Lecture one- Pharmacy collage

first Year
Analytical Chemistry
Such as the amount of Active compounds in pharmaceutical
formulations or biological samples.
There are also different methods such as separation methods for
example chromatographic separation methods.
Molar mass(M) or Molecular weight(M.Wt)
 Molarity(M)= (mass / M.Wt) x (1000/Volume(ml))…. For solids
Molarity(M)= (Sp.grafity x w/w% x 1000) / M.Wt(g/mole).. For liquids
1dL(diciliter) = 100mL
= (V)
Equivalent= is the mass of material providing Avogadro's number of
reacting units.
Formality (F)
is the No of formula weight of a solute dissolved in 1 L solution.
F= number of formula weight /L
or F= mili formula weight/ml
Example :
Exactly 5.00 g NaCl are dissolved in 100ml distilled water .calculate
the formality of this solution?
No of formula weight= weight(gm) / gram F.Wt
F.wt=5.00/58.44= 0.0856

Formality = 0.0856 /(100×0.001) = 0.856 gf.wt /L

Formality(F) is numerically the same as Molarity(M) . F is used for
ionic salts that do not exist as molecules in the solid or in the
solution.
Formality = Molarity numerically
F is used for total analytical concentration .
M is used for equilibrium concentration.
Molality(m) = mole of solute/1000g solvent
The calculations of this type involved:
1- Convert the mass of compound to equivalent moles.
2- multiply by stoichiometric factor.
3- reconversion the data in mole to the metric units.
Thanks