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Septicemia

• Presence of large number of pathogenic


microorganisms in the blood

• Disease state compounded of


toxemia and hyperthermia
Toxemia Septicemia Bacteremia

Presence of Presence of Presence of


toxins in the large number of bacteria in the
blood stream pathogens and blood stream
either derived their toxins in for only
from bacteria the blood transitory
of body cells stream through period and do
out the course not produce
of disease and clinical signs
produce clinical
signs
Etiology
Septicemia

Primary Secondary

e.g. Anthrax, e.g. metritis,


Common Pasteurollosis, Occurs as a
mastitis,
salmomellosis, complication
with some Listeriosis, Rift associated with
arthritis,
endocarditis,
specific valley fever,
African swine
any supportive
pneumonitis,
diseases process with in
fever, Bovine viral internal rupture
diarrhea etc the body
of abscess etc
Pathogenesis
Exotoxins and
Endotoxins
Toxemia and high fever

Endothelial damage and


hemorrhages into the tissues
Interfere with coagulation system
Intra vascular clotting or severe
hemorrhages
Death
Clinical Signs

• Sub-mucosal and Sub-epidermal hemorrhages

• High elevation of body temperature (up to 106-108oF)

• Other signs are same as in toxemia and hyperthermia

• In chronic cases there may be cardiovascular or


respiratory failure
Treatment
• Same general recommendations may be applied
as in toxemia
• When body temp. reaches 106-108oF, consider it an
emergency, attempt should be made to lower the body
Temp. by cold applications

• Antipyretics, antitoxins, broad spectrum antibiotics,


fluid and electrolytes, multivitamins, minerals,
amino acids, hemotonics etc are recommended
• Provide soft and nourishing feed to the animal

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