Nucleus

Microtubules Microfilaments
Chromosomes
4 Pics 1 Word
Cell
Cell Cycle
• A cell must complete several important
task.
• To divide.
• Copy its genetic material (DNA).
• Physically split into two daughter cells.
Two main stages in the Cell Cycle-
INTERPHASE and MITOSIS
I. Interphase
• Refers to the period that follows one cell
division and precedes another.
• The cell does not divide: it merely grows.
• The chromosomes doubles or replicates itself
because the DNA molecule contained in the
chromosome produces an exact copy of itself.
The Interphase is divided into three
substages
1. Gap 1 or G1
• Refers to the primary growth phase of the
cell.
• The cell grow and increases in size.
• In this stage, proteins are synthesized and cell
organelles are produced.
2. Synthesis or S
• Is the period where chromosomes are
duplicated in the preparation for the next cell
division.
3. Gap 2 or G2
• It is called gap 2 since it fills the space
between DNA synthesis and the
beginning of mitosis.
II. Mitosis
- a type of cell division produces two
identical cells with the same number of
chromosomes.
Prophase
• The chromosomes appear condensed, and the
nuclear envelope is not apparent.
• At this stage, each chromosomes is made up of two
identical sister chromatids as a consequence of
replication of DNA during the S phase.
• (Chromosomes doubled to 92)
Metaphase
• The nuclear membrane has disappeared while the
highly coiled chromosomes align at the metaphase
plate.
• Spindle fibers are also formed.
• Each fibers binds to a protein kinetochore at the
centromere of each sister chromatid of the
chromosome.
• (Chromosomes align at the middle of the cell.)
Anaphase
• The paired centromeres of each chromosomes
separate towards the opposite poles of the cells as
they are pulled by the spindle fibers through their
kinetochore.
• (Separated chromosomes pulled apart.)
Telophase
• The chromosomes are now at the opposite poles of the
spindle.
• A new nuclear membrane forms around them while the
spindle fibers disappear.
• There is also cytokinesis or the division of the cytoplasm
to form two separate daughter cells immediately after
mitosis.
• (Microtubules disappear and cell division begins.)
• Cytokinesis involved formation of cleavage
furrow, which pinches off or divides the cell into
two.
Cytokinesis
• Two daughter cells formed and each with 46
chromosomes.
I. Identification
Direction: Read the question carefully. Choose your answer in the box.

1.__________, ___________ Give the two main stages of cell cycle?

2. In this stage of cell cycle the cell grows and increases in size?
3. Synthesis stage or S is where the DNA is replicated, how many hours this
stage takes?
4. It is a process of cell division the results in the production of two daughter
cells from a single parent cell?
Mitosis Gap 1 or G1 6-8 hours
Metaphase 4-6 hours Interphase

II. Enumeration
Direction: Enumerate the stages of Mitosis in order. (5-10)
Assignment
Direction: Draw the stages of Mitosis in short coupon
bond with color and write a short explanation on each
stage to be submitted next meeting.