toxemia and hyperthermia Toxemia Septicemia Bacteremia
Presence of Presence of Presence of
toxins in the large number of bacteria in the blood stream pathogens and blood stream either derived their toxins in for only from bacteria the blood transitory of body cells stream through period and do out the course not produce of disease and clinical signs produce clinical signs Etiology Septicemia
Primary Secondary
e.g. Anthrax, e.g. metritis,
Common Pasteurollosis, Occurs as a mastitis, salmomellosis, complication with some Listeriosis, Rift associated with arthritis, endocarditis, specific valley fever, African swine any supportive pneumonitis, diseases process with in fever, Bovine viral internal rupture diarrhea etc the body of abscess etc Pathogenesis Exotoxins and Endotoxins Toxemia and high fever
Endothelial damage and
hemorrhages into the tissues Interfere with coagulation system Intra vascular clotting or severe hemorrhages Death Clinical Signs
• Sub-mucosal and Sub-epidermal hemorrhages
• High elevation of body temperature (up to 106-108oF)
• Other signs are same as in toxemia and hyperthermia
• In chronic cases there may be cardiovascular or
respiratory failure Treatment • Same general recommendations may be applied as in toxemia • When body temp. reaches 106-108oF, consider it an emergency, attempt should be made to lower the body Temp. by cold applications