This document discusses human reproductive anatomy and physiology. It describes the development of reproductive organs from conception through puberty for both males and females. Key details include the roles of hormones like estrogen, progesterone, FSH and LH in sexual maturation and function. The structures and functions of the male and female reproductive systems are outlined, including the testes/ovaries, genitals and role in reproduction. Pubertal changes for both sexes are also summarized.
This document discusses human reproductive anatomy and physiology. It describes the development of reproductive organs from conception through puberty for both males and females. Key details include the roles of hormones like estrogen, progesterone, FSH and LH in sexual maturation and function. The structures and functions of the male and female reproductive systems are outlined, including the testes/ovaries, genitals and role in reproduction. Pubertal changes for both sexes are also summarized.
This document discusses human reproductive anatomy and physiology. It describes the development of reproductive organs from conception through puberty for both males and females. Key details include the roles of hormones like estrogen, progesterone, FSH and LH in sexual maturation and function. The structures and functions of the male and female reproductive systems are outlined, including the testes/ovaries, genitals and role in reproduction. Pubertal changes for both sexes are also summarized.
Reproductive Development Begins during intrauterine life Full function is initiated at puberty Hypothalamus – synthesis and releases GnRH Anterior pituitary gland – release FSH and LH FSH and LH – initiate production of androgen and estrogen Initiate visible signs of maturity – secondary sex characteristic Intrauterine Development Sex – determined at the moment of conception Gonad – body organ that produces sex cells (testis-males, ovary-females) Week 5 – primitive gonadal tissue is already formed Week 7 or 8 – differentiates into primitive testes Testosterone formation begins Mesonephric (wolffian) – develop into the male reproductive organ Week 10 – testosterone not present Gonadal tissue differentiates into ovaries Paramesonephric (mullerian) – develops into female reproductive organs Oocytes – cells that develop into eggs throughout woman’s mature years Already formed in ovaries Week 12 – external genitals become visible Testosterone secretion halted in utero – chromosomal male born with female- appearing genitalia Testosterone during pregnancy – chromosomal female born with male- appearing genitalia Pubertal Development Secondary sex characteristics begin Girls – develop earlier Role of Androgen Androgenic hormones Responsible for muscular development, physical growth, and increase in sebaceous gland secretions Males - adrenal cortex and testes Females – adrenal cortex and ovaries Testosterone in males: Development of: Testes, scrotum, penis, prostate and seminal vesicles Axillary and facial hair Laryngeal enlargement accompanied by voice change Maturation of spermatozoa Closure of growth in long bones Testosterone in females: Enlargement of the labia majora and clitoris Formation of axillary and pubic hair Adrenarche Role of Estrogen Triggered by FSH Excreted by ovarian follicle Estrone (E1), estradiol (E2), estriol (E3) Influences the development of: Uterus, fallopian tubes, vagina Typical female fat distribution and hair patterns Breast - trelarche End to growth Secondary Sex Characteristics Girls Order of changes: 1. Growth spurt 2. Increase in the transverse diameter of the pelvis 3. Breast development 4. Growth of pubic hair 5. Onset of menstruation 6. Growth of axillary hair 7. Vaginal secretions Menarche – the first menstrual period Ave. age – 12.5 years 9 – 17 years old First year – irregular Males Production of spermatozoa does not begin in intrauterine life Produced in a continuous process From puberty throughout life span 64 days - mature Order of change: 1. Increase in weight 2. Growth of testes 3. Growth of face, axillary, pubic hair 4. Voice changes 5. Penile growth 6. Increase in height 7. Spermatogenesis Anatomy and Physiology
The Reproductive System
Gynecology – study of the female reproductive organs Andrology – study of the male reproductive organs Male Reproductive System External structures: 1. Scrotum Support the testes and help regulate the temperature of the skin 2. Testes Leydig’s Cells – responsible for production of the male hormone testosterone Seminiferous tubules – produce spermatozoa FSH – resposible for the release of androgen- binding protein (ABP) LH – responsible for the release of testosterone One testis is slightly larger than the other 3. Penis 2 Corpus cavernosa Corpus spongiosum Penile artery – provides blood supply for the penis Parasympathetic nerve – penile erection Glans – bulging, sensitive ridge of tissue Prepuce – retractable skin protecting the glans Circumsicion – removal of the prepuce Internal structures: 1. Epididymis – approx 20 foot long Conducts sperm from the testis to the vase deferens 2. Vas deferens (ductus deferens) Carries sperm from the epididymis to seminal vesicles and the ejaculatory ducts Spermatic cord – blood vessels and the vas deferens 3. Seminal vesicle Empty into the urethra by way of the ejaculatory ducts Produces a viscous portion of the semen 4. Ejaculatory ducts Pass through the prostate gland and join the seminal vesicles to the urethra 5. Prostate gland Chestnut-sized gland that lies below the bladder Secretes thin, alkaline fluid 6. Bulbourethral glands Cowper’s gland Secrete alkaline fluid Semen – prostate gland (60%), seminal vesicles (30%), epididymis (5%), bulbourethral glands (5%) 7. Urethra Approx 8 in (18 to 20cm) Female Reproductive