Name of Drug Brand Name: TRANEXAMIC ACID Generic Name: Cyklokapron, Lysteda

Actions > inhibits activation of plasminogen

Indications > used for the treatment of severe localized bleeding secondary to hyperfibrinolysis, including epistaxis, hyphema, or hypermenorrhea (menorrhagia) and hemorrhage following certain surgical procedures, such as conization of the cervix > used for the management of hemophilic patients >used for the treatment of hereditary angioedema

Contraindications > acquired defective color vision,

since this prohibits measuring one endpoint that should be followed as a measure of toxicity. > Subarachnoid hemorrhage. Anecdotal experience indicates that cerebral edema and cerebral infarction may be caused by CYKLOKAPRON in such patients. > Active intravascular clotting.

Nursing Responsibilities >assess baseline BP and pulse before starting IV. >anticipate reduced dosage in patients with impaired renal function. >observe patient with signs and symptoms of thrombosis

Name of Drug Brand Name: FLUIMUCIL Generic Name: ACETYLCYSTEINE

Actions > exerts an intense mucolytic action on mucous and mucopurulent secretions, by depolymerizing the mucoproteic complexes and the nucleic acids which confer viscosity to the vitreous and purulent component of the sputum and of other secretions.

Indications > used for treatment of respiratory affections characterized by thick and viscous hypersecretions, chronic bronchitis and exacerbation; pulmonary emphysema, mucoviscidosis and bronchiectasis.

Contraindications >MAO inhibitor therapy within 14days initiating therapy. >severe hypertension >Coronary artery disease, hypersensitivity due to pseudoedephrine, acrivastine or any component. >renal impairment

Nursing Responsibilities >monitor effectiveness of therapy and advent of adverse effects. >instruct patient in appropriate use and adverse effects to report. >assess the patients vital signs >bronchial tapping >monitor for bronchospasm

Name of Drug Brand Name: SINECOD FORTE Generic Name: BUTAMIRATE CITRATE

Actions acts centrally on brain (vagus nerve) or locally on the respiratory tract to suppress the cough reflex.

Indications used for acute cough of any etiology. used for pre and post op cough sodation for surgical procedures and brochoscopy.

Contraindications
Hypersensitivity to drug

Nursing Responsibilities > Assess cough type and frequency. >Monitor the adverse reactions. >Assess patients vital signs. >Assess sleep patterns. >Instruct patient to cough effectively, sit upright and take several deep breaths before attempting. >Advice patient to minimize cough to prevent irritants. >Caution patient to avoid any activities requiring alertness until response to medication is known.

Name of Drug Brand Name: DUAVENT Generic Name: IPRATROPIUM SALBUTAMOL

Actions >treatment of obstructive airway diseases >bronchodilator

Indications >management of reversible bronchospasm associated obstructive airway disease. >patient with COPD on a regular inhaled bronchospasm and who required a bronchodilator

Contraindications
>hypertrophic obstructive cardiomyopathy or tachyarrythmia >hypersensitivity to atropine and its derivatives

Nursing Responsibilities >drugs should be given only if the potential benefit justifies the potential risk to the fetus. >position patient on high back rest position >do back tapping after you nebulizer the patient >do not give a food immediately, it can cause vomiting

Name of Drug Brand Name: CEFTIN Generic Name: CEFUROXIME

Actions > inhibits synthesis of bacterial cell wall, causing cell death.

Indications >it is effective for the treatment of penicillinase. >effectively treats bone and joint infections, bronchitis, meningitis, gonorrhea, otitis media, pharyngitis, lower respiratory tract infections, skin and soft tissue infections, urinary tract infections and is used for surgical prophylaxis or eliminating infections.

Contraindications >hypersensitivity to cephalosporins and related antibiotics, pregnancy lactation. >can cause diarrhea, nausea, vomiting, headache, migraine and abdominal pain if tolerated.

Nursing Responsibilities >determine history of hypersensitivity reactions to cephalosporins, penicillins and history of allergies, particularly to drugs before therapy is initiated. >inspect IM and IV injection sites frequently for signs of phlebitis. >report onset of loose stools or diarrhea. >monitor I&O rates and pattern; especially important in severely ill patients receiving high doses. Report any significant changes.

Name of Drug Brand Name: ANSIMAR TAB Generic Name: DOXOFYLLIN

Actions >bronchodilator

Indications >treatment of bronchial asthma and pulmonary disease with spastic bronchial component.

Contraindications >individuals who have shown to hypersensitivity to Ansimar and its components. >patient with acute myocardial infarction and hypotension. >in nursing mothers.

Nursing Responsibilities >may be taken with or without food. >store at room temperature not exceeding 30C

Name of Drug Brand Name: DIAMICRON Generic Name: GLICLAZIDE

Actions >works mainly by stimulating the cells in the pancreas that produces insulin. >causes the beta cells to produce more insulin.

Indications >control of hyperglycemia in gliclazide responsive diabetes mellitus of stable

Contraindications >used with caution in elder people, decreased kidney function and decreased liver function.

Nursing Responsibilities >take exactly as directed; with meals at the same time each day. >do not change dose or discontinue without consulting the prescriber. >avoid alcohol while taking this medication. >do not introduce new medication without consulting the prescriber. >maintain regular dietary intake and exercise routine and always carry quick source of sugar with you.

Name of Drug Brand Name: KALIUM DURULE Generic Name: POTASSIUM CHLORIDE

Actions > Supplemental potassium in the form of high potassium food or potassium chloride may be able to restore normal potassium levels.

