the first animal followed by sheep, goats, cattle and others.
The selection of animals into different forms has
been practiced over a long period of time.
Many thousands years ago, people were using
applied genetics in the form of plant and animal breeding. Evolution: Gradual changes which species undergo over time as a result of natural selection Charles Darwin: origin of species Time Line: Wild to Domestication (Evolution) = Types Breeds Composites Transgenic & MAS Breed: a group of animals of common origin that possess certain distinguishable characteristics that make them different than other members of the species. Animal Breeding: encompasses Molecular, quantitative, and population genetics The application of the principles of genetics
and statistics for improving performance of
farm animals The practical application of genetic analysis
for development of lines/breeds of
domestic animals suited to human purposes/uses. The 18th century English farmer Robert Bakewell is regarded as the father of modern animal breeding in laying foundations of pure animal breeds of (Shire horse, Longhorn cattle and Leicester sheep breed). Robert Bakewell (1725 – 1795) did his animal breeding work in 1760 at Dishley, Leicestershire, England on horse, cattle and sheep. He succeeded to develop pure breeds because of: Then, Bakewell aimed to choice early maturity, shorter legs, a minimum bone, wide hips, a barrel shaped body, a thinner hide and plenty of fat. Many others followed Bakewell’s method to develop pure breeds in many countries. Formation of pure breed associations took place during 1870 – 1900 and registry books for each breed were developed. William Bateson working on chickens showed the applicability of Mendelian principles on animals. Hardy and Weinberg contributed population genetics. Other scientists also have advanced our understanding of qualitative and statistical nature of animal breeding. (E.g. biometricians like Karl Pearson, Ronald Fisher etc.) Wright Sewall gave the details of different type of mating systems during 1918 – 1921. Lush, Jay American scientist gave the details of heritability estimation and its effect on selection of animals in 1945. He developed a breeder’s equation; i.e R= h2S. Lush applied Mendel's work directly to animal breeding. In 1997, Ian Wilmut Created the first true clone, the Dorset
ewe, Dolly Dolly, 1st animal to be cloned from an adult
somatic cell, using the process of nuclear
transfer at Roslin Institute, Scotland 1. It is applied science that is important to increase the progeny of best animal w/c fits requirement of both producer and consumer 2. It is tool for genetic improvement in performance of the livestock over generations Increase yield by selecting the best parents: to improve the productivity of progeny interms of milk, egg, wool, meat, etc. Identify and avoid animals with bad genes/genetic defects Produce disease tolerant animal: such as disease-resistant
strains of chickens and heat resistant breeds of cattle using
d/t breeding technologies The objective of animal improvement/breeding should be to increase the efficiency of production. In economic terms, the output to be obtained from the improvement should exceed the cost of input. The outputs could be production of milk, meat, egg, wool, etc The inputs include feed, land, capital, labor, veterinary services, etc. it may not be easy to estimate the cost of inputs accurately but it is important to recognize that they exist. There are many ways of changing the productivity of livestock. These include: Improved feeding
Management (including the physical environment)
Health care
Animal breeding (genetic improvement)-selection
and crossbreeding etc….
Genetic improvement is always accompanied with management (environment) because almost 70% of the genetic improvement is possible through only management improvement. So, we need to consider the resource we have before going for genetic improvement. The cost of improvement through better environment is very high and continuous throughout the entire improvement program. Genetic improvement can be made through: Substituting one breed for another ( breed replacement) Selection Mating systems Cross breeding Inbreeding Genetic Engineering Marker assisted selection, MAS Genome selection, DNA based Uses of Biotechnology for multiplying the best genotype (AI, ETT, Cloning etc.) A trait is any observable or measurable characteristic of an animal. Qualitative traits Quantitative traits Phenotypic expressions of traits are phenotypic expressions of traits are measurable observable (metric) show variation which fall into a few show all mode of variation ranges from small to clearly defined classes (suggest large (suggest continuous variation) discontinuous variation) are determined by a large number of genes(QTL) are under the control of one or a few which have relatively small individual effects, pairs of genes, whose final expression additive effect(GA) is not greatly influenced by are affected in their expression to a environment considerable extent by environment examples: includes most of the economic traits in domestic - presence or absence of horn in cattle, animals - black or red coat color, examples: - blood types etc. - Milk production, - egg yield, - egg size, - wool yield, - growth rate, etc. Nature of Variation Variation - is the measurable differences in individuals for a particular character. - is the raw material which the breeder has available for herd/flock
improvement - is at once the hope and despair of the breeder:
Nature of variation could be continuous or discontinuous.
What is their difference?
Why traits have continuous phenotypes
= The genetic factors are due to
Recombination effect during gamete formation and fertilizations
Gametes combine at random during fertilization
random sample of Genes combine at random during meiosis
Numerous genes affect the expression of a trait (polygenic effect)
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