Professional Documents
Culture Documents
Sex
Family Hx
Ethnic background
Modifiable
Smoking
High amounts of certain fats and
cholesterol in the blood
Physical inactivity
Stress (release of Catecholamine)
High amounts of sugar in the blood due to
insulin resistance or diabetes
When damage occurs, your body starts a healing
process. Excess fatty tissues release compounds
that promote this process. This healing causes
plaque to build up where the arteries are damaged.
The buildup of plaque in the coronary arteries
may start in childhood. Over time, plaque
can narrow or completely block some of your
coronary arteries. This reduces the flow of
oxygen-rich blood to your heart muscle.
Plaque also can crack, which causes blood
cells called platelets (PLATE-lets) to clump
together and form blood clots at the site of
the cracks. This narrows the arteries more
and worsens angina or causes a heart attack
Plaque
A Narrowing or obstruction of the coronary arteries
resulting from atherosclerosis. An accumulation of
fatty plaques made of lipids in the arteries
Causes a decrease perfusion of myocardial tissue
and inadequate myocardial oxygen supply
Atherosclerosis
Angina
I have chest pain!
Angina is chest pain or discomfort caused
when your heart muscle doesn't get enough
oxygen-rich blood.
CHF :- Congestive Heart Failure
Inability of the heart to do its job
It is the the condition in which heart’s
function as a pump is inadiquate to
meet body’s needs
Myocardial Infarction
It occurs when blood decreases or
stop to part of heartmuscle .
The most common symptoms is
chest pain & discomfort
Signs & Symptoms
Findings may be normal during asymptomatic
periods
Chest pain - due to lack of oxygen
Palpitations
Dyspnea
Syncope
Cough of hemoptysis
Excessive fatigue
Symptoms occurs when the coronary
artery is occluded to the point that
inadequate blood supply to the muscle
occurs causing ischemia.
Coronary artery narrowing is significant
if the lumen diameter of the left main
artery is reduced at least 50% or if any
major branch is reduced at least 75%
Lab test / Dx
ECG
a. When blood flow is reduced and
ischemia occurs, ST segment depression
or T-wave inversion is noted; the ST
segment returns to normal when the blood
flow returns.
Cardiac Catheterization
a. Provide the most definitive source for
diagnosis
b. Would show the presence of atherosclerotic
lesions
Blood lipid levels
c. Blood lipid levels may be elevated
d. Cholesterol-lowering medications may be
prescribed to reduce the development of
atherosclerotic plaques
Treatment