USA
Dev A. Kevat Monash Health and Western Health, Melbourne, VIC,
Australia
Nicole Kirouac St. Amant Inc., Winnipeg, MB, Canada
Kathryn Evans Kreider Duke University School of Nursing and Duke
University Medical Center, Durham, NC, USA
Ana Claudia Latronico Disciplina de Endocrinologia e Metabologia do
Hospital das Clínicas da Faculdade de Medicina da Universidade de São
Paulo, Brazil, São Paulo, Brazil
Megan K. Lessig Division of Endocrinology and Diabetes, Children’s
Hospital of Philadelphia, Philadelphia, PA, USA
Karen J. P. Liebert Neuroendocrine Unit, Massachusetts General Hospital,
Boston, MA, USA
Terri H. Lipman Division of Endocrinology and Diabetes, Children’s
Hospital of Philadelphia, Philadelphia, PA, USA
Sofia Llahana School of Health Sciences, City, University of London,
London, UK
Lucy Mackillop Nuffield Department of Women’s and Reproductive Health,
University of Oxford, Level 6, Women’s Centre, John Radcliffe Hospital,
Oxford, UK
Anne Marland Oxford Centre for Diabetes, Endocrinology and Metabolism,
Radcliffe Department of Medicine, University of Oxford, Oxford, UK
Contributors xxxi

Lee Martin Barts Health NHS Trust, The Royal London Hospital, London,
UK
Raven McGlotten National Institutes of Health, Bethesda, MD, USA
Gisela Michel Department of Health Sciences and Health Policy, University
of Lucerne, Luzern, Switzerland
Radu Mihai Department of Endocrine Surgery, Churchill Cancer Centre,
Oxford University Hospitals Foundation Trust, Oxford, UK
Kerry-Lee Milner Department of Endocrinology and Metabolism, Prince
of Wales Hospital, Randwick, NSW, Australia
Irene Mitchelhil Department of Endocrinology, Sydney Children’s Hospital
(SCHN), Randwick, NSW, Australia
Bin Moore The Children’s Hospital, Westmead, NSW, Australia
Kate Morgan Great Ormond Street Hospital for Children NHS Trust,
London, UK
Amy Mundy McGuire Veterans Medical Center, Richmond, VA, USA
Pauline Musson Southampton Children’s Hospital, Southampton, UK
Sebastian J.C.M.M. Neggers Department of Medicine, Section
Endocrinology, Erasmus Medical Centre, Rotterdam, The Netherlands
Milla Pantovic Department of Neuroendocrinology, Clinic for
Endocrinology, Clinical Center Serbia, Belgrade, Serbia
Petro Perros Newcastle upon Tyne Hospitals NHS Foundation Trust and
Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne,
UK
Catalina Poiana Department of Endocrinology, “Carol Davila” University
of Medicine and Pharmacy, Bucharest, Romania
Vera Popovic Department of Neuroendocrinology, Clinic for Endocrinology,
Clinical Center Serbia, Belgrade, Serbia
Alison Pottle Royal Brompton and Harefield NHS Foundation Trust,
London, UK
Alessandro Prete Queen Elizabeth Hospital Birmingham, University
Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Eileen Pyra Alberta Children’s Hospital, Endocrine Clinic, Calgary, AB,
Canada
Marcus Quinkler Department of Medicine for Endocrinology, Diabetes
and Nutrition Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany
Richard Quinton Newcastle-upon-Tyne Hospitals Foundation NHS Trust
(Royal Victoria Infirmary), Newcastle-upon-Tyne, UK
Another random document with
no related content on Scribd:
 1020 Metropolitan Life Building
Minneapolis, Minn.

ADVERTISING RATES

One page, each insertion $15.00

Half page, each insertion 8.00
Quarter page, each insertion 4.00
One inch, one column, each insertion 1.00
Half inch, one column, each insertion .50

Discounts for insertions of one advertisement for three months or

more.

The Curse of Race Prejudice

James F. Morton, Jr., A.M., Author and Publisher
Forceful, rational, comprehensive. An arsenal of facts and
unanswerable arguments. Invaluable for propaganda. Read the
chapter on “The Bugbear of Social Equality,” which is a veritable eye-
opener. Thousands already sold. Agents wanted everywhere.
PRICE 25 CENTS
Address the Author at 244 West 143d Street,
New York, N. Y.

