Endocrine system

Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Pituitary gland, monkey H&E (LP) This micrograph from a midline section through the brain and cranial floor illustrates the pituitary gland in situ. The pituitary sits in a bony
depression in the sphenoid bone called the sella turcica. The two maj...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Anterior pituitary (illustration (d) opposite) (a) H&E (HP) (b) Azan (HP) (c) Immunohistochemical method for GH (HP) (d) EM ×4270 Micrograph (a) is an H&E-stained
preparation of anterior pituitary and shows two main populations of cells, those wit...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Anterior pituitary (illustration (d) opposite) (a) H&E (HP) (b) Azan (HP) (c) Immunohistochemical method for GH (HP) (d) EM ×4270 Micrograph (a) is an H&E-stained
preparation of anterior pituitary and shows two main populations of cells, those wit...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Anterior pituitary (illustration (d) opposite) (a) H&E (HP) (b) Azan (HP) (c) Immunohistochemical method for GH (HP) (d) EM ×4270 Micrograph (a) is an H&E-stained
preparation of anterior pituitary and shows two main populations of cells, those wit...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Posterior pituitary (a) H&E (MP) (b) Immunohistochemical method for synaptophysin (HP) The posterior pituitary is largely composed of the non-myelinated axons of
specialised neurones which have considerable neurosecretory activity. The cell bodies...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Posterior pituitary (a) H&E (MP) (b) Immunohistochemical method for synaptophysin (HP) The posterior pituitary is largely composed of the non-myelinated axons of
specialised neurones which have considerable neurosecretory activity. The cell bodies...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Thyroid gland (a) H&E (LP) (b) Immunohistochemical method for CD34 The functional units of the thyroid gland are the thyroid folliclesF, spheroidal structures composed
of a single layer of cuboidal epithelial cells, bounded by a basement membrane ...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Thyroid follicle (a) Inactive, H&E (HP) (b) Active, H&E (HP) Thyroid follicles store thyroglobulin, an iodinated glycoprotein, the storage form of thyroxine (T 4) and tri-
iodothyronine (T 3). The follicles are lined by epithelial cells which are i...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Thyroid follicle (a) Inactive, H&E (HP) (b) Active, H&E (HP) Thyroid follicles store thyroglobulin, an iodinated glycoprotein, the storage form of thyroxine (T 4) and tri-
iodothyronine (T 3). The follicles are lined by epithelial cells which are i...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Thyroid C cell H&E (HP) A second type of endocrine cell with the ultrastructural characteristics of neuroendocrine cells, the C cell or parafollicular cellC, is found in the
thyroid gland as individual scattered cells in the follicle lining or as ...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Thyroid follicle, rat EM ×6800 This micrograph demonstrates a thyroid follicle composed of cuboidal follicular cells F surrounding a lumen containing the homogeneous
colloid, thyroglobulin Co. A basement membrane BM delineates the follicle. Two po...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Parathyroid gland H&E (LP) This micrograph shows a parathyroid gland PT, embedded under the capsule of a thyroid gland T. Some parathyroids are actually found
embedded in the thyroid tissue proper. The thin fibrous capsule of the parathyroid gland...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Parathyroid gland (a) H&E (MP) (b) H&E (HP) Micrograph (a) is a medium-power view of normal adult parathyroid, showing the glandular elements G intermixed with
adipose tissue A, which begins to accumulate after puberty and makes up 25% to 40% of t...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Parathyroid gland (a) H&E (MP) (b) H&E (HP) Micrograph (a) is a medium-power view of normal adult parathyroid, showing the glandular elements G intermixed with
adipose tissue A, which begins to accumulate after puberty and makes up 25% to 40% of t...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Adrenal gland (a) Azan (LP) (b) Azan (LP) At low magnification, the adrenal gland is seen to be divided into an outer cortex C and a pale-stained inner medulla M. A dense
fibrous tissue capsule Cap, stained blue in this preparation, invests the gl...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Adrenal gland (a) Azan (LP) (b) Azan (LP) At low magnification, the adrenal gland is seen to be divided into an outer cortex C and a pale-stained inner medulla M. A dense
fibrous tissue capsule Cap, stained blue in this preparation, invests the gl...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Adrenal cortex, zona glomerulosa Azan (MP) The zona glomerulosa G is composed of cells arranged in irregular ovoid clusters separated by delicate fibrous trabeculae T,
which are continuous with the fibrocollagenous capsule Cap; both the trabeculae...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Adrenal cortex, zona fasciculata Azan (MP) The zona fasciculata is the middle and broadest of the three cortical zones. It consists of narrow columns and cords of cells,
often only one cell thick, separated by fine strands of collagen and wide-bor...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Steroid-secreting cell (a) EM ×8500 (b) EM ×110 500 These micrographs illustrate the typical ultrastructural features of steroid-secreting cells, which are seen not only in
the cells of the adrenal cortex but also in the steroid-secreting cells of...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Steroid-secreting cell (a) EM ×8500 (b) EM ×110 500 These micrographs illustrate the typical ultrastructural features of steroid-secreting cells, which are seen not only in
the cells of the adrenal cortex but also in the steroid-secreting cells of...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Adrenal medulla (a) H&E (MP) (b) Chrome salt fixation, H&E (MP) The adrenal medulla secretes the amines adrenaline ( epinephrine) and noradrenaline ( norepinephrine)
under the control of the sympathetic nervous system. When stained with the standa...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Adrenal medulla (a) H&E (MP) (b) Chrome salt fixation, H&E (MP) The adrenal medulla secretes the amines adrenaline ( epinephrine) and noradrenaline ( norepinephrine)
under the control of the sympathetic nervous system. When stained with the standa...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Islet of Langerhans H&E (HP) The islets of Langerhans are composed of groups of up to 3000 secretory cells supported by a fine collagenous network containing
numerous fenestrated capillaries. A delicate capsule surrounds each islet. The endocrine ...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Blood supply of the endocrine pancreas Carmine perfused/haematoxylin (MP) This specimen was perfused with a red dye before fixation to demonstrate the rich blood
supply of the pancreatic islets. Each islet is supplied by as many as three arteriole...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine system
Young, Barbara, BSc Med Sci (Hons), PhD, MB BChir, MRCP, FRCPA, Wheater's Functional Histology, 17, 318-336

