Professional Documents
Culture Documents
Inheritance
INCOMPLETE DOMINANCE
-NEITHER ALLELE IS COMPLETELY DOMINANT
OVER THE OTHER
Red flower = RR
Pink flower = Rr
White flower = rr
Sample problem:
Type B
Type AB
Type O
Human Blood Genotypes and
Phenotypes
Phenotype Genotype(s)
•1.
•2.
•3.
•4.
Sample Problem #1:
Acid pH
Alkaline pH
• Epistasis
– Action of genes at one loci modify
expression genes at another loci
• Effects often complex
– Examples
• Normal expression of ABO blood type
depends on functional fucosyltransferase 1
– Recessive = no expression/attachment of
antigen to blood cell
• Other examples:
– Anthocynanin coloration in corn
– Coat color in Labrador dogs
Epistasis
One gene affects the expression of a
second gene
• Ee or EE deposition of melanin
• ee deposition of pigment blocked
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ee E_
No dark pigment in fur Dark pigment in fur
Yellow Lab
E_bb E_B_
eebb eeB_ Chocolate Lab Black Lab
Yellow fur; Yellow fur; Brown fur, Black fur,
brown nose, black nose, nose, lips, nose, lips,
lips, eye rims lips, eye rims eye rims eye rims
Pleiotropy
Pleiotropy refers to an allele which has
more than one effect on the phenotype.