Mme. BECK’S School of Dressmaking

Designing, Cutting, Fitting, Embroidering and Ladies’ Tailoring
Taught by the Improved French System

Separate Courses in Any of the Branches, and Diplomas Awarded

the Successful Graduates

Day and Evening Classes

 238 WEST 53d STREET NEW YORK CITY

The Firm for the Negro Farmers and Shippers to Deal

With
Try Us Before Shipping Elsewhere.

Fruits and Vegetables Oysters and Game Poultry and Eggs

COTTMAN & COTTMAN

WHOLESALE COMMISSION MERCHANTS. 107 Pine Street,
Philadelphia, Pa.
Reference: The People’s Savings Bank Bell ’Phone Connection:
Lombard 4035

NYANZA DRUG CO.

(Incorporated.)

35 W. 135th ST., NEW YORK CITY

CAPITAL STOCK, $15,000
Shares $5.00
Write for information. The best paying investment ever offered our
people.

NYANZA PHARMACY
is the only colored Drug Store in New York City, and the purpose of
the Corporation is to establish chains of stores, carrying Drugs and
everything incidental to the Drug business. It is really the
indisputable duty of every self-respecting member of the race to give
it his support.
AGENTS WANTED EVERYWHERE
 $100,000 STOCK ISSUE
TO BUILD AN
Auditorium in Greater New York
CONTAINING
Reception, Concert and Banquet Halls, Modern Offices and Lodge
Rooms

This proposition is bound to succeed, because it is giving the people

what they want.
We are offering

10,000 Shares at $10 Each, Par Value

Stock sold in blocks to suit the investor on easy terms.

The capital already in hand and the rapid increase of business
means the realisation of the Auditorium. This enterprise assures
each investor Safety of Capital and Growth of Income. Call or write
for further particulars.
I. L. MOORMAN, Mgr., 83 W. 134th St.

SOLOMON GARRETT
Tonsorial Artist
782 Fulton Street, near Adelphi Street

BROOKLYN, N. Y.

All Kinds of Workmanship

Cigars and Tobacco for Sale
Daily and Weekly Papers and Magazines

Brooklyn Agents for THE CRISIS

 How to Elevate the Moral and Civic Tone of the
Negro Community

Negroes—good, bad and indifferent—as long as they have

lived in tenements, have had to live shamefully intermingled.
Formerly they were forced to live in ramshackle tenements that
had been abandoned by the whites, at exorbitant rents for
wretched accommodations. But now, thanks to the thrift and
enterprise of certain progressive Negro real estate agents, they
may live in houses having the same conveniences and
accommodations as the whites. While, happily, the physical
surroundings of the Negro tenant have been radically altered,
unhappily his moral surroundings remain unchanged. How,
then, can we improve his moral surroundings? Co-operation is
a sine qua non in the solution of this problem. Tenants MUST
co-operate with their agents and agents MUST co-operate with
one another in ameliorating the moral and civic condition of
Negro communities. We can’t lean on the landlord. He is an
indifferent third party. He cares not, so to speak, whether his
house is tenanted with respectable or disrespectable tenants, so
long as it is full and he gets his rents. If he’s at all concerned
about the disrespectable or respectable tenants in his house, it’s
only to the extent that he’s afraid the former may be the cause
of some or all of the latter moving, thus leaving him with some
vacancies.
The present moral conditions of Negro tenantry are indeed
bad. The individual efforts of certain Negro agents toward
bettering the conditions have been praiseworthy, to say the
least, but as far as making any progress toward the desired goal
is concerned, such efforts must needs be and practically have
been of little or no avail. What is the desirable goal is too
obvious to command explanation. But how to reach that goal is
the matter under consideration. In the first place, we repeat
that the united efforts of tenants and agents are the
desideratum.
Let the agent compel a prospective tenant to furnish
references satisfying fair and reasonable requirements as
imposed by, agreed upon and accepted in toto by all agents. The
respectable tenant will be glad to do it. Any tenant not
furnishing such references should be “jim-crowed,” as it were,
from decent neighborhoods.
This matter of bettering the moral and civic condition of
Negro communities is a case of a wheel within a wheel. As has
been emphasized before, the agent can do absolutely nothing
without co-operation. Ministers wielding great influence over
large congregations can lend a powerfully helping hand, if they
will. We must all pull together. We cannot work resultfully in
factions. It is unquestionably within our power to do it, if all
others do their respective parts and the colored real estate
agent does his.
Desirable Apartments for Desirable Tenants Also Homes
for Sale on Easy Terms

Philip A. Payton, Jr., Company

New York’s Pioneer Negro Real Estate Agents
BROKERS====APPRAISERS

TELEPHONES
917–918 HARLEM 67 West 134th St., New York City

Do You Want a
Position?

