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principales of common paediatric

tumors:
- Neuphroblastoma
- Neuroblastoma

By
Dr. LUC KINYOMA

1
Introduction
Nephroblastoma
isatypeofcancerwhichdevelopsinthekidneys.
ThiscancerisalsocalledWilmstumor,andisthe
most
commontypeofkidneycancertodevelopinchildren.
Inthe1950sand1960s,mostchildrenwith
nephroblastomahadaverypoorprognosis,but
treatmentforthecancerhasadvancedsignificantlyin
theinterveningdecades.
ThesuccessrateforWilmstumortreatmentisnow
approximately90%,largelyduetothepracticeof
combiningsurgerywithradiotherapyorchemotherapy
Wilms'tumorwasnamedafterDR.MaxWilms,who
firstdescribedit.It'satypeofkidneycancer.
It'sthoughttocomefromveryspecialisedcellsinthe
embryoknownasmetanephricblastema
Thesecellsareinvolvedinthedevelopmentofthe
child'skidneyswhilethey'reinthewomb.
Thesecellsusuallydisappearatbirth,butinmany
childrenwithWilms'tumor,cellscallednephrogenic
restscanstillbefound

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