Medical MicroAnatomy Cadaver Histologic Features Report Gross Anatomy Table #: 11 Slide Label: 3 Expected Features: Name: Specimen:

: Liver-left lobe-inferior portion

The liver, when viewed in an H&E stain, appears eosinophilic with dark stained nuclei. In an adult the hepatocytes are arranged in single cell columns with blood sinusoids coursing between the rows of cells. The sinusoids lead to and drain at a central vein. On the parameter of the central veins are portal triads which contain a hepatic artery, portal vein, and a bile duct. The hepatic artery generally appears to be the smallest with a layer of endothelium on the lumen side surrounded by a layer of smooth muscle. The portal vein appears to have the largest lumen and lacks a muscle layer. The bile duct is around the same size as the artery and the lumen is lined with simple cuboidal epithelium.

Observed Features:

The tissue in this sample appeared eosinophilic, as was expected. The sinusoidal spaces did seem to be wider than what is seen in normal livers, which could be a sign of congestion. Interspersed throughout the sinusoidal spaces were basophilic cells which may have been granular. The central veins appeared to be full of unidentifiable material, but the tissue in the sample didnt appear to have undergone necrosis. There were identifiable portal triads and the components of those contained nothing remarkable. The hepatocytes were all arranged in single column fashion between sinusoids, which is normal in adults. The nuclei of the hepatocytes appeared round and pink and slightly hypertrophied from what was expected, but again they did not appear necrosed.

Conclusion (Normal/Abnormal): This sample of liver appears to be normal.