Best Places
 Best Families

The New York and New Jersey Industrial Exchange, through

its Employment Agency Department, furnishes more Colored
Help to the leading families in the city and in the suburban
towns than any other medium in New York.
It is located in the acknowledged best section of the city,
being in the Henry Phipps’ Model Tenements for Colored
Families. No other Exchange is so well patronized by the
foremost families, many of whom have never employed Colored
Help before.
Our demand for competent Southern Help exceeds the
supply many times over. Call and register. No charge. Bring
your references. We can place you in a good position. If
inconvenient to pay our required office fee, you are at liberty to
take advantage of our Credit System. This new feature has
proven extremely beneficial to many worthy persons seeking
employment.
N. Y. & N. J. Industrial Exchange
237–239 West 63d Street
Telephones 5016–4546 Columbus

Cosmopolitan Automobile School

The aim of the School will
be to give its students a
sufficient knowledge of the
theory and practice of
Automobile and
Automobiling to enable them
to meet the emergencies that
constantly arise to make
those who complete the
course competent to run
machines, take them apart
and assemble them properly,
and to make such repairs as may be necessary and possible on
the road.
TUITION—Six weeks’ course, including Shop and Road
Work, $25: installments if you wish, payable $5 on enrollment
and $20 by the completion of the fourth week.
SHOP WORK—Consists of naming all the parts of the
automobile, taking the engine and the rest of the automobile
apart and putting them together again properly, and making
such repairs as may be necessary and possible.
ROAD WORK—When the shop work is complete the student
takes up the operating and handling of cars on the road until he
is competent.
If there is any special information which you desire
respecting the course or opportunities in the automobile
business we shall be glad to bear from you.
COSMOPOLITAN AUTO CO. of New York
Telephone 803 Columbus School: Hotel Maceo, 213 West 53d
St. LEE A. POLLARD, Mgr.
 TRANSCRIBER’S NOTES
1. Silently corrected obvious typographical errors and
variations in spelling.
2. Retained archaic, non-standard, and uncertain spellings
as printed.
3. Re-indexed footnotes using numbers.
4. A reprint edition provided by Arno Press, A Publishing
and Library Service of the New York Times, New York,
1969.
*** END OF THE PROJECT GUTENBERG EBOOK THE CRISIS ***

Updated editions will replace the previous one—the old editions

will be renamed.

Creating the works from print editions not protected by U.S.

copyright law means that no one owns a United States copyright
in these works, so the Foundation (and you!) can copy and
distribute it in the United States without permission and without
paying copyright royalties. Special rules, set forth in the General
Terms of Use part of this license, apply to copying and
distributing Project Gutenberg™ electronic works to protect the
PROJECT GUTENBERG™ concept and trademark. Project
Gutenberg is a registered trademark, and may not be used if
you charge for an eBook, except by following the terms of the
trademark license, including paying royalties for use of the
Project Gutenberg trademark. If you do not charge anything for
copies of this eBook, complying with the trademark license is
very easy. You may use this eBook for nearly any purpose such
as creation of derivative works, reports, performances and
research. Project Gutenberg eBooks may be modified and
printed and given away—you may do practically ANYTHING in
the United States with eBooks not protected by U.S. copyright
law. Redistribution is subject to the trademark license, especially
commercial redistribution.

START: FULL LICENSE

THE FULL PROJECT GUTENBERG LICENSE
 PLEASE READ THIS BEFORE YOU DISTRIBUTE OR USE THIS WORK

To protect the Project Gutenberg™ mission of promoting the

free distribution of electronic works, by using or distributing this
work (or any other work associated in any way with the phrase
“Project Gutenberg”), you agree to comply with all the terms of
the Full Project Gutenberg™ License available with this file or
online at www.gutenberg.org/license.

Section 1. General Terms of Use and

Redistributing Project Gutenberg™
electronic works
1.A. By reading or using any part of this Project Gutenberg™
electronic work, you indicate that you have read, understand,
agree to and accept all the terms of this license and intellectual
property (trademark/copyright) agreement. If you do not agree to
abide by all the terms of this agreement, you must cease using
and return or destroy all copies of Project Gutenberg™
electronic works in your possession. If you paid a fee for
obtaining a copy of or access to a Project Gutenberg™
electronic work and you do not agree to be bound by the terms
of this agreement, you may obtain a refund from the person or
entity to whom you paid the fee as set forth in paragraph 1.E.8.

