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R A D C L I F F E P R I M A RY C A R E
Clinical
Effectiveness
and Clinical
Governance
Made Easy
Fourth edition
Fourth Edition
Ruth Chambers
Elizabeth Boath
RADCLIFFE PUBLISHING
Oxford . New York
CRC Press
Taylor & Francis Group
6000 Broken Sound Parkway NW, Suite 300
Boca Raton, FL 33487-2742
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lishers. The information or guidance contained in this book is intended for use by medical, scientific or health-care professionals
and is provided strictly as a supplement to the medical or other professional’s own judgement, their knowledge of the patient’s
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Acknowledgements vi
Introduction 1
Overall aim of the programme 1
Objectives of this book 1
Self-assessment of where you are now with clinical
effectiveness and clinical governance 2
What are clinical effectiveness and evidence-based
healthcare? 5
What is the evidence for evidence-based healthcare? 6
Why health professionals need information 7
Are clinicians ready for evidence-based healthcare? 8
Learning by portfolio 9
Electronic databases 11
Stage 3: Frame your own question and search for the evidence 47
iv Contents
References 119
Index 123
About the authors
Ruth Chambers has been a general practitioner for more than 20 years. She
is currently Director of GP Education at West Midlands Workforce Deanery
and Professor of Primary Care Development at Staffordshire University. Her
interest in clinical effectiveness and clinical audit grew from her three-year
spell as Chairman of Staffordshire Medical Audit Advisory Group in the 1990s.
Ruth has run several series of clinical effectiveness and clinical governance
workshops, teaching a mix of primary and community care health profes-
sionals clinical effectiveness skills in easy steps and an understanding of clinical
governance. The experiences of those workshops have informed this book.
David Rogers is the clinical effectiveness librarian for the Bedside Clinical
Guidelines Partnership. He has taught thousands of health professionals how
to seek for the evidence base for their practice over the years. David also
provides the evidence for clinical guidelines used by 15 hospital trusts across
the Midlands and beyond.
Acknowledgements
The book was originally based on the experiences from running two series of
four workshops, Clinical Effectiveness Made Easy, for primary and community
care practitioners and 20 workshops about Clinical Governance. We are grateful
to the participants of the workshops for contributing so many ideas and being
such enthusiastic health professionals. Irene Fenton, local lead healthcare
librarian, provided the inspiration and clear advice about undertaking literature
searches and other sources of evidence.
We are grateful to Nicky Macleod for her contribution about the meaning of
cost-effectiveness, and Dr Gill Wakley, who helped to devise and facilitate the
clinical governance workshops.
Ruth Chambers
Elizabeth Boath
David Rogers
February 2007
Introduction
Clinical effectiveness and
clinical governance are about
knowing what you should be
doing and being able to put that
knowledge into practice
1 How confident do you feel that you are capable of practising clinical
effectiveness to be able to:
ask a relevant question? Very Somewhat Not at all
undertake a search of the literature? Very Somewhat Not at all
find readily available evidence? Very Somewhat Not at all
weigh up available evidence? Very Somewhat Not at all
decide if changes in practice are warranted? Very Somewhat Not at all
make changes in practice as appropriate? Very Somewhat Not at all
2 Have you ever searched the literature yourself for an answer
to a question? Yes/No
If ‘Yes’:
which database(s) have you used?
Medline Cochrane OMNI Other (what?)
where did you search the literature?
Medical library At work At home Other (where?)
did you have any help in searching the literature?
None Healthcare librarian Friend/family Work colleague Other (who?)
3 Have you ever asked someone else to search the literature for you? Yes/No
If ‘Yes’:
who did the search for you?
why didn’t you do the search yourself?
Lack of time Lack of skill Lack of access Other reason
to databases
4 Can you complete the following list from your own knowledge, describing
the features of different types or levels of evidence in decreasing order of
robustness from very strong evidence to none at all?
Type Features
5 If you have previously searched for the evidence to answer a question you
had posed, what did you do with the result of your search? (Circle all that
apply.)
Discussed it with colleagues at work
Discussed it with friends or family
Made change(s) to an aspect of work
Decided against making any change(s) to any aspect of work
Other outcome – what?
