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  • Sclerodermie PCL

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    Serban Elena
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    This patient has signs and symptoms of systemic sclerosis including: - Raynaud's phenomenon seen on nailfold capillaroscopy - Skin thickening and loss of sweat glands and hair follicles on biopsy - Gastrointestinal involvement with esophageal dysmotility and diverticuli - Pulmonary fibrosis seen on radiography and restrictive lung disease - Renal impairment and rapidly progressive renal failure - Hepatic involvement with autoimmune hepatitis and primary biliary cirrhosis - Inflammation seen throughout the body including the lungs, liver and kidneys.

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    Original Title

    Sclerodermie Pcl

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    This patient has signs and symptoms of systemic sclerosis including: - Raynaud's phenomenon seen on nailfold capillaroscopy - Skin thickening and loss of sweat glands and hair follicles on biopsy - Gastrointestinal involvement with esophageal dysmotility and diverticuli - Pulmonary fibrosis seen on radiography and restrictive lung disease - Renal impairment and rapidly progressive renal failure - Hepatic involvement with autoimmune hepatitis and primary biliary cirrhosis - Inflammation seen throughout the body including the lungs, liver and kidneys.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    12 views17 pages

    Sclerodermie PCL

    Uploaded by

    Serban Elena
    This patient has signs and symptoms of systemic sclerosis including: - Raynaud's phenomenon seen on nailfold capillaroscopy - Skin thickening and loss of sweat glands and hair follicles on biopsy - Gastrointestinal involvement with esophageal dysmotility and diverticuli - Pulmonary fibrosis seen on radiography and restrictive lung disease - Renal impairment and rapidly progressive renal failure - Hepatic involvement with autoimmune hepatitis and primary biliary cirrhosis - Inflammation seen throughout the body including the lungs, liver and kidneys.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    of 17

    Brindusa Cimpoca

    Seria 3, gr.19
    Hemoleucograma
    Anemie polietiologie :
    - anemie cronic simpl- normocroma, normocitara
    - hemoliza mecanic (microangiopatic)
    - hemoliza autoimun
    - hemoragic microcitara, hipocroma prin HD stomac
    watermelon, esofagita cronica

    VSH, proteina C reactiva, fibrinogen crescute


    Hipergamaglobulinemie
    Crioglobulinemie
    Transaminaze crescute in hepatita autoimuna
    Bilirubina crescuta in ciroza biliara primitiva
    1. Piele
    Biopsie:
    -dispar glandele sudoripare
    - dispar foliculii pilosi
    -derm ingrosat, bogat in colagen,
    epiderm subtiat, arteriole fibrozate
    Calcinozis circumscripta
    Capilaroscopia
    periunghiala
    Radiografii: eroziuni oasoase, resorbtii
    oasoase terminale degete, radius, ulna, unghi
    mandibula
    Radiografie: esofag de sticla

    Endoscopie
    Afectare esofag distal: hipotonie, relaxare
    sfincteriana, BRGE, esofagita, eroziuni, sangerari,
    esofag Barret
    Atonie
    Tulburari de golire
    Ectazii vasculare antrale- watermelon
    Tranzit baritat
    Coloniscopie

    Diverticuli cu
    baza larga
    Biopsie:
    Hepatita autoimuna
    Ciroza biliara primitiva

    Distrugerea arhitecturii
    normale a ficatului si infiltrat
    limfocitar periductal
    Radiografie
    ->Fibroza interstitiala difuza, aspect de sticla mata
    -> pleurezii
    ->pneumotoax
    -> pneumonie

    CT -> hemoragia pulmonara

    DLCO restrictie

    Lavaj bronho-alveolar: celularitate bogata


    Neutrofile, eozinofile, limfocite CD8+

    Biopsie pulmonara risc de cancer


    Radiografie plaman
    Ecografie cord
    EKG
    -> HT pulmonara
    EKG -> tulburari de ritm, de conducere
    Ecografie
    -> pericardita
    Uree, Creatinina serica cresc rapid
    -> Insuficienta renala rapid profresiva
    Examenul urinei: sumar de urina, sediment
    unirar, biochimie

    7. Tiroida
    Ecografie ->fibroza

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