1.B. “Project Gutenberg” is a registered trademark. It may only

be used on or associated in any way with an electronic work by
people who agree to be bound by the terms of this agreement.
There are a few things that you can do with most Project
Gutenberg™ electronic works even without complying with the
full terms of this agreement. See paragraph 1.C below. There
are a lot of things you can do with Project Gutenberg™
electronic works if you follow the terms of this agreement and
help preserve free future access to Project Gutenberg™
electronic works. See paragraph 1.E below.
1.C. The Project Gutenberg Literary Archive Foundation (“the
Foundation” or PGLAF), owns a compilation copyright in the
collection of Project Gutenberg™ electronic works. Nearly all the
individual works in the collection are in the public domain in the
United States. If an individual work is unprotected by copyright
law in the United States and you are located in the United
States, we do not claim a right to prevent you from copying,
distributing, performing, displaying or creating derivative works
based on the work as long as all references to Project
Gutenberg are removed. Of course, we hope that you will
support the Project Gutenberg™ mission of promoting free
access to electronic works by freely sharing Project
Gutenberg™ works in compliance with the terms of this
agreement for keeping the Project Gutenberg™ name
associated with the work. You can easily comply with the terms
of this agreement by keeping this work in the same format with
its attached full Project Gutenberg™ License when you share it
without charge with others.

1.D. The copyright laws of the place where you are located also
govern what you can do with this work. Copyright laws in most
countries are in a constant state of change. If you are outside
the United States, check the laws of your country in addition to
the terms of this agreement before downloading, copying,
displaying, performing, distributing or creating derivative works
based on this work or any other Project Gutenberg™ work. The
Foundation makes no representations concerning the copyright
status of any work in any country other than the United States.

1.E. Unless you have removed all references to Project

Gutenberg:

1.E.1. The following sentence, with active links to, or other

immediate access to, the full Project Gutenberg™ License must
appear prominently whenever any copy of a Project
Gutenberg™ work (any work on which the phrase “Project
Gutenberg” appears, or with which the phrase “Project
Gutenberg” is associated) is accessed, displayed, performed,
viewed, copied or distributed:

This eBook is for the use of anyone anywhere in the United

States and most other parts of the world at no cost and with
almost no restrictions whatsoever. You may copy it, give it
away or re-use it under the terms of the Project Gutenberg
License included with this eBook or online at
www.gutenberg.org. If you are not located in the United
States, you will have to check the laws of the country where
you are located before using this eBook.

1.E.2. If an individual Project Gutenberg™ electronic work is

derived from texts not protected by U.S. copyright law (does not
contain a notice indicating that it is posted with permission of the
copyright holder), the work can be copied and distributed to
anyone in the United States without paying any fees or charges.
If you are redistributing or providing access to a work with the
phrase “Project Gutenberg” associated with or appearing on the
work, you must comply either with the requirements of
paragraphs 1.E.1 through 1.E.7 or obtain permission for the use
of the work and the Project Gutenberg™ trademark as set forth
in paragraphs 1.E.8 or 1.E.9.

1.E.3. If an individual Project Gutenberg™ electronic work is

posted with the permission of the copyright holder, your use and
distribution must comply with both paragraphs 1.E.1 through
1.E.7 and any additional terms imposed by the copyright holder.
Additional terms will be linked to the Project Gutenberg™
License for all works posted with the permission of the copyright
holder found at the beginning of this work.

1.E.4. Do not unlink or detach or remove the full Project

Gutenberg™ License terms from this work, or any files
containing a part of this work or any other work associated with
Project Gutenberg™.
 1.E.5. Do not copy, display, perform, distribute or redistribute
this electronic work, or any part of this electronic work, without
prominently displaying the sentence set forth in paragraph 1.E.1
with active links or immediate access to the full terms of the
Project Gutenberg™ License.

1.E.6. You may convert to and distribute this work in any binary,
compressed, marked up, nonproprietary or proprietary form,
including any word processing or hypertext form. However, if
you provide access to or distribute copies of a Project
Gutenberg™ work in a format other than “Plain Vanilla ASCII” or
other format used in the official version posted on the official
Project Gutenberg™ website (www.gutenberg.org), you must, at
no additional cost, fee or expense to the user, provide a copy, a
means of exporting a copy, or a means of obtaining a copy upon
request, of the work in its original “Plain Vanilla ASCII” or other
form. Any alternate format must include the full Project
Gutenberg™ License as specified in paragraph 1.E.1.