6 To what extent is evidence-based healthcare central to your own practice?
(Circle all that apply.)
I have no idea whether my everyday practice is evidence-based most of the time
I assume that my everyday practice is evidence-based whenever possible, but
I’ve no evidence for that assumption
I ensure that my everyday practice is evidence-based by regularly comparing
my practice against published standards of best practice and making appropri-
ate changes
7 How many of these principles of good practice in clinical governance do you
generally include as part of your quality improvement work? (Circle all that
apply.)
I actively promote or participate in multidisciplinary working
I address national, local, organisational or professional priorities in my work
I try to achieve partnership working, e.g. between agencies, between manage-
ment/clinicians
I incorporate input from patients in my work (e.g. users, carers, the public) in
training, planning, monitoring or delivery of healthcare
I look for potential to achieve health gains in the way I organise my work
My everyday work is based on evidence-based practice, policy or management
I can demonstrate the standards of care or services that I or my team achieve
Clinical effectiveness and clinical governance made easy 5
Find out how to practise clinical effectiveness – don’t shut your eyes
to the changes going on around you.
Learning by portfolio
Portfolio-based learning has been promoted since the early 1990s as a style of
education that allows individuals to progress at their own pace. People can
adopt education relevant to their needs, and composing a portfolio allows
plenty of opportunities for reflection. Portfolio-based learning is not an easy
option16 compared to relatively passive types of learning such as listening to
lectures. It takes a great deal of effort to complete a successful portfolio built on
your past experiences and to progress through the stages of gathering and
processing new information, critical reflection, interpretation and application.
But it is worth it. The satisfaction that comes from completing a portfolio is as
much about being in control of your own education as acquiring new
knowledge, attitudes and/or skills.17,18
10 Clinical effectiveness and clinical governance made easy
Electronic databases
The Internet
The Internet is the largest computer network in the world to which almost any
type of computer can link. Most academic institutions are connected to the
Joint Academic Network (JANET) and its Internet service (JIPS); staff and
students can then access the Internet free on campus, or can dial up from home
via a modem for the cost of a local phone call. NHSNet is the equivalent for all
NHSstaff.
12 Clinical effectiveness and clinical governance made easy
Information can be extracted from the Internet or exchanged via the World
Wide Web (www) by electronic mail, newsgroups and file transfer protocol
(ftp). The World Wide Web is a system for providing access to a network of
interlinked documents and information services across the Internet. Docu-
ments can be stored on the Web as text, images, sound or video. The language
that the Web clients and servers use to communicate with each other is called
‘hypertext transfer protocol’ (http).
To use the World Wide Web you need software called a browser (or client) to
view www documents, such as Navigator or Microsoft Internet Explorer. The
latter is included with Windows, and the latest versions of both can be freely
downloaded from the Web. If you want to read more about what informatics
can do for you, read The Clinician’s Guide to Surviving IT.19
There is now a large number of Internet Service Providers (ISPs), with the
early ISPs such as AOL and CompuServe having been joined by others like
BTInternet and TescoNet. The wide availability of broadband access has made
using the Internet much more efficient and is rapidly superseding ‘dial up’.
Medline
Medline is produced by the National Library of Medicine in the United States
and is freely available to all (without a password) via the PubMed website:
www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed
Other ways of searching Medline on the Web include the Dialog interface for
all NHS staff * (ask your health library for a password or use the Athens self-
registration function), or the Ebsco interface for university students or staff.
Medline contains over 12 million citations dating from 1950 to the present,
from more than 4600 biomedical journals published in the United States and
70 other countries. Author abstracts are available for about 80% of the entries.
It covers the whole field of medicine, dentistry, veterinary medicine, medical
psychology, nursing, the healthcare system, and the pre-clinical sciences.
Coverage is worldwide, but most records are from English-language sources or
have English abstracts.
