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CLASSIFICATION;
CONTENTS OF
CARTRIDGE +
FUNCTIONS;
IANB TECHNIQUE
DEFINITION
LA is defined as a loss of sensation in a circumscribed area
of the body caused by depression of excitation of nerves
endings or an inhibition of the conduction process in
peripheral nerves.
LOSS OF SENSATION WITHOUT LOSS OF
CONSCIOUSNESS.
Properties of LA
Should be non-irritating to tissue
Not cause any permanent alteration of nerve structure.
Time of onset should be short
Effective
Duration of action should be long
It should be either sterile or be capable of being sterilized by heat
without deterioration.
Systemic toxicity should be low.
Free from producing allergic reactions
It should be stable in solution and should readily undergo
biotransformation in the body.
MODE OF ACTION OF LA