A Hypothetical Model for Biosensor Integrating Microcantilever on

the Parallel Plate Electrode Surface

Mohammad Salman Parvez, Md.Fazlay Rubby, Shanzida Kabir
Advisor: Dr. Nazmul Islam
Department of Electrical Engineering
College of Engineering and Computer Science

Abstract Bio-Sensor Prototype Conclusions & Future

Integration of MC & ACEO Description & Work
 Biosensors based on diffusion process Picture
are slow in nature Collection of individual component was done
 Integration of biosensing techniques Now working on integration of the system
with microfluidics & electro kinetics Detection Mechanism
have enabled potential improvement .
 AC electroosmosis (ACEO) is one of Bio particles will be trapped by ACEO in on
those techniques used to improve the the electrode surface and focused to the MC .
sensing and trapping of Bio-particles surface then the resonant frequency of MC
 In this presentation we are going to will be measured by LDV and add
introduce such a model which combines equations:
the effect of ACEO enhancement in a
Microcantilever type biosensor
 For this purpose parallel
microelectrodes can be used for ACEO
effect
 The resonant frequency of the
Microcantilevers can be measured by a
Laser Doppler Vibrometer (LDV).

Objective
 Introduce a model of Bio-sensor Prototype
 Sensing and Detection by Micro-Electro- Obtained Results
Mechanical-System (MEMS)
 Integrating AC electroosmosis (ACEO) to Put the results we obtained from AFM &
improve the sensing and trapping of Bio- show the picture of trapped particles by
particles ACEO
 To measure and count the bioparticles by Applications
measuring resonant frequency of Micro-
cantilever (MC)  Onsite Pathogen detection
 Point of care diagnosis
 Affordable healthcare
AC-Electro-osmosis  Remote low capital diagnosis lab
Here we used parallel electrodes for ACEO
mechanism with parallel electrode (picture)

Figure 1. Prototype of setup Figure 2. AC electroosmosis

for Particle trapping by ACEO
Micro-Cantilever
 The principle is to measure the change in
the frequency of vibrating element
 The mass increases due to binding of
chemicals, cells, particles & the oscillation
frequency of the device changes
 The resulting change can be measured
electrically and be used to determine the
additional mass
 Governing Equation:
;(
Where, =mass of cantilever
= spring constant
& = unloaded & loaded resonant
frequency respectively
mechanism Acknowledgments
If supported by PREM: The authors gratefully
acknowledge support received by NSF PREM
award under grant No. DMR-1523577: UTRGV-
UMN Partnership for Fostering Innovation by
Bridging Excellence in Research and Student
Success.
Figure 5. Cantilever A before Coating Additional Logo
(e.g. Research Center)
If desired
References
1. Jie Wu, Yuxing Ben , Hsueh-chia Chang

Figure 6. Cantilever A after coating.

Figure 3 Microscopic view of Figure 4 Mass Detection by

a Micro Cantilever Microcantilever