1.E.7. Do not charge a fee for access to, viewing, displaying,

performing, copying or distributing any Project Gutenberg™
works unless you comply with paragraph 1.E.8 or 1.E.9.

1.E.8. You may charge a reasonable fee for copies of or

providing access to or distributing Project Gutenberg™
electronic works provided that:

• You pay a royalty fee of 20% of the gross profits you derive from
the use of Project Gutenberg™ works calculated using the
method you already use to calculate your applicable taxes. The
fee is owed to the owner of the Project Gutenberg™ trademark,
but he has agreed to donate royalties under this paragraph to
the Project Gutenberg Literary Archive Foundation. Royalty
payments must be paid within 60 days following each date on
which you prepare (or are legally required to prepare) your
periodic tax returns. Royalty payments should be clearly marked
as such and sent to the Project Gutenberg Literary Archive
Foundation at the address specified in Section 4, “Information
 about donations to the Project Gutenberg Literary Archive
Foundation.”

• You provide a full refund of any money paid by a user who

notifies you in writing (or by e-mail) within 30 days of receipt that
s/he does not agree to the terms of the full Project Gutenberg™
License. You must require such a user to return or destroy all
copies of the works possessed in a physical medium and
discontinue all use of and all access to other copies of Project
Gutenberg™ works.

• You provide, in accordance with paragraph 1.F.3, a full refund of

any money paid for a work or a replacement copy, if a defect in
the electronic work is discovered and reported to you within 90
days of receipt of the work.

• You comply with all other terms of this agreement for free
distribution of Project Gutenberg™ works.

1.E.9. If you wish to charge a fee or distribute a Project

Gutenberg™ electronic work or group of works on different
terms than are set forth in this agreement, you must obtain
permission in writing from the Project Gutenberg Literary
Archive Foundation, the manager of the Project Gutenberg™
trademark. Contact the Foundation as set forth in Section 3
below.

1.F.

1.F.1. Project Gutenberg volunteers and employees expend

considerable effort to identify, do copyright research on,
transcribe and proofread works not protected by U.S. copyright
law in creating the Project Gutenberg™ collection. Despite
these efforts, Project Gutenberg™ electronic works, and the
medium on which they may be stored, may contain “Defects,”
such as, but not limited to, incomplete, inaccurate or corrupt
data, transcription errors, a copyright or other intellectual
property infringement, a defective or damaged disk or other
medium, a computer virus, or computer codes that damage or
cannot be read by your equipment.

1.F.2. LIMITED WARRANTY, DISCLAIMER OF DAMAGES -

Except for the “Right of Replacement or Refund” described in
paragraph 1.F.3, the Project Gutenberg Literary Archive
Foundation, the owner of the Project Gutenberg™ trademark,
and any other party distributing a Project Gutenberg™ electronic
work under this agreement, disclaim all liability to you for
damages, costs and expenses, including legal fees. YOU
AGREE THAT YOU HAVE NO REMEDIES FOR NEGLIGENCE,
STRICT LIABILITY, BREACH OF WARRANTY OR BREACH
OF CONTRACT EXCEPT THOSE PROVIDED IN PARAGRAPH
1.F.3. YOU AGREE THAT THE FOUNDATION, THE
TRADEMARK OWNER, AND ANY DISTRIBUTOR UNDER
THIS AGREEMENT WILL NOT BE LIABLE TO YOU FOR
ACTUAL, DIRECT, INDIRECT, CONSEQUENTIAL, PUNITIVE
OR INCIDENTAL DAMAGES EVEN IF YOU GIVE NOTICE OF
THE POSSIBILITY OF SUCH DAMAGE.

1.F.3. LIMITED RIGHT OF REPLACEMENT OR REFUND - If

you discover a defect in this electronic work within 90 days of
receiving it, you can receive a refund of the money (if any) you
paid for it by sending a written explanation to the person you
received the work from. If you received the work on a physical
medium, you must return the medium with your written
explanation. The person or entity that provided you with the
defective work may elect to provide a replacement copy in lieu
of a refund. If you received the work electronically, the person or
entity providing it to you may choose to give you a second
opportunity to receive the work electronically in lieu of a refund.
If the second copy is also defective, you may demand a refund
in writing without further opportunities to fix the problem.