Islet of Langerhans (a) Immunohistochemical stain for insulin (MP) (b) Immunohistochemical stain for glucagon (HP) In the past, empirical staining methods were used to
demonstrate the different cell types in the islets of Langerhans. These have no...

Copyright © 2014 Copyright © 2014, 2006, 2000, 1993, 1987, 1979 by Churchill Livingstone, an imprint of Elsevier Ltd.
Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

Light micrograph of the pituitary gland displaying chromophobes (C), acidophils (A), and basophils (B). (×470)

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

Light and electron micrograph of mouse adenohypophysis (×4000). Observe the mammotropes (cells 3, 6–9, 12–15) and somatotropes (cells 2, 5, 11) and note the
secretory granules of these cells. From Yamaji A, Sasaki F, Iwama Y, Yamauchi S. Mammotrop...

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

This is a high magnification of the colloid-containing thyroid follicle and its surrounding connective tissue. Note the follicular cells (FC) that manufacture the colloid, as well
as the thyroid hormones present in the colloid. Also, observe the l...

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

Electron micrograph of a thyroid follicular cell bordering the colloid (black area, upper left-hand corner) (×10700). From Mestdagh C, Many MC, Haalpern S, et al.
Correlated autoradiographic and ion-microscopic study of the role of iodine in the f...

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

Schematic diagram of the synthesis and iodination of thyroglobulin (A) and release of thyroid hormone (B).

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

Low magnification of the suprarenal gland displaying its dense irregular collagenous capsule (Ca), the cortex (Co) that envelopes the medulla (Me), and the blood vessels
of the medulla (BV). (×56)

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

This medium-power magnification of the suprarenal gland cortex displays its capsule (Ca) and zona glomerulosa (ZG), along with the outer portion of the zona fasciculata
(ZF) with its slender amount of connective tissue and occasional connective ti...