Cochrane Library
The Cochrane Library (www.nelh.nhs.uk/cochrane.asp) is considered to be
the single best source of reliable evidence about the effects of healthcare.20 The
Cochrane Library includes:
The Cochrane Database of Systematic Reviews (CDSR). These are struc-
tured, systematic reviews of controlled trials. Evidence is included or
* http://nhs.dialog.com/
Clinical effectiveness and clinical governance made easy 13
EMBASE
The Excerpta Medica database (EMBASE) is the largest competitor to Medline,
but has a European bias in contrast to its rival’s US bias. It contains over
7.5 million documents from 1974 to the present, indexed from over 4000
journals, and over 80% of entries have author abstracts. The overlap of coverage
with Medline is around 40%, so a search on EMBASE will often recover papers
not found on Medline. EMBASE has a similar subject coverage to Medline, but
is stronger on pharmacology and therapeutics. Unlike Medline, which enjoys
state subsidisation, EMBASE is produced commercially by the Dutch company
Elsevier, and has consequently been too expensive in the past for all but the
biggest of libraries to provide. However, EMBASE is now available as part of the
NHSCore Content via Dialog (see your health library for a password).
CINAHL
The Cumulative Index to Nursing and Allied Health Literature (CINAHL)
database, compiled by CINAHL Information Systems in the USA, is a compre-
hensive database of more than 1200 English language journals from 1982 to
14 Clinical effectiveness and clinical governance made easy
the present. Some foreign language material has been included since 1994.
CINAHL covers all aspects of nursing and allied health disciplines, such as
health education, occupational therapy, physical therapy, emergency services,
and social services and healthcare. Selected journals are also indexed in the
areas of consumer health, biomedicine and health sciences librarianship. The
database also provides access to healthcare books, nursing dissertations,
selected conference proceedings, standards of professional practice, educational
software and audio-visual materials in nursing. CINAHL has more than 7000
records with full text and 1200 records with images. Approximately 70% of
CINAHL headings also appear in Medline. CINAHL supplements these head-
ings with 4000+ terms designed specifically for nursing and allied health
disciplines. For more information, see the following website: www.cinahl.com
Several studies have compared Medline and CINAHL. These revealed that
while Medline assigns more index terms to each article, CINAHL uses index
terms that are more focused on nursing and therapy topics.21 Another study
revealed that CINAHL was preferred by nursing students as it gave a higher
number of relevant articles, while a further study found that both databases
were relevant for allied health professionals (AHPs).22,23 The authors
concluded that, in order to ensure a comprehensive search, both Medline
and CINAHL should be used. CINAHL is available via Dialog (see your health
library for a password).
search tool for accessing literature citations and linking to full-text journals
at websites of participating publishers. It provides access to over 12 000 000
citations in Medline, PreMedline (updated daily, providing basic citation
information and abstracts before the citation is indexed and added to
Medline), NLM Gateway and other related databases, with links to partici-
pating online journals and textbooks. The NLM Gateway also gives access
to OldMedline, which indexes journal articles from 1950 to 1965. Although
searching PubMed is free, user registration, a subscription fee, or fee at the
point of use may be required to access the full text of articles in some
journals. It is available at www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=
pubmed
The TRIP+ database is a one-stop search engine for evidence-based ma-
terial on the Internet and is available only on subscription, although your
higher education institution may have Athens access. www.update-
software.com/scripts/clibng/html/tripusernamelogon.htm
Useful software
Mentor Plus27 is an electronic medical knowledge clinical support system
originally developed by Oxford University Press with EMIS (Egton Medical
Information Systems Ltd). It has information about more than 2000 diseases
cross-referenced with about 26 000 commonly used medical terms. The
programme comes up with a differential diagnosis for a set of symptoms, signs
and test results, suggesting appropriate management plans which are a mix of
evidence-based medicine and best practice. EMIS is now offering an updated
version, ‘Web Mentor Libary’ as a subscription service costing at present £74
plus VAT per annum.
Electronic journals
The situation regarding access to the full text of online journals is complicated
and ever-changing. Ask your healthcare librarian for details. Some of the
websites show the full contents of the journal, others do not carry the full text of
all original articles.
18 Clinical effectiveness and clinical governance made easy
British Medical Journal www.bmj.com (is now freely available for the
current issue only, although your institution may have Athens access to
full text).
As part of the NHS Core Content package, Proquest and some other agents
provide access to over 1200 full-text journals with links to Dialog database
search results. Ask your health library for an Athens password to use this
service.
