a) Name 3 morphological abnormalities in

red cells in this blood picture.

b) What is the condition?
a)Fragmented red cells
-Neutrophil leucocytosis (Increased number)
-Low platelets
b) DIC

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DIC- blood picture

Neutrophil leucocytosis

Fragmented red cells

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a)Identify A & B?
b)What is the condition?
c)What are the clinical features of above
condition?
6
a) A-Bite cells
B- Blister cells
b) G6PD deficiency
c)
1. Haemolysis due to oxidizing agents.
2. Neonatal jaundice.
3. Congenital non spherocytic
haemolytic anaemia
G6PD deficiency anaemia- blood picture

Bite cells

Blister cells

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a)What is the cell indicated by the arrow?
b)How did you identify?
c)State the most likely causes?
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a)Acanthocytosis
b)Red cells with irregular spikes
c)Liver disease
Renal disease
a) Write 3 features in the picture.
b) What is the diagnosis?
c) What is the chromosomal abnormality of
above condition?
13
a)High white cell count
-Increased number of neutrophils
-Increased number of myelocytes

b) Chronic myeloid leukaemia

c) Presence of Philadelphia chromosome

a) What is the condition?
b) How did you identify?
c) What are the clinical presentations?
a)Chronic lymphocytic leukaemia

b)
-Increased number of mature lymphocytes
-Smudge cells
-Size of a mature lymphocyte nucleus = size of
a normal red cell
-Mature lymphocytes have clumped chromatin
c)
BM Failure
 Anaemia (pallor, lethargy,dyspnoea)
 Neutropaenia(fever,malaise,infecions)
 Thrombocytopaenia (spontaneous
bruises,purpura,bleeding gums,menorragia)
Organ Infiltration
 Tender bones
 Lymphadenopathy
 Moderate splenomegaly
 Hepatomegaly
 meningeal Syndrome
 Testicular swelling
 Mediastinal compression
Chronic lymphocytic leukemia- blood picture

Smudge cell

Mature lymphocytes

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