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

This low-magnification photomicrograph displays the inner layers of the suprarenal cortex. Note that in the inner portion of the zona fasciculata (ZF), the parenchymal cells
are referred to as spongiocytes (Sp) because of the empty spaces left aft...

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

Light micrograph of the medulla of the suprarenal gland. Note the chromaffin cells (CC) whose nucleus (N) houses a single nucleolus (n). Observe the rich arterial supply
and venous drainage (V) of the suprarenal medulla (×270).

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

Electron micrograph of baboon adrenal medulla (×14,000). The different osmiophilic densities of the vesicles may be a reflection of their maturational phases. ER,
Endoplasmic reticulum; H, high-electron-density vesicle; L, low-electron-density ves...

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

Pineal gland. The large, dark-staining structures are brain sand (BS) scattered among the pinealocytes (Pi). Neuroglial cells are present but difficult to distinguish at this
magnification. (×132)

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

A medium magnification of the pineal gland displays the connective tissue trabeculae (T) that subdivide the gland into lobules (Lo) and convey vascular and nerve supply
to the pinealocytes (Pi). Note that the nuclei of the neuroglia (Ng) are small...

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Endocrine System
Gartner, Leslie P., PhD, Textbook of Histology, 13, 305-332.e2

This photomicrograph of the thyroid gland is from an individual with Hashimoto disease, an autoimmune disease in which the individual develops autoantibodies against
one’s own thyroid gland, destroying the thyroid follicles (A). The gland becomes ...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Regional Distribution of Anterior Pituitary Cells. A horizontal cross-section of the distal lobe of the pituitary. The lateral wings contain mainly somatotrophs, which secrete
GH, whereas corticotrophs, which secrete ACTH, β-lipotropin, α-MSH and ...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Traditional Methods for Demonstrating Cells of the Anterior Pituitary. Traditionally, cells of the anterior pituitary have been classified into three types: acidophils (cytoplasm
staining with acidic dyes), basophils (cytoplasm staining with basic...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Ultrastructure of Anterior Pituitary Cells. Electron micrograph of anterior pituitary cells showing their numerous hormone-containing dense-core granules (G).

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Posterior Pituitary. The posterior pituitary is composed of axons which originate from cells in the hypothalamus and possess numerous neurosecretory granules containing
either oxytocin or vasopressin, together with a carrier protein termed ‘neurop...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Hypothalamic Control of Anterior Pituitary Hormone Production. Hypothalamic neurons secrete releasing/inhibiting factors in response to chemoreceptive and neural
inputs. These hormones diffuse into capillaries at the median eminence and are carrie...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Thyroid. (a) Micrograph showing normal human thyroid composed of variable-sized follicles (F) filled with pink-staining thyroid colloid. In this illustration the thyroid follicles
are in a storage phase, so the lining epithelium (E) is cuboidal or...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Thyroid. (a) Micrograph showing normal human thyroid composed of variable-sized follicles (F) filled with pink-staining thyroid colloid. In this illustration the thyroid follicles
are in a storage phase, so the lining epithelium (E) is cuboidal or...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Thyroid Colloid. (a) The formation of thyroid hormone requires the interaction of thyroglobulin and iodine. Thyroglobulin is produced by the thyroid epithelial cells, its protein
component being synthesized in the rough endoplasmic reticulum and t...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Parathyroid. (a) Micrograph showing a child's parathyroid gland (P) closely associated with lymphoid tissue (L). The gland is almost entirely composed of endocrine cells
separated by fibrocollagenous septa (S) rich in blood vessels. With increasin...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Adrenal Cortex. (a) Low-power micrograph showing adrenal cortex (C) and medulla (M). Three distinct zones can be seen in the cortex, the zona glomerulosa (ZG), zona
fasciculata (ZF) and zona reticularis (ZR). (b) Micrograph showing the adrenal cor...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Adrenal Cortex. (a) Low-power micrograph showing adrenal cortex (C) and medulla (M). Three distinct zones can be seen in the cortex, the zona glomerulosa (ZG), zona
fasciculata (ZF) and zona reticularis (ZR). (b) Micrograph showing the adrenal cor...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Zona Glomerulosa. The zona glomerulosa is composed of small compact cells (C) arranged in clumps and separated by stroma composed largely of thin-walled
capillaries. The cells contain scanty lipid droplets associated with well-developed smooth end...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Zona Fasciculata. (a) These cells are arranged in vertical columns, which are usually two to three cells wide, the columns being separated by capillaries (Cap). (b)
Ultrastructurally, the cells have prominent rough endoplasmic reticulum, character...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Zona Fasciculata. (a) These cells are arranged in vertical columns, which are usually two to three cells wide, the columns being separated by capillaries (Cap). (b)
Ultrastructurally, the cells have prominent rough endoplasmic reticulum, character...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Adrenal Medulla. (a) Micro­graph of adrenal medullary cells show­ing their large nuclei and finely granular cytoplasm. (b) Electron micrograph showing large dense-core
granules corresponding to norepinephrine (noradrenaline) (N) and epinephrine (a...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Adrenal Medulla. (a) Micro­graph of adrenal medullary cells show­ing their large nuclei and finely granular cytoplasm. (b) Electron micrograph showing large dense-core
granules corresponding to norepinephrine (noradrenaline) (N) and epinephrine (a...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Islets of Langerhans. (a) Medium-power photomicrograph of an islet of Langerhans (I) embedded in the exocrine component (E) of the pancreas. The islets, roughly
spherical, are composed of much smaller cells than the exocrine pancreas, from which t...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Islets of Langerhans. (a) Medium-power photomicrograph of an islet of Langerhans (I) embedded in the exocrine component (E) of the pancreas. The islets, roughly
spherical, are composed of much smaller cells than the exocrine pancreas, from which t...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Insulin-Secreting Cells. (a) Immunocytochemical method for insulin. (b) Immunocytochemical method for amylin (same islet). Insulin/amylin-secreting cells occupy the
central area of the pancreatic islets and are the most common cell type. These cel...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Glucagon-Secreting Cells. Glucagon-secreting cells are located mainly at the periphery of the pancreatic islets, as shown in this micrograph of a section stained to show
glucagon by an immunoperoxidase technique. Glucagon-secreting cells possess s...