Higher education users will have access to a different package of electronic
journals, usually needing an Athens password. Your university or college
library can provide details.
‘The greatest obstacle to discovering the truth is being convinced that you
already know it.’
Stage 1
Asking the right question28
Although you may be burning to ask your question, when you actually try to
set it down on paper, you may find that the exercise is more difficult than you
think.
Questions have to be phrased in a very specific way to obtain meaningful
responses in any context. This applies to asking other people what they think
about a topic as much as for searching the literature for the best evidence.
The best clinical questions relate to queries arising from your own patients
during the course of your work rather than being hypothetical questions.
Relevant work-based questions should motivate you to seek the evidence and
make change(s). Before you go to a lot of trouble to find answers or solutions to
your questions, ask around at work and find out if anyone else is concerned
about the same question or problem, already has the answer(s), or knows
where to find them.
The question should be:
simple
specific
realistic
important
capable of being answered
agreed and owned by those who will be involved in any changes resulting
implementable
about a topic where change will be possible.
Think about how to construct your clinical question by considering:
what the question is about. For example, is the question about an individual
or group of patients? What are the patient characteristics you are interested
in, such as age or gender? Is it a clinical dilemma or a resource problem?
the setting. For example, is it specific to primary, secondary or community
care, rural or urban locations?
the type of intervention and whether it is being compared with current
practice or another intervention. For example, are you interested in differ-
ent treatments, causes, prognostic factors or risks, compared with current
practice or no treatment?
20 Clinical effectiveness and clinical governance made easy
‘I have finally made up my mind but the decision was by no means unanimous.’
Author: Anonymous
Language: English
BOSTON:
CROSBY & AINSWORTH.
NEW YORK: OLIVER S. FELT.
1866.
STORIES.
The fact was, Edwin was getting tired of his rabbit; he, however,
bought it a few oats, and gave it a little hay. He went out for a few
mornings and gathered a little clover, but in less than a week this
was thought to be a great deal of trouble; besides which, the rabbit
seemed lame, and did not look so pretty as it did at first.
At last Edwin quite forgot his rabbit for two days, and when he
went to look at it he was quite surprised to find it lying on its side. He
called, bunny, bunny. The poor thing looked at him, and seemed
pleased to see him, for its long ears moved as if it was.
Edwin took it up; it seemed to have lost the use of its hind legs; it
squeaked when it was touched; and so the little boy laid it down
again. He felt it all over—it was very thin, and seemed half starved.
Edwin now ran and got a saucer full of oats, and placed it beside
the poor thing; he also ran to the next field, and plucked some nice
sow thistle, and gave it to eat. Bunny looked grateful, and tried to
eat, but could not.
Edwin, in placing his hand down by its side, felt the beatings of its
heart; it went beat, beat, beat—throb, throb, throb, quicker than a
watch; and every now and then its head twitched, and the skin of its
jaw drew up, as if it were in great pain.
And yet the poor animal seemed glad to have some one by its
side, and rubbed its nose against Edwin’s hand; and then it panted
again, and its eyes grew dim; it was dying; Edwin now began to cry.
“Oh! my poor dear, dear, dear, bunny,” said he, “what shall I do to
make you well?—oh! what would I give? Oh! I have killed you, for I
know I have. Oh! my poor, dear bunny—let me kiss you, dear
bunny”—Here the little fellow stooped down to kiss the rabbit. Just at
that moment it gave a struggle—in the next it was dead.
Edwin’s eyes were full of tears, and when he could see through
them, and found out what had happened, he broke out into loud sobs
and cries, till he roused the whole house. “Oh! my dear rabbit—oh! I
have killed my rabbit—oh! what shall I do?” he uttered, in deepest
grief.
“Ay,” said his mama, who was called to the spot by his outcries, “I
feared it would be thus:—who would think a house-bred rabbit could
live in a damp pig-sty? The poor thing has been destroyed by
neglect.”
“Oh, yes, dear mama, do not scold me; I know I have been very
naughty. Oh, I do love my dear rabbit; I love it more now it is dead
than I did when it was alive; but is it really dead, mama! no, is it? it is
quite warm, and may get well again,—say it will, there’s a dear, dear
mother,” and then he cried again.
