Active Transport

E book page 205-206

Warm Up
Essential questions
• What is required for molecules to move from low concentration to
high concentration?
• What molecules can easily pass across a
membrane?(charged/neutral)
• Why active transport needed ATP?
Vocabulary
• Uniport
• Symport 
• Antiport 
• Na+/K+-ATPase pump
Lesson Objectives
• Define Active transport
• Differentiate between uniport, symport and antiport.
• Deduce the steps involved in the working of Na+/K+-ATPase pump
LO1:Define Active transport(Individual work)

• Observe the picture carefully and

write the definition of active
transport in your notebook.
Let's define....
• “Active Transport is defined as a process that involves the
movement of molecules against the concentration gradient with
the use of ATP.”
AFL
LO2:Differentiate between uniport, symport and antiport.(Group Discussion)

• Watch the video and answer the following questions

• https://www.youtube.com/watch?v=AFXUl0MnLlk
1. Define uniport, symport and antiport
2. Give examples of each transport.
LET'S DEFINE
• I) Uniport: When a single substance moves in a single
direction across a cell membrane, it is called uniport.
•
II) Antiport: When two substances move in the opposite
direction across a cell membrane, it is called antiport.
•
III) Symport: When two substances move in the same
direction across a cell membrane, it is called symport.
Let's draw.....
•
LO3:Deduce the steps involved in the working of Na+/K+-
ATPase pump(Individual work)
• Watch the video and write the steps involved in the working of
sodium potassium pump.
• https://www.youtube.com/watch?v=_bPFKDdWlCg
• 3 sodium ions bind to intracellular sites on the sodium-potassium pump
• A phosphate group is transferred to the pump via ATP hydrolysis
• The pump undergoes a conformational change, translocating sodium
across the membrane
• The conformational change exposes two potassium binding sites on the
extracellular surface of the pump
• The phosphate group is released which causes the pump to return to its
original conformation
• This translocates the potassium across the membrane, completing the ion
exchange
AFL
1. Define active transport?
2. Differentiate between antiport and symport?
3. Applying the knowledge of different types of transport, Sodium
potassium pump is an example of uniport, symport or antiport?
Let's think critically
• Why do ions have a difficult time getting through plasma membranes
despite their small size?
Wrap Up
• Find answers to the essential questions.