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Endocrine System
Lowe, James S., BMedSci, BMBS, DM, FRCPath, Stevens & Lowe's Human Histology, 14, 246-266

Somatostatin-Secreting Cells. Somatostatin-secreting cells are a minority population and, in humans, are scattered apparently randomly throughout the pancreatic islets,
as shown in this micrograph stained to show somatostatin by an immunoperoxidas...

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Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

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Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

Endocrine System
Ovalle, William K., PhD, Netter's Essential Histology, 10, 231-261

(no summary available)

Copyright © 2021 Copyright © 2021 by Elsevier, Inc. All rights reserved.

ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Histology of the thyroid gland

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Structure of the thyroid follicular cells

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Synthesis and secretion of thyroid hormones T 3 and T 4

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Graves' disease

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Graves' disease

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Structure and function of the parathyroid gland

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Synthesis and mechanism of action of calcitonin Immunohistochemistry panel from Martín-Lacave I, García-Caballero T: Atlas of Immunohistochemistry. Madrid, Spain:Ed.
Díaz de Santos, 2012.

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Steroid-producing cells of the adrenal cortex (zona reticularis)

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Histology organization of the adrenal gland

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Steroid-producing cells of the adrenal cortex (zona fasciculata)

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Synthesis of steroids in the adrenal cortex

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Adrenal medulla: Synthesis of catecholamines

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Blood supply to the adrenal gland

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Islets of Langerhans Immunohistochemistry panels from Martín-Lacave I, García-Caballero T: Atlas of Immunohistochemistry. Madrid, Spain:Ed. Díaz de Santos, 2012.

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Fine structure and synthesis and secretion of insulin by B cells

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Uptake and fate of glucose in an adipose cell

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Clinical forms of diabetes mellitus

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

Clinical aspects of T1DM and T2DM

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ENDOCRINE SYSTEM
Kierszenbaum, Abraham L., M.D., Ph.D., Histology and Cell Biology: An Introduction to Pathology, 19, 631-662

(no summary available)

Copyright © 2020 Copyright © 2020 by Elsevier, Inc. All rights reserved