The rabbit was, however, dead; and had caught its death in the
way Edwin’s mama supposed, by being ill fed and kept in a damp
place, by thoughtless, if not cruel, neglect.
Edwin was overcome with grief,—but it was now too late, sad was
that night to him, for something told him that he had been cruel to
that he had promised to love. He got no sleep; and early in the
morning he arose, and went to the place where his pet was laid.
He wept all the next day; and, in the evening, he dug a grave in his
own little garden, close by the side of a young rose tree. Then he
wrapped the body in some nice hay, and laid it in its narrow cell, and
placed rose leaves upon it, and covered it gently with the earth; and
his heart was like to burst when he heaped the mound upon it,—and
he was forced to pause in his task by the full gushing of his tears.
“My child,” said his mama, who watched him at his sorrowful task,
“if you had taken half the trouble for bunny, when alive, as you do
now he is dead, he would have been alive now.”
“Yes, yes, dear mama,—I know—I know; but do tell me, pray do—
will not rabbits go to heaven? Is there not some place where they
can be happy? I hope my poor bunny may!” and here the little fellow
sobbed again.
“Give me a kiss, my dear boy,” said his mama; come leave this
spot: and so she gently led him away from the rabbit’s grave.
JULIA MARTIN.
N many of the little coves and bays on the coast of
Cornwall, small villages may be found—the dwellings of
fishermen, their wives, and families. Here, perhaps, they
have lived from the time they were born, without a
thought or a wish, as far as the land is concerned,
beyond the narrow place in which they dwell. The sea is the great
object of their cares, for it contains the means by which they live. By
the fish which they catch in it, they are provided with meat, drink, and
lodging: and too often is the sea their grave. The poor men lead a
hard and anxious life in their fishing pursuits; and are often tempted
to risk their lives, rather than give up a chance, when a favorable
shoal of fish may be expected. The women mostly spend their time
in making and mending nets, and drying and salting the fish. Even
the children may be always found employed about fish in some way
or other. The very young make playthings of the bones; those about
ten or eleven assist their mothers in curing fish; and all, both old and
young, feed, with a relish never lost, on the finny tribe. It is a pretty
sight, on a fine sunny day, to see the seine, or net, drawn in on the
white pebbly beach: it contains, perhaps, many hundreds of fishes,
tinted with all the colors of the rainbow. The various families to whom
the net belongs crowd down to the shore for their share of the fish;
for, as the net costs a great deal of money, the price is divided,
perhaps, between half a dozen owners. During the winter season,
should there have been any failure in the fishing, great hardships are
sometimes felt by these poor people. The stock of salt fish is done;
potatoes are dear, and money to buy bread is but scarce. The
patience and self-denial shown under such privations is truly to be
admired, and might furnish a useful lesson to those whom it had
pleased God to provide, at all seasons, with every thing that can
make life pleasant; and who are too apt to complain if some of the
lesser means of their enjoyment are cut off by a hard winter season.
THE FISHERMEN.
Rosecreay, one of the fishing villages we have been describing,
was fortunate, during a very severe winter, in having near it a very
charitable lady, who had taken a house which for many years had
been without an inmate.
Why she remained in a cold and bleak spot, so far from London,
from whence she came, her friends often wondered; and her
daughter Julia, when she heard the wind coming in great gusts up
the valley, or the rain beating against the windows, as if it insisted on
coming in, would wish she was back again in the pretty house at
Kensington. Mrs. Martin was not poor, but she was not rich, and she
had taken the old house for three years, because the rent was very
low; her own house in town she had let, and the change was made
that her only son, Frederic, might study as a painter. How many
mothers thus deny themselves comforts, that they may save money
for those dearer to them than their own lives! How few meet with any
reward for their self-denial! Mrs. Martin was constant in her visits to
the families of the fishermen; gave them tracts to read; made clothes
for the poor children; and was always ready, in time of illness, with
medicine for the sick, and soup for those getting better. She also
tried to teach them cleaner habits; but in this she failed. Julia soon
got tired of going with her mother to see people who persisted in
having such bad smells in and about their houses, wondering, at the
same time, that, with water so near, the village was not kept cleaner;
to which an old woman would sometimes reply, that fish never smell
ill to them. One stormy day in January, Mrs. Martin and Julia sat at
the window watching the huge waves that came tumbling in, with, as
Julia said, “great white caps on their heads.” The fine weather of
yesterday, said Mrs. Martin, I hear, has tempted poor John Penman
to go out fishing, in spite of his having hardly got rid of the fever he
has so long had. I am afraid that as he knew that Frederic is coming
we should like some fish to-day. The weather changed so suddenly
in the night, that I feel quite anxious lest he should have been lost.