System External Structures: 1. Mons veneris – protect the junction of the pubic bone from trauma 2. Labia minora – abundant with sebaceous glands 3. Labia majora – protection for the external genitalia and thedistal urethra and vagina 4. Vestibule – flattened surface inside the labia Give rise to the urethra and the vagina 5. Clitoris – 1 to 2 cm rounded organ of erectile tissue Center of sexual arousal and orgasm 6. Prepuce – covers the clitoris 7. Skene’s gland (paraurethral glands) – one on each side of the urethral meatus 8. Bartholin’s gland (vulvovaginal glands) – located lateral to the distal vagina Both glands – secretions help lubricate the external vagina Secretions with alkaline pH 9. Fourchette – ridge tissue formed by the posterior joining of the two labia minora and labia majora Cut during childbirth 10. Perineal body – muscular area 11. Hymen – semicircle of tissue that covers the opening of the vagina Blood Supply Pudendal artery and inferior rectus artery – supply the external genitalia Pudendal vein – venous return Nerve Supply Ilioinguinal and genitofemoral nerves (L1) – anterior portion of the vulva Pudendal nerve (S3) – posterior portions of the vulva and vagina Internal Structures: 1. Ovaries – produce, mature and discharge ova Produce estrogen and progesterone Estrogen – prevent osteoporosis Keep cholesterol levels reduced Principal divisions: A. Protective layer of epithelium B. Cortex – filled with ovarian and graafian follicles C. Central medulla – contains nerves, blood vessels, lymphatic tissue and some smooth muscle tissue 2. Fallopian tubes – approx 10cm long Convey the ovum from the ovaries to the uterus Provide a place for fertilization Interstitial – lies within the uterine wall 1cm long 1mm in diameter Isthmus – 2cm long Portion that is cut and sealed in a tubal ligation Ampulla – 5cm long Fertilization takes place Infundibulum – 2 cm long Funnel-shaped Rim is covered with fimbriae Lining is composed of mucous membrane and ciliated cells Produces peristaltic movement 3. Uterus – hollow, muscular, pear-shaped organ 8 years of age – increase in the size of the uterus begins 17 years of age – reaches adult size Functions: Receive the ovum from the fallopian tube Provide a place for implantation Nourishment during fetal growth Furnish protection to a growing fetus Expel fetus from woman’s body Divisions: Body or corpus – uppermost part Expands to contain the growing fetus Cornua – upper aspects Fundus – portion of the uterus between the points of attachment of the fallopian tubes Isthmus – short segment between the body and cervix Enlarges to accommodate the aid in accommodating the growing fetus Most commonly cut in CS Cervix – lowest portion Cervical canal – central cavity Internal cervical os – opening of the canal at the junction of the cervix and isthmus External cervical os – distal opening to the vagina Uterine Layers Endometrium – innermost, mucous membrane Basal layer – closest to the uterine wall Not influenced by hormones Glandular layer – influenced by estrogen and progesterone Grows and becomes thick Shed as menstrual flow Myometrium – middle one, muscle fibers Constrict the tubal junctions Holds the internal cervical os Constrict blood vessels Myomas, benign uterine tumors Perimetrium – outer one, connective tissue Add strength and support to the structure Cervical Layer Endocervix – mucous membrane Secrete mucus Estrogen peak – 700ml/day Estrogen very low – few milliliters Stratified squamous epithelium – similar to the lining of the vagina Important when obtaining a Papanicolaou smear Uterine Blood Supply Uterine arteries – uterus Ovarian artery – ovary Joins the uterine artery Uterine veins – empty into the internal iliac veins Uterine Nerve Supply Supplied by efferent (motor) and afferent (sensory) nerves Efferent – T5 to T10 Afferent – T11 to T12 Epidural anesthesia Uterine Supports Posterior ligament – forms Douglas’ cul-de- sac Broad ligaments – cover the uterus front and back and extend to the pelvic sides Round ligaments – steady the uterus 4. Vagina – organ of intercourse Convey sperm to the cervix Birth canal Anterior wall – 6-7 cm Posterior wall – 8-9 cm Fornices – recesses on all sides of the cervix Anterior fornix – front Posterior fornix – behind Pooling of semen Lateral fornix – sides Rugae – folds Bulbocavernosus – circular muscle at the external opening of the vagina Blood Supply - Vaginal artery Nerve – sympathetic and parasympathetic at S1 to S3 levels Glycogen rich – broken down by Doderlein’s bacillus Breast Ectodermic tissue Estrogen – increase in size Connective tissue and deposition of fat Glandular tissue – undeveloped Milk glands – 20 lobes Acinar cells – produce milk Lactiferous duct – reservoir for milk Nipple – transmits sensations to the posterior pituitary gland to release oxytocin Oxytocin – constricts milk gland cells and push milk forward Areola – Montgomery’s tubercles Blood supply – axillary, internal mammary and intercostal arteries Pelvis Support and protect Four united bones: 1. 2 Innominate bones 2. Coccyx 3. Sacrum Innominate bones: 1. Ilium – iliac crest 2. Ischium Ischial tuberosities Ischial spines 3. Pubis – symphysis pubis Sacrum – sacral prominence Coccyx – 5 fused small bones Divisions False pelvis: Superior half Supports the uterus Aids in directing the fetus into the true pelvis True pelvis: Inferior half Linea terminalis: Imaginary line that divides the true and false pelvis Drawn from the sacral prominence to the superior aspect of the symphysis pubis Inlet - entrance to the true pelvis Outlet – inferior portion of the pelvis Pelvic cavity – space between the inlet and outlet Curved Slows and controls the speed of birth Compresses the chest of the fetus Midplane – level of the ischial spines