Professional Documents
Culture Documents
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T ) ( cyto-toxic T cells . TC
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T NKT
NK . CD1d
T
TC
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DNA
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DNA DNA
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T )-(Th T
T MHC .2
T) .(Helper T cells, +CD4
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MHC 2
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()- Th1
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. Il-2(2)
Tc
B
. IgG2a
()- Th2 ,
,,
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-Il-2, Il-5, Il-6 iL10 TGF,
B
Antigen presentation stimulates T \IgA, IgE, IgM .IgG-1
.
"cells to become either "cytotoxic
CD8+ cells or "helper" CD4+ cells
MHC II T.
MHC - -
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MHC , ,
. T CD4 MHC-
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An antibody is made up of two heavy
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The variable region,which differs from one
antibody to the next, allows an antibody to
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IL-4 . IL-6
The T lymphocyte activation pathway. T cells contribute to immune defenses in two
major ways: some direct and regulate immune responses; others directly attack infected
or cancerous cells.
The B lymphocyte activation pathway. B cells produce antibodies that identify and
neutralize foreign objects like bacteria and viruses
) (,
.T
T Tc
T (Helper)Th: 2
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T ) (Ts suppressor
T
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Th Ts
Th
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T B
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TC
TC
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TC
) ( Apoptosis
DNA
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Killer T cellsalso called cytotoxic T
attack other cells carrying certain
foreign or abnormal molecules on their
surfaces
" " ).( vaccination-
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-
1978
,
.
,
, 1911 P.Rous
.
1978
, HTLV(Human T-cell
) , Lymphotoropic Virus
.
HIV (human
) immunodeficienoy virus ,
"" T
T
: , T4
.
HTLV
:
- )Aquired -
.(Immunodeficiency Syndrome Aids
T ) Adult T cell Leukemia -
( ATL
.
T
.
T
,
,
.
1978 ATL
, HTLVI 1983
HTLV . HIV
)(RNA ,
) (
.
RNA RNA
,
RNA
, RNA
. reverse transcription
3 9000 -5000
) (%70 - %60
20000 3 4000
.
12-6 / 3
chemotaxis :
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T T
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B . Tk
Tk
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Ts
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6
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110
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.