Mrs. Martin’s fears were too well founded, for John Penman, his
eldest son, and another lad, never saw their homes again: the boat
had been lost during the heavy gale, and all on board had perished.
How dreadful! said Julia. I wish we did not live where we were
always hearing and seeing such disagreeable things. We must not,
my dear Julia, said her mother, indulge in such selfish feelings; let us
rather think what we can do for the poor widow and her orphans,
whether it is disagreeable or not. The next morning, though it was
still stormy, Mrs. Martin set out for the cottage of Mrs. Penman; and
as Julia thought it was too cold to venture out, she was spared the
sad scene that was seen by Mrs. Martin. The children were crying
round the bed of their poor mother, where she lay in too much grief
to attend to the kindness of the neighbors, who crowded round trying
to comfort her.
The room was small and dirty, with but little furniture in it; but
strange to say, on one side of it hung an old circular painting, and
though it was nearly black with smoke, Mrs. Martin could see it was
no common picture. With the hope that it might prove of some use to
the poor woman, she got the eldest boy to carry it to her house,
sending back by him a basket laden with food for his desolate home.
Frederic had arrived in due time the night before, and his mother
now begged him to look at the old painting. Although he had not long
been an artist, he at once saw that it had been painted by a skilful
hand. While cleaning it from the smoke and dirt, they found the name
of the painter and of the lady on the canvas. On inquiry, they also
found that John Penman’s father had saved the picture from a great
house, which had been burnt to the ground many years ago. Mrs.
Martin wrote to the family to whom the painting had once belonged,
and they were glad to pay the poor woman, to her great surprise and
joy, a handsome sum of money for it. She was then able to buy a
share in a net, which her husband had always been too poor to do,
and by it was enabled to bring up her family in the humble way to
which they had always been accustomed.
Ah! mother, said Julia, what good you have been able to do from
always thinking of other people rather than yourself. I will never
grumble again at the smells of the fishing village, but try, if I can, to
be as useful there as you have been; and Julia, in spite of the cold
and bleak winter, well kept her promise.
SUMMER
THE HAYMAKERS.
HE haymakers are working blithely, tossing about the
grass, and talking and laughing right merrily. This is a
holiday, both for old and young. Many who are
employed in manufactures, with their wives and
children, obtain leave to work in the fields when hands
are scarce; and doing so seems like a new life to them. You may see
at the further end, hillocks of grass thrown up in long rows; the
haymakers call them wind-cocks; they are piled light and high, that
the wind may blow through them; but in this part of the field people
are tossing the hay about. Gray-headed old men are here, aged
women, and children, seemingly without number. Their parents are
hard at work and very glad are they to put the “wee things” in safe
keeping among the old folks, who yet can help a little. Look at those
girls and boys at play—see how they pelt one another with the hay,
and roll each other over upon the grass—these are happy days. See
those youngsters, scarcely able to totter, how they tumble on the
sweet, fresh grass; while those who have strength to handle the rake
mimic the labors of their parents, and draw tiny loads along the
greensward. Meanwhile the hay is thrown about, and with each
returning day comes the same pleasant labor, till the creaking of a
wagon, lumbering up the hollow-road from the old farm-house, half
way down the hill, gives the signal, which tells that the haymaking
season is about to close. A short time elapses, and the creak of the
heavy laden wagon is heard ringing over the stones. It comes up
again for another load, then lumbers back to the old farm, where
laborers are busily employed in placing the hay upon a strong
foundation of wattled boughs. Some tread down the hay; others
throw it up from out the wagon; till at length loud huzzas, that wake
up all the neighboring echoes, announce that all the hay-stacks are
completed.