Indications > used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. >Prophylaxis during treatment w/ diuretics.

Contraindications >Renal insufficiency, hyperkalemia, untreated Addison's disease, constriction of the esophagus &/or obstructive changes in the alimentary tract. >allergy to tartrazine, aspirin (tartrazine is found in some preparations marketed as Kaon-Cl, Klor-Con); severe renal impairment with oliguria, anuria, azotemia; hyper adynamia episodica hereditaria; acute dehydration; heat cramps; GI disorders that delay passage in the GI tract. Use cautiously with cardiac disorders, especially if treated with digitalis

Nursing Responsibilities > take each dose with meals mixed in water or other suitable liquid. > take this medicine following the frequency and amount prescribed by the physician. This is especially important if the patient is also taking diuretics and/or digitalis preparations. > inform patients that this product contains as a dispersing agent the stool softener, docusate sodium, this may change stool consistency, or, rarely, produce diarrhea or cramps. > check with the physician at once if tarry stools or other evidence of gastrointestinal

bleeding is noticed.

Name of Drug Brand Name: AMOXCIL Generic Name: COAMOXICLAV

Actions >is an antibiotic that is a combination of a penicillin (amoxicillin) and a substance called clavulanic acid. It kills bacteria, by interfering with their ability to form cell walls. The bacteria therefore break up and die.

Indications >Abdominal infections >Animal bites >infections of the organs associated with breathing, including nasal passages, sinuses, trachea and lungs. >infections of the sex organs and other organs associated with urination. >inflammation of the connective tissue, commonly the skin

Contraindications >history of allergies, severe hepatic impairment, geriatric patient, aoric stenosis, pregnancy, lactation and liver disease.

Nursing Responsibilities >assess for infection >obtain specimens for culture and sensitivity prior to therapy. >monitor bowel function >advice the patient to report the signs of any super infection. >instruct the patient to take the medication around the clock and to finish the drug completely as directed. >Review use and preparation of tablets for oral suspension. >Review use and preparation of tablets for oral suspension

Name of Drug

Actions

Indications

Contraindications

Nursing Responsibilities

Brand Name: MEPTIN Generic Name: PROCATEROL HCI

>bronchodilator >prompt onset and long duration of action, high selectivity for the 2-adrenergic receptors of the bronchial smooth muscle, marked antiallergic action, insignificant hemodynamic effect.

>Treatment of dyspnea and other symptoms due to the following airway obstructions: Bronchial asthma, chronic bronchitis and pulmonary emphysema.

>history of hypersensitivity to any of the ingredients of this drug.

>

Name of Drug Brand Name: FIXCOM Generic Name: Rifampicin , Isoniazid , Pyrazinamide, Ethambutol

Actions >Rifampicin: is readily

absorbed from the GIT and peak plasma concentrations of about 710 mcg/mL have been reported 2-4 hrs after a dose of 600 mg, although there may be considerable interindividual variation. Food may reduce and delay absorption. Rifampicin is approximately 80% bound to plasma proteins. It is widely distributed in body tissues and fluids and diffusion into the CSF is increased when the meninges are inflamed. >Isoniazid: is readily absorbed from the GIT. Peak concentrations of about 3-8 mcg/mL appear in blood 1-2 hrs after a fasting dose of 300 mg by mouth. The rate and extent of absorption of isoniazid is reduced by food. Isoniazid is not considered to be bound appreciably to plasma proteins and diffuses into all body tissues and fluids, including the CSF. The plasma half-life for isoniazid ranges from about 1-6 hrs, those who are fast acetylators having shorter half-lives. >Pyrazinamide: is readily absorbed from the GIT. Peak serum concentrations occur about 2 hrs after a dose by mouth and have

Indications >Treatment of pulmonary & extrapulmonary TB.

Contraindications >Rifampicin: Patients w/ jaundice. >Pyrazinamide: Liver damage, acute gout or hyperuricemia. >Ethambutol: Optic neuritis.

Nursing Responsibilities >careful monitoring of hepatic function. >check hepatic function before and during treatment. >monitor liver function and serum uric acid regularly. >caution when assessing visual acuity in patients with cataracts to make sure that changes are not due to the underlying causes .

been reported to be about 35 mcg/mL after 1.5 g and 66 mcg/mL after 3 g. Pyrazinamide is widely distributed in the body fluids and tissues and diffuses into the CSF. The half-life has been reported to be about 9-10 hrs. It is metabolized primarily in the liver by hydrolysis to the major active metabolite pyrazinoic acid which is subsequently hydroxylated to the major excretory product 5hydroxypyrazinoic acid. >Ethambutol: s distributed to most tissues, including the lungs, kidneys and erythrocytes. It diffuses into the CSF when the meninges are inflamed. It has been reported to cross the placenta and is distributed into breast milk. The elimination halflife following oral administration is about 3-4 hrs.

Name of Drug Brand Name: MORIAMIN FORTE Generic Name: CALCIUM PANTOTHENIC

Actions > Restoration and maintenance of body resistance.

Indications >malnutrition, protein and vitamin deficiencies, anemia, concalascence,

Contraindications >patients with malabsorption syndrome

Nursing Responsibilities >assess patient for signs of vitamin deficiency before and periodically throughout therapy. >assess nutritional status through 24hour diet recall. >determine frequency of consumption of vitamin rich foods.