1.F.4. Except for the limited right of replacement or refund set

forth in paragraph 1.F.3, this work is provided to you ‘AS-IS’,
WITH NO OTHER WARRANTIES OF ANY KIND, EXPRESS
OR IMPLIED, INCLUDING BUT NOT LIMITED TO
WARRANTIES OF MERCHANTABILITY OR FITNESS FOR
ANY PURPOSE.

1.F.5. Some states do not allow disclaimers of certain implied

warranties or the exclusion or limitation of certain types of
damages. If any disclaimer or limitation set forth in this
agreement violates the law of the state applicable to this
agreement, the agreement shall be interpreted to make the
maximum disclaimer or limitation permitted by the applicable
state law. The invalidity or unenforceability of any provision of
this agreement shall not void the remaining provisions.

1.F.6. INDEMNITY - You agree to indemnify and hold the

Foundation, the trademark owner, any agent or employee of the
Foundation, anyone providing copies of Project Gutenberg™
electronic works in accordance with this agreement, and any
volunteers associated with the production, promotion and
distribution of Project Gutenberg™ electronic works, harmless
from all liability, costs and expenses, including legal fees, that
arise directly or indirectly from any of the following which you do
or cause to occur: (a) distribution of this or any Project
Gutenberg™ work, (b) alteration, modification, or additions or
deletions to any Project Gutenberg™ work, and (c) any Defect
you cause.

Section 2. Information about the Mission of

Project Gutenberg™
Project Gutenberg™ is synonymous with the free distribution of
electronic works in formats readable by the widest variety of
computers including obsolete, old, middle-aged and new
computers. It exists because of the efforts of hundreds of
volunteers and donations from people in all walks of life.

Volunteers and financial support to provide volunteers with the

assistance they need are critical to reaching Project
Gutenberg™’s goals and ensuring that the Project Gutenberg™
collection will remain freely available for generations to come. In
2001, the Project Gutenberg Literary Archive Foundation was
created to provide a secure and permanent future for Project
Gutenberg™ and future generations. To learn more about the
Project Gutenberg Literary Archive Foundation and how your
efforts and donations can help, see Sections 3 and 4 and the
Foundation information page at www.gutenberg.org.

Section 3. Information about the Project

Gutenberg Literary Archive Foundation
The Project Gutenberg Literary Archive Foundation is a non-
profit 501(c)(3) educational corporation organized under the
laws of the state of Mississippi and granted tax exempt status by
the Internal Revenue Service. The Foundation’s EIN or federal
tax identification number is 64-6221541. Contributions to the
Project Gutenberg Literary Archive Foundation are tax
deductible to the full extent permitted by U.S. federal laws and
your state’s laws.

The Foundation’s business office is located at 809 North 1500

West, Salt Lake City, UT 84116, (801) 596-1887. Email contact
links and up to date contact information can be found at the
Foundation’s website and official page at
www.gutenberg.org/contact

Section 4. Information about Donations to

the Project Gutenberg Literary Archive
Foundation
Project Gutenberg™ depends upon and cannot survive without
widespread public support and donations to carry out its mission
of increasing the number of public domain and licensed works
that can be freely distributed in machine-readable form
accessible by the widest array of equipment including outdated
equipment. Many small donations ($1 to $5,000) are particularly
important to maintaining tax exempt status with the IRS.

The Foundation is committed to complying with the laws

regulating charities and charitable donations in all 50 states of
the United States. Compliance requirements are not uniform
and it takes a considerable effort, much paperwork and many
fees to meet and keep up with these requirements. We do not
solicit donations in locations where we have not received written
confirmation of compliance. To SEND DONATIONS or
determine the status of compliance for any particular state visit
www.gutenberg.org/donate.

While we cannot and do not solicit contributions from states

where we have not met the solicitation requirements, we know
of no prohibition against accepting unsolicited donations from
donors in such states who approach us with offers to donate.

International donations are gratefully accepted, but we cannot

make any statements concerning tax treatment of donations
received from outside the United States. U.S. laws alone swamp
our small staff.

Please check the Project Gutenberg web pages for current

donation methods and addresses. Donations are accepted in a
number of other ways including checks, online payments and
credit card donations. To donate, please visit:
www.gutenberg.org/donate.

Section 5. General Information About Project

Gutenberg™ electronic works
Professor Michael S. Hart was the originator of the Project
Gutenberg™ concept of a library of electronic works that could
be freely shared with anyone. For forty years, he produced and